☯ These authors contributed equally to this work.

been used for problems ranging from tracking planes and missiles to predicting the economy. However, HMMs and KFMs are limited in their “expressive power”. Dynamic Bayesian Networks (DBNs) generalize HMMs by allowing the state space to be represented in factored form, instead of as a single discrete

restrictive assumptions can perform even better. In this paper we evaluate approaches for inducing classifiers from data, based on the theory of learning Bayesian networks. These networks are factored representations of probability distributions that generalize the naive Bayesian classifier and explicitly

Although Bayesian analysis has been in use since Laplace, the Bayesian method of model--comparison has only recently been developed in depth. In this paper, the Bayesian approach to regularisation and model--comparison is demonstrated by studying the inference problem of interpolating noisy data

A quantitative and practical Bayesian framework is described for learning of mappings in feedforward networks. The framework makes possible: (1) objective comparisons between solutions using alternative network architectures

This paper presents a Bayesian method for constructing probabilistic networks from databases. In particular, we focus on constructing Bayesian belief networks. Potential applications include computer-assisted hypothesis testing, automated scientific discovery, and automated construction

a unified variational Bayesian (VB) framework which approximates these computations in models with latent variables using a lower bound on the marginal likelihood. Chapter 1 presents background material on Bayesian inference, graphical models, and propaga-tion algorithms. Chapter 2 forms

inference scheme in a more general setting? We compare the marginals computed using loopy propagation to the exact ones in four Bayesian network architectures, including two real-world networks: ALARM and QMR. We find that the loopy beliefs often converge and when they do, they give a good

When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon

due to the lack of a systematic framework that can accommodate noise, variability, and low replication often typical of microarray data. Results: We develop a Bayesian probabilistic framework for microarray data analysis. At the simplest level, we model log-expression values by independent normal