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, 2006
"... ii iii CHRISTOPHER CHARLES WEIGLE: Displays for Exploration and Comparison of Nested ..."
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ii iii CHRISTOPHER CHARLES WEIGLE: Displays for Exploration and Comparison of Nested
Die Deutsche Bibliothek- Cataloging in Publication Data
, 1996
"... @ Printed on acid-free paper which falls within the guidelines of the ANSI ..."
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@ Printed on acid-free paper which falls within the guidelines of the ANSI
OF
, 2015
"... This Dissertation is brought to you for free and open access by DigitalCommons@URI. It has been accepted for inclusion in Open Access Dissertations ..."
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This Dissertation is brought to you for free and open access by DigitalCommons@URI. It has been accepted for inclusion in Open Access Dissertations
RESEARCH ARTICLE Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by
"... Human immunodeficiency virus (HIV) is a chronic infection that can be managed by antire-troviral treatment (ART). However, periods of suboptimal viral suppression during lifelong ART can select for HIV drug resistant (DR) variants. Transmission of drug resistant virus can lessen or abrogate ART effi ..."
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sensitive point mutation assay for detection of drug resistance mutations in HIV pol. The current OLA involves four main steps from sample to analysis: (1) lysis and/or nucleic acid extraction, (2) amplification of HIV RNA or DNA, (3) ligation of oligonucleotide probes designed to detect single nucleo
Generation and characterization of Rgs4 mutant mice.
- Mol Cell Biol
, 2005
"... RGS proteins are negative regulators of signaling through heterotrimeric G protein-coupled receptors and, as such, are in a position to regulate a plethora of biological phenomena. However, those have just begun to be explored in vivo. Here, we describe a mouse line deficient for Rgs4, a gene norma ..."
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of an 11-kb 5Ј homology arm and a 1.12-kb 3Ј homology arm separated by an Flp recognition target-flanked neo cassette itself preceded by a loxP/spliceacceptor site/promotorless lacZ cassette Production of mice and genotyping. A homologous recombinant clone of E14-1 embryonic stem (ES) cells (129/OLA
lher.al deco.position of single hydroxychlorides of nickel. copper and cobalto
"... lhe thera¡.t! decoaposition reactions of Ni(OH)Cl.l~H20 dnd tl-C02(OH)3C1 and Y-Cu2(OH)3Cl in nitrogen ataosphere, TG analysis, and the interaediates and final products in still alr and in nitrogen have been studied by OlA and have been chdracterized by x-ray diffraction and infrared spectroscop,. l ..."
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lhe thera¡.t! decoaposition reactions of Ni(OH)Cl.l~H20 dnd tl-C02(OH)3C1 and Y-Cu2(OH)3Cl in nitrogen ataosphere, TG analysis, and the interaediates and final products in still alr and in nitrogen have been studied by OlA and have been chdracterized by x-ray diffraction and infrared spectroscop
Supplemental materials and methods
"... A BAC clone comprising exons 1–9 of Cd151 was isolated from a 129S6/SvEvTac library (RPCI-21; Invitrogen). An 8.8-kb fragment of genomic Cd151 was cloned in three steps into pFlexible, which is a generic targeting vector containing the selectable marker puroΔtk and loxP and frt recombination sites ( ..."
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I and NotI, 80 μg of the target construct were electroporated into 129/Ola-derived embryonic stem cells. Colonies resistant to 3.3 μM puromycin were screened for the desired homologous recombination by Southern blotting using a 5′-specific probe designed with primers P10 and P11. The puroΔtk cassette
www.PRSGlobalOpen.com 1
"... Achieving a natural-appearing nipple-areola complex (NAC) is an important component of breast reconstruction.1 The NAC is one of the most prominent landmarks of the breast and failure to accurately mirror any of the NAC charac-teristics will result in decreased patient satisfaction.1,2 Re-creation o ..."
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, Plainsboro, N.J.). In Figure 1, a breast is shown where the C-V nipple flap has been marked.3 After the flap is elevated and nipple reconstruction is completed, a circular line is drawn with the nipple located in its center. This is where the areola pe-riphery will appear once the breast and NAC have healed
Prostaglandin E2 Mediates Cough via the EP3 Receptor Implications for Future Disease Therapy
"... Abstract Rationale: A significant population of patients with severe asthma and chronic obstructive pulmonary disease is less responsive to β2-adrenoceptor agonists and corticosteroids, and there are possible safety issues concerning long-term use of these drugs. Inhaled prostaglandin E2 (PGE2) is ..."
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and prostanoid receptor-deficient mice, we provide substantial evidence that the EP3 receptor mediates PGE2-induced sensory nerve activation. Finally we provide in vivo proof of concept data demonstrating inhibition of PGE2-induced cough by a selective EP3 receptor antagonist. METHODS Animals Male C57BL/6 mice
