vaginal transmission of a TFV‑resistant SHIV containing the K65R mutation (SHIV162P3K65R) and its relationship to drug levels in vaginal tissues. Results: SHIV162P3K65R shows approximately a 5‑fold reduction in susceptibility to TFV compared to wild‑type SHIV. Efficacy was evaluated in pig‑tailed macaques

should be explored. Here we developed and compared combinatorial foamy virus (FV) anti-HIV vectors that also express a mutant methylguanine methyltransferase (MGMTP140K) transgene to increase the percentage of gene modified cells after transplantation. These FV vectors inhibit replication of HIV-1

physics pp. 951–961 Cosmic microwave background radiation anisotropies and data analysis SHIV K SETHI

Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection

In vivo passage of a chimeric simian-human immunodeficiency virus (SHIV-89.6) expressing the human immunodeficiency virus type 1 (HIV-1) tat, rev, vpu, and env genes generated pathogenic viruses (SHIV-89.6P) inducing rapid CD41 lymphocyte depletion and AIDS-like illness in rhesus monkeys (K

(Article begins on next page) The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters. Citation Watkins, Jennifer D., Nagadenahalli B. Siddappa, Samir K.Lakhashe, Michael Humbert, Anton Sholukh, Girish Hemashettar, Yin Ling Wong

Shri V.K. Joshi, and Dr. R.D. Sharma during a discussion Every year Vigyan Prasar organises Hindi Pakhwara during the period 15-30September 2006. During this period a variety of competit ions and programmes are organized for its members. On 15 September 2006, a workshop on popular science writing

frommacaques infected with an SIV variant containing HIV-1 reverse transcriptase (RT) (RT-simian-human immunodeficiency [SHIV]mne), before and after they were exposed to a short course of efavirenz (EFV) monotherapy. We detected RT inhibitor (RTI) resistance mutations K65R andM184I but not K103N in 2 of 2 RT-SHIV

of this approach. Here we evaluated HSC gene transfer of an anti-HIV vector in the pigtailed macaque (Macaca nemestrina) model, which closely models human transplantation. Methods and Findings: We used lentiviral vectors that inhibited both HIV-1 and simian immunodeficiency virus (SIV)/HIV-1 (SHIV) chimera virus

Postmodern Indian English poetry is the result of many experiments, new themes, techniques, personal experience, irony, maximalism, pastiche and above all rejection of romantic and melodious style and rhythm. So many poets like Jayanta Mahapatra, A.K.Ramanujan, Kamala Das, Shiv.K.Kumar, Gieve Patel