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PROBIOTICS FOR THE PREVENTION OF PEDIATRIC ANTIBIOTIC-ASSOCIATED DIARRHEA

by Johnston Bradley , Vandvik Per O Joshua Z Goldenberg , Sun Xin , Guyatt Gordon , H Johnston , Bradley C Goldenberg , Vandvik Per O Joshua Z , Sun Xin , Guyatt Gordon
"... A B S T R A C T Background Antibiotics alter the microbial balance within the gastrointestinal tract. Probiotics may prevent antibiotic-associated diarrhea (AAD) via restoration of the gut microflora. Antibiotics are prescribed frequently in children and AAD is common in this population. Objective ..."
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, indicated limited differences between the relative risk and corresponding 95% confidence intervals. Nonetheless, because the I2 statistic demonstrated moderate heterogeneity within and between studies, a random-effects model was used for all statistical analyses. Imputation for missing data analysis
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