a geospatial surveillance pathogen database

Abstract. Semantic sensor networks use declarative descriptions of sen-sors promote reuse and integration, and to help solve the difficulties of installing, querying and maintaining complex, heterogeneous sensor net-works. This paper reviews the state of the art for the semantic specifi-cation of sensors, one of the fundamental technologies in the semantic sensor network vision. Twelve sensor ontologies are reviewed and anal-ysed for the range and expressive power of their concepts. The reasoning and search technology developed in conjunction with these ontologies is also reviewed, as is technology for annotating OGC standards with links to ontologies. Sensor concepts that cannot be expressed accurately by current sensor ontologies are also discussed. 1

The molecular basis ofthe pathogenicity of in-fectious agents, and of the corresponding mechanisms of host defence, can be studied using model systems1. Intui-tively, the more closely related a model of an infectious dis-ease is to the natural pathol-ogy, the greater its relevance, hence

Background: Mosquito-borne infectious diseases pose a severe threat to public health in many areas of the world. Current methods for pathogen detection and surveillance are usually dependent on prior knowledge of the etiologic agents involved. Hence, efficient approaches are required for screening

°C in the first 3 cycles, then 3°C in the second 3 cycles, followed by 30 cycles at 48°C. In each cycle, denaturing (at 94°C) and annealing (at 54 -48°C) were 20 s, and extensions (at 68°C) were 60 s in duration. An initial 2-min denaturation and a final 6-min extension step were also included. PCR

of proteins present in a given tissue or fluid (the proteome). It is of significant importance to numerous scientific areas, including animal and veterinary sciences. Despite this, proteomics has been limited in these disciplines due to a number of reasons, including cost, lack of good genomic data from many

strategies were developed (36). Coupling the two techniques for all V domain-C region combinations provides a complete qualitative and quantitative picture of the repertoire (37-39) described by up to 2,000 measurements per IG isotype or TR for one sample. With the development of real-time quantitative PCR