, and make recommendations for research and practice. In spite of general decreases in the prevalence of the nonmed-ical use of most legal and illegal drugs in recent years, the abuse of alcohol and other drugs during adolescence and early adulthood remains a serious public health problem (Adams, Blanken

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With the significant advances in Information and Communications Technology (ICT) over the last half century, there is an increasingly perceived vision that computing will one day be the 5th utility (after water, electricity, gas, and telephony). This computing utility, like all other four existing utilities, will provide the basic level of computing service that is considered essential to meet the everyday needs of the general community. To deliver this vision, a number of computing paradigms have been proposed, of which the latest one is known as Cloud computing. Hence, in this paper, we define Cloud computing and provide the architecture for creating Clouds with market-oriented resource allocation by leveraging technologies such as Virtual Machines (VMs). We also provide insights on market-based resource management strategies that encompass both customer-driven service management and computational risk management to sustain Service Level Agreement (SLA)-oriented resource allocation. In addition, we reveal our early thoughts on interconnecting Clouds for dynamically creating global Cloud exchanges and markets. Then, we present some representative Cloud platforms, especially those developed in industries along with our current work towards realizing market-oriented resource allocation of Clouds as realized in Aneka enterprise Cloud technology. Furthermore, we highlight the difference between High Performance Computing (HPC) workload and Internet-based services workload. We also describe a meta-negotiation infrastructure to establish global Cloud

This paper is intended to serve as a comprehensive introduction to the emerging field concerned with the design and use of ontologies. We observe that disparate backgrounds, languages, tools, and techniques are a major barrier to effective communication among people, organisations, and/or software systems. We show how the development and implementation of an explicit account of a shared understanding (i.e. an `ontology') in a given subject area, can improve such communication, which in turn, can give rise to greater reuse and sharing, inter-operability, and more reliable software. After motivating their need, we clarify just what ontologies are and what purposes they serve. We outline a methodology for developing and evaluating ontologies, first discussing informal techniques, concerning such issues as scoping, handling ambiguity, reaching agreement and producing de nitions. We then consider the bene ts of and describe, a more formal approach. We re-visit the scoping phase, and discuss the role of formal languages and techniques in the specification, implementation and evaluation of ontologies. Finally, we review the state of the art and practice in this emerging field,

Since 1973 technological, political, regulatory, and economic forces have been changing the worldwide economy in a fashion comparable to the changes experienced during the nineteenth century Industrial Revolution. As in the nineteenth century, we are experiencing declining costs, increaing average (but decreasing marginal) productivity of labor, reduced growth rates of labor income, excess capacity, and the requirement for downsizing and exit. The last two decades indicate corporate internal control systems have failed to deal effectively with these changes, especially slow growth and the requirement for exit. The next several decades pose a major challenge for Western firms and political systems as these forces continue to work their way through the worldwide economy.

El Salvador, Guatemala is a, study in black and white. On the left is a collection of extreme Marxist-Leninist groups led by what one diplomat calls “a pretty faceless bunch of people.’ ’ On the right is an entrenched elite that has dominated Central America’s most populous country since a CIA-backed coup deposed the reformist government of Col. Jacobo Arbenz Guzmán in 1954. Moderates of the political center. embattled but alive in E1 Salvador, have virtually disappeared in Guatemala-joining more than 30.000 victims of terror over the last tifteen vears. “The situation in Guatemala is much more serious than in EI Salvador, ” declares one Latin American diplomat. “The oligarchy is that much more reactionary. and the choices are far fewer. “ ‘Zero’: The Guatemalan oligarchs hated Jimmy Carter for cutting off U.S. military aid in 1977 to protest human-rights abuses-and the right-wingers hired marimba bands and set off firecrackers on the night Ronald Reagan was elected. They considered Reagan an ideological kinsman and believed they had a special

While the benefits of bank financing are relatively well understood, the costs are not. This paper argues that while informed banks make flexible financial decisions which prevent a firm's projects from going awry, the cost of this credit is that banks have bargaining power over the firm's profits, once projects have begun. The firm's portfolio choice of borrowing source and the choice of priority for its debt claims attempt to optimally circumscribe the powers of banks.

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I develop a general equilibrium model with sticky prices, credit constraints, nominal loans and asset prices. Changes in asset prices modify agents ’ borrowing capacity through collateral value; changes in nominal prices affect real repayments through debt deflation. Monetary policy shocks move asset and nominal prices in the same direction, and are amplified and propagated over time. The “financial accelerator ” is not constant across shocks: nominal debt stabilises supply shocks, making the economy less volatile when the central bank controls the interest rate. I discuss the role of equity, debt indexation and household and firm leverage in the propagation mechanism. Finally, I find that monetary policy should not target asset prices as a means of reducing output and inflation volatility.

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