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Quality control in the secretory pathway: retention of a misfolded viral membrane glycoprotein involves cycling between the ER, intermediate compartment, and Golgi apparatus
- J. Cell
, 1994
"... Abstract. Proteins synthesized in the ER are generally transported to the Golgi complex and beyond only when they have reached a fully folded and assembled conformation. To analyze how the selective retention of misfolded proteins works, we monitored the longterm fate of a membrane glycoprotein with ..."
Abstract
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Cited by 159 (6 self)
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Abstract. Proteins synthesized in the ER are generally transported to the Golgi complex and beyond only when they have reached a fully folded and assembled conformation. To analyze how the selective retention of misfolded proteins works, we monitored the longterm fate of a membrane glycoprotein
The clathrin endocytic pathway in viral infection
- EMBO J
, 1998
"... How important is the clathrin-dependent endocytic pathway for entry of viruses into host cells? While it is widely accepted that Semliki Forest virus (SFV), an enveloped virus, requires this pathway there are conflicting data concerning the closely related Sindbis virus, as well as varying results w ..."
Abstract
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Cited by 77 (1 self)
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How important is the clathrin-dependent endocytic pathway for entry of viruses into host cells? While it is widely accepted that Semliki Forest virus (SFV), an enveloped virus, requires this pathway there are conflicting data concerning the closely related Sindbis virus, as well as varying results
• VIRAL HEPATITIS •
"... AIM: To evaluate the expression of f ibr inogen-like protein 2 (fgl2) and its correlation with disease progression in both mice and patients with severe viral hepatitis. METHODS: Ba lb/cJ or A/J mice were in fected intraperitoneally (ip) with 100 PFU of murine hepatitis virus type 3 (MHV-3), liver a ..."
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AIM: To evaluate the expression of f ibr inogen-like protein 2 (fgl2) and its correlation with disease progression in both mice and patients with severe viral hepatitis. METHODS: Ba lb/cJ or A/J mice were in fected intraperitoneally (ip) with 100 PFU of murine hepatitis virus type 3 (MHV-3), liver
Viral information
, 2012
"... The Author(s) 2012. This article is published with open access at Springerlink.com Abstract Viruses are major drivers of global biogeochemistry and the etiological agents of many diseases. They are also the winners in the game of life: there are more viruses on the planet than cellular organisms an ..."
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in nature). Finally, we show how viral information can be tested, and illustrate how this novel view can explain existing ecological and evolutionary theories from more fundamental principles.
Virality 1 Social Transmission and Viral Culture
"... conference, and the University of Chicago for helpful comments on a prior version of the manuscript. The Wharton Interactive Media Initiative helped fund this research. Virality 2 People often share news, opinions, and information, and social transmission shapes both individual behavior and collecti ..."
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. The magnitudes of these relationships are considerable. These results underscore the importance of considering how individual-level psychological processes shape collective outcomes such as the transmission and prominence of culture. KEYWORDS: Social Transmission, Word-of-Mouth, Social EpidemicsVirality 3
Viral chemokine-binding proteins
- J. Leukoc
, 2002
"... Abstract: The chemokines are a large family of small signaling proteins that bind to G-protein-coupled receptors (GPCRs) on target cells and mediate the directional migration of immune cells into sites of infection or inflammation. The large DNA viruses, particularly the poxviruses and herpesviruses ..."
Abstract
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Cited by 9 (0 self)
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by poxviruses and herpesviruses. A better understanding of how viral CKBPs function to manipulate the immune response may provide further clues as to how to develop specific therapeutic agents to abrogate chemokine-mediated disease conditions. J. Leukoc. Biol. 72:
Evolving viral marketing strategies
- In GECCO ’10: Proceedings of the 12th annual conference on genetic and evolutionary computation
, 2010
"... One method of viral marketing involves seeding certain consumers within a population to encourage faster adoption of the product throughout the entire population. However, determining how many and which consumers within a particular social network should be seeded to maximize adoption is challenging ..."
Abstract
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Cited by 6 (2 self)
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One method of viral marketing involves seeding certain consumers within a population to encourage faster adoption of the product throughout the entire population. However, determining how many and which consumers within a particular social network should be seeded to maximize adoption
A Measurement-driven Analysis of Information Propagation in the Flickr Social Network
"... Online social networking sites like MySpace, Facebook, and Flickr have become a popular way to share and disseminate content. Their massive popularity has led to viral marketing techniques that attempt to spread content, products, and ideas on these sites. However, there is little data publicly avai ..."
Abstract
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Cited by 151 (3 self)
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available on viral propagation in the real world and few studies have characterized how information spreads over current online social networks. In this paper, we collect and analyze large-scale traces of information dissemination in the Flickr social network. Our analysis, based on crawls of the favorite
ABSTRACT The Dynamics of Viral Marketing ∗
"... We present an analysis of a person-to-person recommendation network, consisting of 4 million people who made 16 million recommendations on half a million products. We observe the propagation of recommendations and the cascade sizes, which we explain by a simple stochastic model. We then establish ho ..."
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how the recommendation network grows over time and how effective it is from the viewpoint of the sender and receiver of the recommendations. While on average recommendations are not very effective at inducing purchases and do not spread very far, we present a model that successfully identifies product
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