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Genomics update A Proteome Quality Index

by Jan Zaucha, Jonathan Stahlhacke, Matt E. Oates, Natalie Thurlby, Owen J. L. Rackham, Hai Fang, Ben Smithers, Julian Gough
"... pqi-list.org), a much-needed resource for users of bacterial and eukaryotic proteomes. Completely sequenced genomes for which there is an available set of protein sequences (the proteome) are given a one-to five-star rating supported by 11 different metrics of quality. The database indexes over 3000 ..."
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pqi-list.org), a much-needed resource for users of bacterial and eukaryotic proteomes. Completely sequenced genomes for which there is an available set of protein sequences (the proteome) are given a one-to five-star rating supported by 11 different metrics of quality. The database indexes over

The human proteome organization (HUPO) and environmental health

by B. Alex Merrick - EHP Toxicogenomics , 2003
"... analysis of the human proteome. By consolidating national proteome organizations into an international body, HUPO will coordinate international initiatives, biological resources, protocols, standards and data for studying the human proteome. HUPO has identified five key areas to advance study of the ..."
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of the proteome, which become manifest in longterm adverse health effects and disease. Environmental health research stands to greatly benefit from the shared resources, data, and vision of the HUPO organization as a valuable resource in exploiting knowledge of the human proteome toward improving public health

ssOpen AcceResearch An update on the mouse liver proteome

by Biomed Centralproteome Science, Jürgen Borlak, Jürgen Borlak
"... Background: Decoding of the liver proteome is subject of intense research, but hampered by methodological constraints. We recently developed an improved protocol for studying rat liver proteins based on 2-DE-MALDI-TOF-MS peptide mass finger printing. This methodology was now applied to develop a mou ..."
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Background: Decoding of the liver proteome is subject of intense research, but hampered by methodological constraints. We recently developed an improved protocol for studying rat liver proteins based on 2-DE-MALDI-TOF-MS peptide mass finger printing. This methodology was now applied to develop a

A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers

by Limor Gortzak-uzan, Alex Ignatchenko, Andreas I. Evangelou, Mahima Agochiya, Kevin A. Brown, Peter St. Onge, Inga Kireeva, Gerold Schmitt-ulms, Theodore J. Brown, Joan Murphy, Barry Rosen, Patricia Shaw, Igor Jurisica, Thomas Kislinger - J Proteome Res , 2008
"... Epithelial ovarian cancer is the most lethal gynecological malignancy, and disease-specific biomarkers are urgently needed to improve diagnosis, prognosis, and to predict and monitor treatment efficiency. We present an in-depth proteomic analysis of selected biochemical fractions of human ovarian ca ..."
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of the ascites proteome combined with several recently published proteomic data sets of human plasma, urine, 59 ovarian cancer related microarray data sets, and protein–protein interactions from the Interologous Interaction Database I2D

Research Article Proteome analysis of the plasma membrane of Mycobacterium tuberculosis

by Comp Funct Genom, Sudhir Sinha, Shalini Arora, K. Kosalai, Abdelkader Namane, Alexs. Pym, Stewart T. Cole , 2002
"... TheplasmamembraneofMycobacterium tuberculosis is likely to contain proteins that could serve as novel drug targets, diagnostic probes or even components of a vaccine against tuberculosis. With this in mind, we have undertaken proteome analysis of the membrane of M. tuberculosis H37Rv. Isolated membr ..."
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the M. tuberculosis genome database. The two extraction procedures yielded patterns with minimal overlap. Only two proteins, both HSPs, showed a common presence. MALDI–MS analysis of 61 spots led to the identification of 32 proteins, 17 of which were new to the M. tuberculosis proteome database. We

RESEARCH ARTICLE Proteome Exploration to Provide a Resource for the Investigation of Ganoderma lucidum

by Qing Yang, Xiang-dong Ye, Hui Sun
"... Ganoderma lucidum is a basidiomycete white rot fungus that has been used for medicinal purposes worldwide. Although information concerning its genome and transcriptome has recently been reported, relatively little information is available forG. lucidum at the proteo-mic level. In this study, protein ..."
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Ganoderma lucidum is a basidiomycete white rot fungus that has been used for medicinal purposes worldwide. Although information concerning its genome and transcriptome has recently been reported, relatively little information is available forG. lucidum at the proteo-mic level. In this study

Genomic and proteomic databases: Foundations, current status and future applications

by Shamkant B. Navathe, Upen Patil, Wei Guan - Journal of Computing Science and Engineering
"... In this paper we have provided an extensive survey of the databases and other resources related to the current research in bioinformatics and the issues that confront the database researcher in helping the biologists. Initially we give an overview of the concepts and principles that are fundamental ..."
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In this paper we have provided an extensive survey of the databases and other resources related to the current research in bioinformatics and the issues that confront the database researcher in helping the biologists. Initially we give an overview of the concepts and principles that are fundamental

Expansion of the BioCyc collection of pathway/genome databases to 160 genomes

by Peter D. Karp, Christos A. Ouzounis, Caroline Moore-kochlacs, Leon Goldovsky, Pallavi Kaipa, Dag Ahrén, Sophia Tsoka, Nikos Darzentas, Victor Kunin - Nucleic Acids Res , 2005
"... The BioCyc database collection is a set of 160 pathway/genome databases (PGDBs) for most eukaryotic and prokaryotic species whose genomes have been completely sequenced to date. Each PGDB in the BioCyc collection describes the genome and predicted metabolic network of a single organism, inferred fro ..."
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from the MetaCyc database, which is a reference source on metabolic pathways from multiple organisms. In addition, each bacterial PGDB includes predicted operons for the corresponding species. The BioCyc collection provides a unique resource for computational systems biology, namely global

Myelin proteomics: molecular anatomy of an insulating sheath

by Olaf Jahn, Stefan Tenzer, Hauke B. Werner - Mol. Neurobiol , 2009
"... Abstract Fast-transmitting vertebrate axons are electri-cally insulated with multiple layers of nonconductive plasma membrane of glial cell origin, termed myelin. The myelin membrane is dominated by lipids, and its protein composition has historically been viewed to be of very low complexity. In thi ..."
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. In this review, we discuss an updated reference compendium of 342 proteins associat-ed with central nervous system myelin that represents a valuable resource for analyzing myelin biogenesis and white matter homeostasis. Cataloging the myelin pro-teome has been made possible by technical advances

Review Article Calcium Influx and Male Fertility in the Context of the Sperm Proteome: An Update

by Md Saidur Rahman, Woo-sung Kwon, Myung-geol Pang
"... Copyright © 2014 Md Saidur Rahman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Freshly ejaculated spermatozoa are incapable ..."
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that regulate the Ca2+ influx signaling by using the information available from the PubMed database following a MedScan Reader (5.0) search. 1.
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