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Genetic Network Inference: From Co-Expression Clustering To Reverse Engineering

by Patrik D'Haeseleer, Shoudan Liang, Roland Somogyi , 2000
"... motivation: Advances in molecular biological, analytical and computational technologies are enabling us to systematically investigate the complex molecular processes underlying biological systems. In particular, using highthroughput gene expression assays, we are able to measure the output of the ge ..."
Abstract - Cited by 336 (0 self) - Add to MetaCart
motivation: Advances in molecular biological, analytical and computational technologies are enabling us to systematically investigate the complex molecular processes underlying biological systems. In particular, using highthroughput gene expression assays, we are able to measure the output

Hierarchical Bayesian Inference in the Visual Cortex

by Tai Sing Lee, David Mumford , 2002
"... this paper, we propose a Bayesian theory of hierarchical cortical computation based both on (a) the mathematical and computational ideas of computer vision and pattern the- ory and on (b) recent neurophysiological experimental evidence. We ,2 have proposed that Grenander's pattern theory 3 coul ..."
Abstract - Cited by 300 (2 self) - Add to MetaCart
of Zhu and colleagues 7, 8 might be the most successful recent application of this proposal in solving real and difficult computer vision problems using generafive models, though its connection to the visual cortex has not been explored. Here, we bring in a powerful and widely applicable paradigm from

Physical symbol systems

by Allen Newell - Cogn. Sci
"... to review the basis of common understanding between the various disciplines. In my estimate, the most fundamental contribution so far of artificial intelligence and computer science to the joint enterprise of cognitive science has been the notion of a physical symbol system, i.e., the concept of D b ..."
Abstract - Cited by 270 (3 self) - Add to MetaCart
to review the basis of common understanding between the various disciplines. In my estimate, the most fundamental contribution so far of artificial intelligence and computer science to the joint enterprise of cognitive science has been the notion of a physical symbol system, i.e., the concept of D

Application of hierarchical linear models to assessing change.

by Anthony S Bryk , Stephen W Raudenbush - Psychological Bulletin, , 1987
"... Recent advances in the statistical theory of hierarchical linear models should enable important breakthroughs in the measurement of psychological change and the study of correlates of change. A two-stage model of change is proposed here. At the first, or within-subject stage, an individual's s ..."
Abstract - Cited by 207 (5 self) - Add to MetaCart
, and possibly experimental treatments. This two-stage conceptualization, illustrated with data on Head Start children, allows investigators to model individual change, predict future development, assess the quality of measurement instruments for distinguishing among growth trajectories, and to study systematic

A Meta-Study of Algorithm Visualization Effectiveness

by Christopher D. Hundhausen, Sarah A. Douglas, John T. Stasko
"... Algorithm visualization (AV) technology graphically illustrates how algorithms work. Despite the intuitive appeal of the technology, it has failed to catch on in mainstream computer science education. Some have attributed this failure to the mixed results of experimental studies designed to substant ..."
Abstract - Cited by 166 (2 self) - Add to MetaCart
of AV technology, we present a systematic metastudy of 24 experimental studies. We pursue two separate analyses: an analysis of independent variables, in which we tie each study to a particular guiding learning theory in an attempt to determine which guiding theory has had the most predictive success

The Use of Computational Intelligence in Intrusion Detection Systems: A Review

by Shelly Xiaonan Wu, Wolfgang Banzhaf , 2008
"... Intrusion detection based upon computational intelligence is currently attracting considerable interest from the research community. Characteristics of computational intelligence (CI) systems, such as adaptation, fault tolerance, high computational speed and error resilience in the face of noisy inf ..."
Abstract - Cited by 46 (0 self) - Add to MetaCart
, evolutionary computation, artificial immune systems, swarm intelligence, and soft computing. The research contributions in each field are systematically summarized and compared, allowing us to clearly define existing research challenges, and to highlight promising new research directions. The findings

Modeling Botnet Propagation Using Time Zones

by David Dagon, Cliff Zou, Wenke Lee - In Proceedings of the 13 th Network and Distributed System Security Symposium NDSS , 2006
"... Time zones play an important and unexplored role in malware epidemics. To understand how time and location affect malware spread dynamics, we studied botnets, or large coordinated collections of victim machines (zombies) controlled by attackers. Over a six month period we observed dozens of botnets ..."
Abstract - Cited by 132 (10 self) - Add to MetaCart
representing millions of victims. We noted diurnal properties in botnet activity, which we suspect occurs because victims turn their computers off at night. Through binary analysis, we also confirmed that some botnets demonstrated a bias in infecting regional populations. Clearly, computers that are offline

Prediction Tools for Unfavourable Outcomes in Clostridium difficile Infection: A Systematic Review

by Claire Nour, Abou Chakra, Jacques Pepin, Louis Valiquette
"... Context: Identifying patients at risk for adverse outcomes of Clostridium difficile infection (CDI), including recurrence and death, will become increasingly important as novel therapies emerge, which are more effective than traditional approaches but very expensive. Clinical prediction rules (CPRs) ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
) can improve the accuracy of medical decision-making. Several CPRs have been developed for CDI, but none has gained a widespread acceptance. Methods: We systematically reviewed studies describing the derivation or validation of CPRs for unfavourable outcomes of CDI, in medical databases (Medline

Whom You Know Matters: Venture Capital Networks and Investment Performance,

by Yael Hochberg , Alexander Ljungqvist , Yang Lu , Steve Drucker , Jan Eberly , Eric Green , Yaniv Grinstein , Josh Lerner , Laura Lindsey , Max Maksimovic , Roni Michaely , Maureen O'hara , Ludo Phalippou Mitch Petersen , Jesper Sorensen , Per Strömberg Morten Sorensen , Yael Hochberg , Johnson - Journal of Finance , 2007
"... Abstract Many financial markets are characterized by strong relationships and networks, rather than arm's-length, spot-market transactions. We examine the performance consequences of this organizational choice in the context of relationships established when VCs syndicate portfolio company inv ..."
Abstract - Cited by 138 (8 self) - Add to MetaCart
directly, using for instance the internal rate of return a fund achieved over its ten-year life. However, fund returns in the form required for this study are not systematically available to researchers as VC funds generally do not disclose their performance to anyone other than their own investors

1 A Systematic Review of Predictive Modeling for Bronchiolitis

by Gang Luo (corresponding
"... Purpose: Bronchiolitis is the most common cause of illness leading to hospitalization in young children. At present, many bronchiolitis management decisions are made subjectively, leading to significant practice variation among hospitals and physicians caring for children with bronchiolitis. To stan ..."
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is covered whenever appropriate, as RSV accounts for about 70 % of bronchiolitis cases. Methods: A systematic review was conducted through a PubMed search up to April 25, 2014. The literature on predictive modeling for bronchiolitis was retrieved using a comprehensive search query, which was developed
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