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87
Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques
, 1996
"... We used the simian immunodeficiency virus (SIV)/rhesus macaque model to study events that underlie sexual transmission of human inununodeficiency virus type 1 (HIV-1). Four female rhesus macaques were inoculated intravaginally with SIVmac251, and then killed 2, 5, 7, and 9 d later. A technique that ..."
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Cited by 96 (9 self)
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We used the simian immunodeficiency virus (SIV)/rhesus macaque model to study events that underlie sexual transmission of human inununodeficiency virus type 1 (HIV-1). Four female rhesus macaques were inoculated intravaginally with SIVmac251, and then killed 2, 5, 7, and 9 d later. A technique
SECURITY BREACH IN TRADING SYSTEM- COUNTERMEASURE USING IPTRACEBACK
"... Recently, economic scenario is often facing security breach that has heavy impact on the financial soundness of a company particularly, stock prices on firms. The utmost consequence being the whole business comes to a standstill. From the estimates attributed by the financial sector, it has been inf ..."
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inferred that the loss incurred on virus and worms attack is said to have the greatest impact that hampers the prosperity of a business entity. Thus, security strategies attempt on revolving around the act of security breach, thereby targeting to curb the financial losses of a company totally or at least
Simian Immunodeficiency Virus Infection Induces Expansion
, 2010
"... Herein we demonstrate that chronic simian immunodeficiency virus (SIV) infection induces significant upregulation of the gut-homing marker 47 on macaque NK cells, coupled with downregulation of the lymph node-trafficking marker, CCR7. Interestingly, in naïve animals, 47 expression was associated wit ..."
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Herein we demonstrate that chronic simian immunodeficiency virus (SIV) infection induces significant upregulation of the gut-homing marker 47 on macaque NK cells, coupled with downregulation of the lymph node-trafficking marker, CCR7. Interestingly, in naïve animals, 47 expression was associated
A natural model of Leishmania major infection reveals a prolonged “silent” phase of parasite amplification in the skin before the onset of lesion formation and immunity
, 2000
"... A model of Leishmania major infection in C57BL/6 mice has been established that combines two main features of natural transmission: low dose (100 metacyclic promastigotes) and inoculation into a dermal site (the ear dermis). The evolution of the dermal lesion could be dissociated into two distinct p ..."
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Cited by 79 (19 self)
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of neutrophils, macrophages, and eosinophils into the dermis and was coincident with the killing of parasites in the site. The onset of immunity/pathology was correlated with the appearance of cells staining for IL-12p40 and IFN- � in the epidermal compartment, and an expansion of T cells capable of producing
Rates of ctl killing in persistent viral infection in vivo
- PLoS Comput. Biol
"... The CD8+ cytotoxic T lymphocyte (CTL) response is an important defence against viral invasion. Although CTL-mediated cytotoxicity has been widely studied for many years, the rate at which virus-infected cells are killed in vivo by the CTL response is poorly understood. To date the rate of CTL killin ..."
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Cited by 1 (1 self)
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of killing of infected cells by CD8+ T cells in two distinct persistent virus infections: sheep infected with Bovine Leukemia Virus (BLV) and humans infected with Human T Lymphotropic Virus type 1 (HTLV-1) which together with existing data allows us to study a total of five viruses in parallel. Although both
On Cellular Botnets: Measuring the Impact of Malicious Devices on a Cellular Network Core
- In Proc. 16th Conference on Computer and Communications Security
, 2009
"... The vast expansion of interconnectivity with the Internet and the rapid evolution of highly-capable but largely insecure mobile devices threatens cellular networks. In this paper, we characterize the impact of the large scale compromise and coordination of mobile phones in attacks against the core o ..."
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Cited by 59 (5 self)
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and not a constant stream of phone calls, users are unlikely to be aware of their occurrence. We then investigate a number of significant network bottlenecks, their impact on the density of compromised nodes per base station and how they can be avoided. We conclude by discussing a number of countermeasures
Neonatal Deletion and Selective Expansion of Mouse T Cells by Exposure to Rabies Virus
"... The nucleocapsid (NC) of the rabies virus behaves as an exogenous superantigen (SAg) in humans. In the present report, we analyzed whether it is also a SAg in mice by studying the effect of NC on T cell receptor (TCR) VB expression in BALB/c mice. Repeated injection of NC in newborn BALB/c mice led ..."
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The nucleocapsid (NC) of the rabies virus behaves as an exogenous superantigen (SAg) in humans. In the present report, we analyzed whether it is also a SAg in mice by studying the effect of NC on T cell receptor (TCR) VB expression in BALB/c mice. Repeated injection of NC in newborn BALB/c mice led
Clonal Expansion of Normal-Appearing Human Hepatocytes during Chronic Hepatitis B Virus Infection†
, 2010
"... Chronic hepatitis B virus (HBV) infections are associated with persistent immune killing of infected hepatocytes. Hepatocytes constitute a largely self-renewing population. Thus, immune killing may exert selec-tive pressure on the population, leading it to evolve in order to survive. A gradual cours ..."
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Chronic hepatitis B virus (HBV) infections are associated with persistent immune killing of infected hepatocytes. Hepatocytes constitute a largely self-renewing population. Thus, immune killing may exert selec-tive pressure on the population, leading it to evolve in order to survive. A gradual
Monkeypox virus infection of rhesus macaques induces massive expansion of natural killer cells but suppresses natural killer cell functions
"... Natural killer (NK) cells play critical roles in innate immunity and in bridging innate and adaptive immune responses against viral infection. However, the response of NK cells to monkeypox virus (MPXV) infection is not well characterized. In this intravenous challenge study of MPXV infection in rhe ..."
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Cited by 1 (0 self)
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in rhesus macaques (Macaca mulatta), we analyzed blood and lymph node NK cell changes in absolute cell numbers, cell proliferation, chemokine receptor expression, and cellular functions. Our results showed that the absolute number of total NK cells in the blood increased in response to MPXV infection at a
Survival and Clonal Expansion of Mutating “Forbidden” (Immunoglobulin Receptor–deficient) Epstein-Barr Virus–
"... Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a peculiar T cell lymphoma, as expanding B cell clones are often present besides the malignant T cell clones. In addition, large numbers of Epstein-Barr virus (EBV)-infected B cells are frequently observed. To analyze the differentiati ..."
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Cited by 2 (0 self)
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Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a peculiar T cell lymphoma, as expanding B cell clones are often present besides the malignant T cell clones. In addition, large numbers of Epstein-Barr virus (EBV)-infected B cells are frequently observed. To analyze
Results 1 - 10
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87
