Results 1 - 10 of 2,101

Measurements and analysis of end-to-end Internet dynamics

by Vern Paxson , 1997
"... ..."
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Abstract not found

Linear Programming: Foundations and Extensions

by Robert J. Vanderbei , 1996
"... under the United States Copyright Act of 1976, no part of this publication may be reproduced or distributed in any form or by any means, or stored in a data base or retrieval system, without the prior written permission of the publisher. ISBN 0-0000-0000-0 The text for this book was formated in Time ..."
Abstract - Cited by 196 (0 self) - Add to MetaCart
in Times-Roman and the mathematics was formated in Michael Spivak’s Mathtimes using AMS-L ATEX(which is a macro package for Leslie Lamport’s L ATEX, which itself is a macro package for Donald Knuth’s TEXtext formatting system) and converted from device-independent to postscript format using DVIPS. The fig

High-Performance Haplotype Assembly

by Marco Aldinucci, Andrea Bracciali, Tobias Marschall, Murray Patterson, Nadia Pisanti, Massimo Torquati
"... Abstract. The problem of Haplotype Assembly is an essential step in human genome analysis. It is typically formalised as the Minimum Error Correction (MEC) problem which is NP-hard. MEC has been approached using heuristics, integer linear programming, and fixed-parameter tractability (FPT), includin ..."
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Abstract. The problem of Haplotype Assembly is an essential step in human genome analysis. It is typically formalised as the Minimum Error Correction (MEC) problem which is NP-hard. MEC has been approached using heuristics, integer linear programming, and fixed-parameter tractability (FPT

A Next-Generation Sequencing Method for Genotyping- by-Sequencing of Highly Heterozygous Autotetraploid Potato

by Anne-marie A. Wolters, Bjorn B. D’hoop, Theo J. A. Borm, Richard G. F. Visser, Herman J. Van Eck
"... Assessment of genomic DNA sequence variation and genotype calling in autotetraploids implies the ability to distinguish among five possible alternative allele copy number states. This study demonstrates the accuracy of genotyping-by-sequencing (GBS) of a large collection of autotetraploid potato cul ..."
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Assessment of genomic DNA sequence variation and genotype calling in autotetraploids implies the ability to distinguish among five possible alternative allele copy number states. This study demonstrates the accuracy of genotyping-by-sequencing (GBS) of a large collection of autotetraploid potato

THEORY AND ALGORITHMS FOR THE HAPLOTYPE ASSEMBLY PROBLEM

by Russell Schwartz , 2010
"... Genome sequencing studies to date have generally sought to assemble consensus genomes by merging sequence contributions from multiple homologous copies of each chromosome. With growing interest in genetic variations, however, there is a need for methods to separate these distinct contributions and ..."
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as the “haplotype assembly ” problem. This review paper surveys results on the theory and algorithms for haplotype assembly. It first describes common abstractions of the problem. It then discusses some notable intractibility results for different problem variants. It next examines a variety of combinatorial

Y: Haplotype inference by maximum parsimony

by Lusheng Wang, Ying Xu - Bioinformatics
"... Motivation: Haplotypes have been attracting increasing attention because of their importance in analysis of many fine-scale molecular-genetics data. Since direct sequencing of haplotype via experimental methods is both time-consuming and expensive, haplotype inference methods that infer haplotypes b ..."
Abstract - Cited by 67 (4 self) - Add to MetaCart
samples. (2) Strong supports of this computational model are given based on the computational results on both real data and simulation data. (3) We also did some comparative study to show the strength and weakness of this computational model using our program. Availability: The software HAPAR is free

OrIGInAl PAPer QTL mapping in autotetraploids using SNP dosage information

by Glenn J. Bryan
"... © The Author(s) 2014. This article is published with open access at Springerlink.com heritability from a potato population of 190 F1 individuals: flower colour, maturity, height and resistance to late blight (Phytophthora infestans (Mont.) de Bary) and potato cyst nematode (Globodera pallida), using ..."
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© The Author(s) 2014. This article is published with open access at Springerlink.com heritability from a potato population of 190 F1 individuals: flower colour, maturity, height and resistance to late blight (Phytophthora infestans (Mont.) de Bary) and potato cyst nematode (Globodera pallida

Haplotype Inference by Pure Parsimony with Constraint Programming

by Xiaoyue Pan, Xiaoyue Pan , 2009
"... Haplotype inference by pure parsimony problem (HIPP) is a computational problem in bioinformatics. It is a relatively new NP-hard problem and it has been thoroughly explored using integer programming, SAT-based programming and answer set programming. The state of the art approach is the SAT-based mo ..."
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Haplotype inference by pure parsimony problem (HIPP) is a computational problem in bioinformatics. It is a relatively new NP-hard problem and it has been thoroughly explored using integer programming, SAT-based programming and answer set programming. The state of the art approach is the SAT

An Autotetraploid Linkage Map of Rose (Rosa hybrida) Validated Using the Strawberry (Fragaria vesca) Genome Sequence

by Oron Gar, Daniel J. Sargent, Ching-jung Tsai, Tzili Pleban, Gil Shalev, David H. Byrne, Dani Zamir , 2011
"... Polyploidy is a pivotal process in plant evolution as it increase gene redundancy and morphological intricacy but due to the complexity of polysomic inheritance we have only few genetic maps of autopolyploid organisms. A robust mapping framework is particularly important in polyploid crop species, r ..."
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, rose included (2n =4x = 28), where the objective is to study multiallelic interactions that control traits of value for plant breeding. From a cross between the garden, peach red and fragrant cultivar Fragrant Cloud (FC) and a cut-rose yellow cultivar Golden Gate (GG), we generated an autotetraploid

Models and Algorithms for Haplotyping Problem

by Xiang-sun Zhang, Rui-sheng Wang, Ling-yun Wu, Luonan Chen - Current Bioinformatics , 2006
"... Abstract: One of the main topics in genomics is to determine the relevance of DNA variations with some genetic disease. Single nucleotide polymorphism (SNP) is the most frequent and important form of genetic variation which involves a single DNA base. The values of a set of SNPs on a particular chro ..."
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chromosome copy define a haplotype. Because of its importance in the studies of complex disease association, haplotyping is one of the central problems in bioinformatics. There are two classes of in silico haplotyping problems, i.e., single individual haplotyping and population haplotyping. In this review
Results 1 - 10 of 2,101