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254,907
Estimating the number of clusters in a dataset via the Gap statistic
, 2000
"... We propose a method (the \Gap statistic") for estimating the number of clusters (groups) in a set of data. The technique uses the output of any clustering algorithm (e.g. kmeans or hierarchical), comparing the change in within cluster dispersion to that expected under an appropriate reference ..."
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Cited by 492 (1 self)
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We propose a method (the \Gap statistic") for estimating the number of clusters (groups) in a set of data. The technique uses the output of any clustering algorithm (e.g. kmeans or hierarchical), comparing the change in within cluster dispersion to that expected under an appropriate reference
Gapped Blast and PsiBlast: a new generation of protein database search programs
 NUCLEIC ACIDS RESEARCH
, 1997
"... The BLAST programs are widely used tools for searching protein and DNA databases for sequence similarities. For protein comparisons, a variety of definitional, algorithmic and statistical refinements described here permits the execution time of the BLAST programs to be decreased substantially while ..."
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Cited by 8393 (85 self)
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for automatically combining statistically significant alignments produced by BLAST into a positionspecific score matrix, and searching the database using this matrix. The resulting PositionSpecific Iterated BLAST (PSIBLAST) program runs at approximately the same speed per iteration as gapped BLAST, but in many
A Systematic Comparison of Various Statistical Alignment Models
 COMPUTATIONAL LINGUISTICS
, 2003
"... ..."
Estimating Wealth Effects without Expenditure Data— or Tears
 Policy Research Working Paper 1980, The World
, 1998
"... Abstract: We use the National Family Health Survey (NFHS) data collected in Indian states in 1992 and 1993 to estimate the relationship between household wealth and the probability a child (aged 6 to 14) is enrolled in school. A methodological difficulty to overcome is that the NFHS, modeled closely ..."
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Cited by 832 (16 self)
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Abstract: We use the National Family Health Survey (NFHS) data collected in Indian states in 1992 and 1993 to estimate the relationship between household wealth and the probability a child (aged 6 to 14) is enrolled in school. A methodological difficulty to overcome is that the NFHS, modeled
Minimum Error Rate Training in Statistical Machine Translation
, 2003
"... Often, the training procedure for statistical machine translation models is based on maximum likelihood or related criteria. A general problem of this approach is that there is only a loose relation to the final translation quality on unseen text. In this paper, we analyze various training cri ..."
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Cited by 663 (7 self)
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Often, the training procedure for statistical machine translation models is based on maximum likelihood or related criteria. A general problem of this approach is that there is only a loose relation to the final translation quality on unseen text. In this paper, we analyze various training
Making the most of statistical analyses: Improving interpretation and presentation
 American Journal of Political Science
, 2000
"... Social scientists rarely take full advantage of the information available in their statistical results. As a consequence, they miss opportunities to present quantities that are of greatest substantive interest for their research and express the appropriate degree of certainty about these quantities. ..."
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Cited by 550 (24 self)
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Social scientists rarely take full advantage of the information available in their statistical results. As a consequence, they miss opportunities to present quantities that are of greatest substantive interest for their research and express the appropriate degree of certainty about these quantities
Estimating the Support of a HighDimensional Distribution
, 1999
"... Suppose you are given some dataset drawn from an underlying probability distribution P and you want to estimate a "simple" subset S of input space such that the probability that a test point drawn from P lies outside of S is bounded by some a priori specified between 0 and 1. We propo ..."
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Cited by 766 (29 self)
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Suppose you are given some dataset drawn from an underlying probability distribution P and you want to estimate a "simple" subset S of input space such that the probability that a test point drawn from P lies outside of S is bounded by some a priori specified between 0 and 1. We
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood
, 2003
"... The increase in the number of large data sets and the complexity of current probabilistic sequence evolution models necessitates fast and reliable phylogeny reconstruction methods. We describe a new approach, based on the maximumlikelihood principle, which clearly satisfies these requirements. The ..."
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Cited by 2109 (30 self)
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The increase in the number of large data sets and the complexity of current probabilistic sequence evolution models necessitates fast and reliable phylogeny reconstruction methods. We describe a new approach, based on the maximumlikelihood principle, which clearly satisfies these requirements. The core of this method is a simple hillclimbing algorithm that adjusts tree topology and branch lengths simultaneously. This algorithm starts from an initial tree built by a fast distancebased method and modifies this tree to improve its likelihood at each iteration. Due to this simultaneous adjustment of the topology and branch lengths, only a few iterations are sufficient to reach an optimum. We used extensive and realistic computer simulations to show that the topological accuracy of this new method is at least as high as that of the existing maximumlikelihood programs and much higher than the performance of distancebased and parsimony approaches. The reduction of computing time is dramatic in comparison with other maximumlikelihood packages, while the likelihood maximization ability tends to be higher. For example, only 12 min were required on a standard personal computer to analyze a data set consisting of 500 rbcL sequences with 1,428 base pairs from plant plastids, thus reaching a speed of the same order as some popular distancebased and parsimony algorithms. This new method is implemented in the PHYML program, which is freely available on our web page:
Results 1  10
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254,907