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Integrated Droplet Routing in the Synthesis of Microfluidic Biochips*
"... Microfluidic biochips are revolutionizing many areas of biochemistry and biomedical sciences. Several synthesis tools have recently been proposed for the automated design of biochips from the specifications of laboratory protocols. However, only a few of these tools address the problem of droplet ro ..."
Abstract
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droplet pathways can be found for area-constrained biochip layouts; non-routable fabricated biochips must be discarded. We present a droplet-routing-aware automated synthesis tool for microfluidic biochips. Droplet routability, defined as the ease with which droplet pathways can be determined
Routing-Based Synthesis of Digital Microfluidic Biochips
"... Microfluidic biochips are replacing the conventional biochemical analyzers, and are able to integrate on-chip all the basic functions for biochemical analysis. The “digital ” microfluidic biochips are manipulating liquids not as a continuous flow, but as discrete droplets on a two-dimensional array ..."
Abstract
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Cited by 9 (6 self)
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Microfluidic biochips are replacing the conventional biochemical analyzers, and are able to integrate on-chip all the basic functions for biochemical analysis. The “digital ” microfluidic biochips are manipulating liquids not as a continuous flow, but as discrete droplets on a two-dimensional array
Cross-Contamination Avoidance for Droplet Routing in Digital Microfluidic Biochips
, 2009
"... Recent advances in droplet-based digital microfluidics have enabled biochip devices for DNA sequencing, immunoassays, clinical chemistry, and protein crystallization. Since crosscontamination between droplets of different biomolecules can lead to erroneous outcomes for bioassays, the avoidance of cr ..."
Abstract
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Cited by 10 (6 self)
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Recent advances in droplet-based digital microfluidics have enabled biochip devices for DNA sequencing, immunoassays, clinical chemistry, and protein crystallization. Since crosscontamination between droplets of different biomolecules can lead to erroneous outcomes for bioassays, the avoidance
Integrated Droplet Routing and Defect Tolerance in the Synthesis of Digital Microfluidic Biochips
, 2008
"... Microfluidic biochips are revolutionizing high-throughput DNA sequencing, immunoassays, and clinical diagnostics. As high-throughput bioassays are mapped to digital microfluidic platforms, the need for design automation techniques is being increasingly felt. Moreover, as most applications of biochip ..."
Abstract
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Cited by 8 (1 self)
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Microfluidic biochips are revolutionizing high-throughput DNA sequencing, immunoassays, and clinical diagnostics. As high-throughput bioassays are mapped to digital microfluidic platforms, the need for design automation techniques is being increasingly felt. Moreover, as most applications
Functional testing of digital microfluidic biochips
- Proc. ITC
, 2007
"... Dependability is an important attribute for microfluidic biochips that are used for safety-critical applications such as point-of-care health assessment, air-quality monitoring, and food-safety testing. Therefore, these devices must be adequately tested after manufacture and during bioassay operatio ..."
Abstract
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Cited by 16 (9 self)
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Dependability is an important attribute for microfluidic biochips that are used for safety-critical applications such as point-of-care health assessment, air-quality monitoring, and food-safety testing. Therefore, these devices must be adequately tested after manufacture and during bioassay
A contamination aware droplet routing algorithm for digital microfluidic biochips
- IEEE/ACM ICCAD
, 2009
"... Abstract—Recent advances of digital microfluidic biochips (DMFBs) have revolutionized the traditional laboratory proce-dures. By providing the droplet-based system, DMFB can per-form real-time biological analysis and safety-critical biomedical applications. However, different droplets being transpor ..."
Abstract
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Cited by 8 (4 self)
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Abstract—Recent advances of digital microfluidic biochips (DMFBs) have revolutionized the traditional laboratory proce-dures. By providing the droplet-based system, DMFB can per-form real-time biological analysis and safety-critical biomedical applications. However, different droplets being
Defect-Aware Synthesis of Droplet-Based Microfluidic Biochips*
"... Recent advances in microfluidics technology have led to the emergence of miniaturized biochip devices for biochemical analysis. A promising category of microfluidic biochips relies on the principle of electrowetting-on-dielectric, whereby discrete droplets of nanoliter volumes can be manipulated usi ..."
Abstract
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Cited by 3 (0 self)
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using an array of electrodes. As chemists adapt more bioassays for concurrent execution on such “digital ” droplet-based microfluidic platforms, system integration, design complexity, and the need for defect tolerance are expected to increase rapidly. Automated design tools for defect
Design Automation and Test Solutions for Digital Microfluidic Biochips
, 2010
"... Microfluidics-based biochips are revolutionizing high-throughput sequencing, parallel immunoassays, blood chemistry for clinical diagnostics, and drug discovery. These devices enable the precise control of nanoliter volumes of biochemical samples and reagents. They combine electronics with biology, ..."
Abstract
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Cited by 13 (2 self)
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, system integration, and less likelihood of human error. This tutorial paper provides an overview of droplet-based “digital” microfluidic biochips. It describes emerging computer-aided design (CAD) tools for the automated synthesis and optimization of biochips from bioassay protocols. Recent advances
A Novel Droplet Routing Algorithm for
, 2010
"... A novel droplet routing algorithm for digital microfluidic biochips ..."
Digital microfluidic biochips: recent research and emerging challenges
- In Proceedings of the Conference on Codesign and System Synthesis
"... Microfluidic biochips are replacing the conventional biochemical analyzers, and are able to integrate on-chip all the basic functions for biochemical analysis. The “digital ” microfluidic biochips (DM-FBs) are manipulating liquids not as a continuous flow, but as dis-crete droplets on a two-dimensio ..."
Abstract
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Cited by 2 (1 self)
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Microfluidic biochips are replacing the conventional biochemical analyzers, and are able to integrate on-chip all the basic functions for biochemical analysis. The “digital ” microfluidic biochips (DM-FBs) are manipulating liquids not as a continuous flow, but as dis-crete droplets on a two
Results 1 - 10
of
5,495
