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Multiobjectivization for Parameter Estimation: a CaseStudy on the Segment Polarity Network of Drosophila
"... Mathematical modeling for gene regulative networks (GRNs) provides an effective tool for hypothesis testing in biology. A necessary step in setting up such models is the estimation of model parameters, i.e., an optimization process during which the difference between model output and given experime ..."
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multiobjectivization can have on the optimization process. On the example of an established model for the segment polarity GRN in Drosophila, we test different multiobjectivization scenarios compared to a singleobjective function proposed earlier for the parameter optimization of the segment polarity network model
Mining the Network Value of Customers
 In Proceedings of the Seventh International Conference on Knowledge Discovery and Data Mining
, 2002
"... One of the major applications of data mining is in helping companies determine which potential customers to market to. If the expected pro t from a customer is greater than the cost of marketing to her, the marketing action for that customer is executed. So far, work in this area has considered only ..."
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Cited by 562 (11 self)
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only the intrinsic value of the customer (i.e, the expected pro t from sales to her). We propose to model also the customer's network value: the expected pro t from sales to other customers she may inuence to buy, the customers those may inuence, and so on recursively. Instead of viewing a market
Segmentation of brain MR images through a hidden Markov random field model and the expectationmaximization algorithm
 IEEE TRANSACTIONS ON MEDICAL. IMAGING
, 2001
"... The finite mixture (FM) model is the most commonly used model for statistical segmentation of brain magnetic resonance (MR) images because of its simple mathematical form and the piecewise constant nature of ideal brain MR images. However, being a histogrambased model, the FM has an intrinsic limi ..."
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Cited by 619 (14 self)
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The finite mixture (FM) model is the most commonly used model for statistical segmentation of brain magnetic resonance (MR) images because of its simple mathematical form and the piecewise constant nature of ideal brain MR images. However, being a histogrambased model, the FM has an intrinsic
Bayesian Network Classifiers
, 1997
"... Recent work in supervised learning has shown that a surprisingly simple Bayesian classifier with strong assumptions of independence among features, called naive Bayes, is competitive with stateoftheart classifiers such as C4.5. This fact raises the question of whether a classifier with less restr ..."
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Cited by 788 (23 self)
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Recent work in supervised learning has shown that a surprisingly simple Bayesian classifier with strong assumptions of independence among features, called naive Bayes, is competitive with stateoftheart classifiers such as C4.5. This fact raises the question of whether a classifier with less
Network Time Protocol (Version 3) Specification, Implementation and Analysis
, 1992
"... Note: This document consists of an approximate rendering in ASCII of the PostScript document of the same name. It is provided for convenience and for use in searches, etc. However, most tables, figures, equations and captions have not been rendered and the pagination and section headings are not ava ..."
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Cited by 522 (18 self)
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are not available. This document describes the Network Time Protocol (NTP), specifies its formal structure and summarizes information useful for its implementation. NTP provides the mechanisms to synchronize time and coordinate time distribution in a large, diverse internet operating at rates from mundane
Modeling and simulation of genetic regulatory systems: A literature review
 JOURNAL OF COMPUTATIONAL BIOLOGY
, 2002
"... In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between ..."
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Cited by 729 (15 self)
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DNA, RNA, proteins, and small molecules. As most genetic regulatory networks of interest involve many components connected through interlocking positive and negative feedback loops, an intuitive understanding of their dynamics is hard to obtain. As a consequence, formal methods and computer tools
Fusion, Propagation, and Structuring in Belief Networks
 ARTIFICIAL INTELLIGENCE
, 1986
"... Belief networks are directed acyclic graphs in which the nodes represent propositions (or variables), the arcs signify direct dependencies between the linked propositions, and the strengths of these dependencies are quantified by conditional probabilities. A network of this sort can be used to repre ..."
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Cited by 482 (8 self)
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Belief networks are directed acyclic graphs in which the nodes represent propositions (or variables), the arcs signify direct dependencies between the linked propositions, and the strengths of these dependencies are quantified by conditional probabilities. A network of this sort can be used
A simple method for displaying the hydropathic character of a protein
 Journal of Molecular Biology
, 1982
"... A computer program that progressively evaluates the hydrophilicity and hydrophobicity of a protein along its amino acid sequence has been devised. For this purpose, a hydropathy scale has been composed wherein the hydrophilic and hydrophobic properties of each of the 20 amino acid sidechains is tak ..."
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Cited by 2249 (2 self)
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chains is taken into consideration. The scale is based on an amalgam of experimental observations derived from the literature. The program uses a movingsegment approach that continuously determines the average hydropathy within a segment of predetermined length as it advances through the sequence
Bundle Adjustment  A Modern Synthesis
 VISION ALGORITHMS: THEORY AND PRACTICE, LNCS
, 2000
"... This paper is a survey of the theory and methods of photogrammetric bundle adjustment, aimed at potential implementors in the computer vision community. Bundle adjustment is the problem of refining a visual reconstruction to produce jointly optimal structure and viewing parameter estimates. Topics c ..."
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Cited by 555 (12 self)
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This paper is a survey of the theory and methods of photogrammetric bundle adjustment, aimed at potential implementors in the computer vision community. Bundle adjustment is the problem of refining a visual reconstruction to produce jointly optimal structure and viewing parameter estimates. Topics
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