Abstract. Active and passive measurements for topology discovery have known an impressive growth during the last decade. If a lot of work has been done regarding inter-domain topology discovery and modeling, only a few papers raise the question of how to extract intra-domain topologies from

Active and passive measurements for topology discovery have known an impressive growth during the last decade. While a lot of work has been done regarding inter-domain topology discovery and modeling, only a few papers raise the question of how to extract intra-domain topologies from measurements

To date, realistic ISP topologies have not been accessible to the research community, leaving work that depends on topology on an uncertain footing. In this paper, we present new Internet mapping techniques that have enabled us to directly measure router-level ISP topologies. Our techniques reduce

are usually formatted for use by people (e.g., the relevant content is embedded in HTML pages), so extracting their content is difficult. Wrappers are often used for this purpose. A wrapper is a procedure for extracting a particular resource's content. Unfortunately, hand-coding wrappers is tedious. We

Effective engineering of the Internet is predicated upon a detailed understanding of issues such as the large-scale structure of its underlying physical topology, the manner in which it evolves over time, and the way in which its constituent components contribute to its overall function

our observations of the microblogging phenomena by studying the topological and geographical properties of Twitter’s social network. We find that people use microblogging to talk about their daily activities and to seek or share information. Finally, we analyze the user intentions associated at a

Large-scale Internet applications can benefit from an ability to predict round-trip times to other hosts without having to contact them first. Explicit measurements are often unattractive because the cost of measurement can outweigh the benefits of exploiting proximity information. Vivaldi is a

a major routing pathology more than doubled between the end of 1994 and the end of 1995, rising from 1.5 % to 3.4%. For routing stability, we define two separate types of stability, “prevalence, ” meaning the overall likelihood that a particular route is encountered, and “persistence

ation, and termination phases of protein synthesis. Because the structures of several DNA and RNA polymerases have been determined at atomic resolution, the mechanisms of DNA and RNA synthesis are both well understood. Determination of the structure of the ribosome, however, has proven a daunting task. It is several times larger than the largest polymerase, and 100 times larger than lysozyme, the first enzyme to be understood at atomic resolution. Until now an atomic resolution structure for the ribosome has not been available, and as a result the mechanism of protein synthesis has remained a mystery. Electron microscopy has contributed to our understanding of ribosome structure ever since the ribosome was discovered. In the last few years, three-dimensional (3D) electron microscopic images of the ribosome have been produced at resolutions sufficiently high to visualize many of the proteins and nucleic acids that assist in protein synthesis bound to the ribosome (3). Earlier this yea

cultivation.of individual microbial cells without Phylogenetic identification and in situ detection