Tools
Sorted by:
Try your query at:
 |
 |
 |
 |
 |
 |
Results 1 - 10
of
9,871
RESEARCH Open Access Agent based modeling of Treg-Teff cross regulation in relapsing-remitting multiple sclerosis
"... Background: Multiple sclerosis (MS) is a disease of central nervous system that causes the removal of fatty myelin sheath from axons of the brain and spinal cord. Autoimmunity plays an important role in this pathology outcome and body’s own immune system attacks on the myelin sheath causing the dama ..."
Abstract
- Add to MetaCart
conditions such as a breakdown of the mechanisms that regulate and allow peripheral tolerance should be involved. Conclusions: The presented model allows to capture the essential dynamics of relapsing-remitting MS despite its simplicity. It gave useful insights that support the hypothesis of a breakdown
relapsing-remitting multiple sclerosis
"... Background: Numerous cytokines are implicated in the immunopathogenesis of multiple sclerosis (MS), but studies are often limited to whole blood (WB) or peripheral blood mononuclear cells (PBMCs), thereby omitting important information about the cellular origin of the cytokines. Knowledge about the ..."
Abstract
- Add to MetaCart
the relation between blood and cerebrospinal fluid (CSF) cell expression of cytokines and the cellular source of CSF cytokines is even more scarce. Methods: We studied gene expression of a broad panel of cytokines in WB from relapsing-remitting multiple sclerosis (RRMS) patients in remission and healthy
Longitudinal Change in Physical Activity and Its Correlates in Relapsing-Remitting Multiple Sclerosis
"... Background. Physical activity is beneficial for people with multiple sclerosis (MS), but this population is largely inactive. There is minimal information on change in physical activity and its correlates for informing the development of behavioral interventions. Objective. This study examined chang ..."
Abstract
-
Cited by 1 (0 self)
- Add to MetaCart
change in physical activity and its symptomatic, social-cognitive, and ambulatory or disability correlates over a 2.5-year period of time in people with relapsing-remitting multiple sclerosis. Methods. On 6 occasions, each separated by 6 months, people (N269) with relapsing-remitting multiple sclerosis
Reassessment of Blood Gene Expression Markers for the Prognosis of Relapsing-Remitting Multiple Sclerosis
"... Despite considerable advances in the treatment of multiple sclerosis, current drugs are only partially effective. Most patients show reduced disease activity with therapy, but still experience relapses, increasing disability, and new brain lesions. Since there are no reliable clinical or biological ..."
Abstract
- Add to MetaCart
Despite considerable advances in the treatment of multiple sclerosis, current drugs are only partially effective. Most patients show reduced disease activity with therapy, but still experience relapses, increasing disability, and new brain lesions. Since there are no reliable clinical or biological
Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. Circulation
, 1999
"... The online version of this article, along with updated information and services, is located on the ..."
Abstract
-
Cited by 343 (0 self)
- Add to MetaCart
The online version of this article, along with updated information and services, is located on the
Distribution of multiple sclerosis
, 1998
"... Multiple sclerosis is primarily an infl ammatory disorder of the brain and spinal cord in which focal lymphocytic infi ltration leads to damage of myelin and axons. Initially, infl ammation is transient and remyelination occurs but is not durable. Hence, the early course of disease is characterised ..."
Abstract
-
Cited by 175 (3 self)
- Add to MetaCart
Multiple sclerosis is primarily an infl ammatory disorder of the brain and spinal cord in which focal lymphocytic infi ltration leads to damage of myelin and axons. Initially, infl ammation is transient and remyelination occurs but is not durable. Hence, the early course of disease is characterised
Diffusion Tensor Imaging Based Network Analysis Detects Alterations of Neuroconnectivity in Patients with Clinically Early Relapsing-Remitting Multiple Sclerosis
"... Abstract: Although it is inarguable that conventional MRI (cMRI) has greatly contributed to the diagnosis and assessment of multiple sclerosis (MS), cMRI does not show close correlation with clinical findings or pathologic features, and is unable to predict prognosis or stratify disease severity. To ..."
Abstract
-
Cited by 2 (0 self)
- Add to MetaCart
. To this end, diffusion tensor imaging (DTI) with tractography and neuroconnectivity analysis may assist disease assessment in MS. We, therefore, attempted this pilot study for initial assessment of early relapsing-remitting MS (RRMS). Neuroconnectivity analysis was used for evaluation of 24 early RRMS
Article Relation between Pro-inflammatory Cytokines and Acetylcholine Levels in Relapsing-Remitting Multiple Sclerosis Patients
, 2012
"... Abstract: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating and neurodegenerative disorder. Since acetylcholine (ACh) is known to participate in the inflammatory response, we investigated the possible relationship between pro-inflammatory cytokines and acetylcholine levels in relapsin ..."
Abstract
- Add to MetaCart
in relapsing-remitting multiple sclerosis (RR-MS) patients. Levels of ACh and pro-inflammatory cytokines IL1-β and IL-17 were measured both in cerebrospinal fluid (CSF) and sera of 22 RR-MS patients in the relapsing phase and in 17 control subjects affected by other non-neurological diseases (OND). We observed
Brain Activity Changes in Cognitive Networks in Relapsing-Remitting Multiple Sclerosis – Insights from a Longitudinal fMRI Study
"... Background: Extrapolations from previous cross-sectional fMRI studies suggest cerebral functional changes with progression of Multiple Sclerosis (MS), but longitudinal studies are scarce. We assessed brain activation changes over time in MS patients using a cognitive fMRI paradigm and examined corre ..."
Abstract
- Add to MetaCart
Background: Extrapolations from previous cross-sectional fMRI studies suggest cerebral functional changes with progression of Multiple Sclerosis (MS), but longitudinal studies are scarce. We assessed brain activation changes over time in MS patients using a cognitive fMRI paradigm and examined
Results 1 - 10
of
9,871
