Results 1  10
of
3,482,833
Fast Folding and Comparison of RNA Secondary Structures (The Vienna RNA Package)
"... Computer codes for computation and comparison of RNA secondary structures, the Vienna RNA package, are presented, that are based on dynamic programming algorithms and aim at predictions of structures with minimum free energies as well as at computations of the equilibrium partition functions and bas ..."
Abstract

Cited by 812 (119 self)
 Add to MetaCart
and base pairing probabilities. An efficient heuristic for the inverse folding problem of RNA is introduced. In addition we present compact and efficient programs for the comparison of RNA secondary structures based on tree editing and alignment. All computer codes are written in ANSI C. They include
Specificity and mechanism of action of some commonly used protein kinase inhibitors
 Biochem. J
, 2000
"... The specificities of 28 commercially available compounds reported to be relatively selective inhibitors of particular serine� threoninespecific protein kinases have been examined against a large panel of protein kinases. The compounds KT 5720, Rottlerin and quercetin were found to inhibit many prot ..."
Abstract

Cited by 514 (1 self)
 Add to MetaCart
or more protein kinases with similar potency. LY 294002 was found to inhibit casein kinase2 with similar potency to phosphoinositide (phosphatidylinositol) 3kinase. The compounds with the most
2005 MAFFT version 5: improvement in accuracy of multiple sequence alignment. Nucleic Acids Res
"... The accuracy of multiple sequence alignment program MAFFT has been improved. The new version (5.3) of MAFFT offers new iterative refinement options, HINSi, FINSi and GINSi, in which pairwise alignment information are incorporated into objective function. These new options of MAFFT showed hig ..."
Abstract

Cited by 788 (5 self)
 Add to MetaCart
The accuracy of multiple sequence alignment program MAFFT has been improved. The new version (5.3) of MAFFT offers new iterative refinement options, HINSi, FINSi and GINSi, in which pairwise alignment information are incorporated into objective function. These new options of MAFFT showed
Homological Algebra of Mirror Symmetry
 in Proceedings of the International Congress of Mathematicians
, 1994
"... Mirror Symmetry was discovered several years ago in string theory as a duality between families of 3dimensional CalabiYau manifolds (more precisely, complex algebraic manifolds possessing holomorphic volume elements without zeroes). The name comes from the symmetry among Hodge numbers. For dual Ca ..."
Abstract

Cited by 529 (3 self)
 Add to MetaCart
CalabiYau manifolds V, W of dimension n (not necessarily equal to 3) one has dim H p (V, Ω q) = dim H n−p (W, Ω q). Physicists conjectured that conformal field theories associated with mirror varieties are equivalent. Mathematically, MS is considered now as a relation between numbers of rational curves
Numerical integration of the Cartesian equations of motion of a system with constraints: molecular dynamics of nalkanes
 J. Comput. Phys
, 1977
"... A numerical algorithm integrating the 3N Cartesian equations of motion of a system of N points subject to holonomic constraints is formulated. The relations of constraint remain perfectly fulfilled at each step of the trajectory despite the approximate character of numerical integration. The method ..."
Abstract

Cited by 682 (6 self)
 Add to MetaCart
(MD), which has been widely used in the past for studying simple liquids and solids, has more recently been applied to molecular systems with internal degrees of freedom such as N, [l], H,O [2] and even C,H,, [3]. In applying the MD method three problems arise: (a) the choice of a suitable mechanical
The Complete Atomic Structure of the Large Ribosomal Subunit at 2.4 Å Resolution
 Science
, 2000
"... ation, and termination phases of protein synthesis. Because the structures of several DNA and RNA polymerases have been determined at atomic resolution, the mechanisms of DNA and RNA synthesis are both well understood. Determination of the structure of the ribosome, however, has proven a daunting t ..."
Abstract

Cited by 529 (13 self)
 Add to MetaCart
ation, and termination phases of protein synthesis. Because the structures of several DNA and RNA polymerases have been determined at atomic resolution, the mechanisms of DNA and RNA synthesis are both well understood. Determination of the structure of the ribosome, however, has proven a daunting
Dictionary of protein secondary structure: pattern recognition of hydrogenbonded and geometrical features
 Biopolymers
, 1983
"... structure ..."
Concurrent Constraint Programming
, 1993
"... This paper presents a new and very rich class of (concurrent) programming languages, based on the notion of comput.ing with parhal information, and the concommitant notions of consistency and entailment. ’ In this framework, computation emerges from the interaction of concurrently executing agent ..."
Abstract

Cited by 502 (16 self)
 Add to MetaCart
This paper presents a new and very rich class of (concurrent) programming languages, based on the notion of comput.ing with parhal information, and the concommitant notions of consistency and entailment. ’ In this framework, computation emerges from the interaction of concurrently executing
A Theory of Diagnosis from First Principles
 ARTIFICIAL INTELLIGENCE
, 1987
"... Suppose one is given a description of a system, together with an observation of the system's behaviour which conflicts with the way the system is meant to behave. The diagnostic problem is to determine those components of the system which, when assumed to be functioning abnormally, will explain ..."
Abstract

Cited by 1117 (5 self)
 Add to MetaCart
Suppose one is given a description of a system, together with an observation of the system's behaviour which conflicts with the way the system is meant to behave. The diagnostic problem is to determine those components of the system which, when assumed to be functioning abnormally
Regression Shrinkage and Selection Via the Lasso
 Journal of the Royal Statistical Society, Series B
, 1994
"... We propose a new method for estimation in linear models. The "lasso" minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant. Because of the nature of this constraint it tends to produce some coefficients that are exactl ..."
Abstract

Cited by 4055 (51 self)
 Add to MetaCart
We propose a new method for estimation in linear models. The "lasso" minimizes the residual sum of squares subject to the sum of the absolute value of the coefficients being less than a constant. Because of the nature of this constraint it tends to produce some coefficients
Results 1  10
of
3,482,833