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122
Apixaban metabolism and pharmacokinetics after oral administration to humans. Drug Metab Dispos
, 2009
"... ABSTRACT: The metabolism and disposition of [ 14 C]apixaban, an orally bioavailable, highly selective, and direct acting/reversible factor Xa inhibitor, was investigated in 10 healthy male subjects without (group 1, n ؍ 6) and with bile collection (group 2, n ؍ 4) after a single 20-mg oral dose ..."
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Cited by 34 (3 self)
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as described above to give additional phenol product (0.117 g). Preparation of 4-(3-carbamoyl-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetra-hydropyrazolo[3,4-c]pyridin-1-yl)phenyl hydrogen sulfate (Odemethyl apixaban sulfate). To O-demethyl apixaban (0.48 g,1.07 mmol) in pyridine (2 ml) was added
Three-year trajectory of teachers’ fidelity to a drug prevention curriculum.
- Prevention Science,
, 2010
"... Abstract: Little is known about the trajectories over time of classroom teachers' fidelity to drug prevention curricula. Using the "Concerns-Based Adoption Model" (C-BAM) as a theoretical framework, we hypothesized that teachers' fidelity would improve with repetition. Participa ..."
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Cited by 1 (0 self)
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, or changed prescribed content, or delivered it using new methods. Study findings provided only partial support for the C-BAM model. Considerable variability in teachers' performance over time was noted, suggesting that their progression over time may be nonlinear and dynamic, and quite possibly a
A Novel Medium for the Enhanced Production of Cyclosporin A by Tolypocladium inflatum MTCC 557 Using Solid State Fermentation
, 2008
"... a promising drug owing to its immunosuppressive and antifungal activities. From an industrial point of view, the necessity to obtain a suitable and economic medium for higher production of CyA was the aim of this work. The present study evaluated the effect of different fermentation parameters in so ..."
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was carried out at 25±2 o C for 9 days. A combination of hydrolyzed wheat bran flour and coconut oil cake (1:1) at 70 % initial moisture content supported a maximum production of 3,872±156 mg CyA/kg substrate as compared with 792±33 mg/kg substrate before optimization. Furthermore, supplementation of salts
BDRS PRICE DESCRIPTOR,
"... This report focuses on the evidence about the health.consequences of smoking for women, and is intended to serve.the public health and medical communities as 'a unified source of existing scientific research. The major issues about tobacco use and women's health are examined, including tre ..."
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trends in consumption, biomedical evidence, and determinants of smoking ititiation, maintenance, and cessation. The biomedical aspects ofsmoking are presented in terms of mortality, morbiplity, cardiovasculaidiseases, cancer, pregnancy and infant,health,, Teptic ulcer disease, drug reactions and
Comparing simple and advanced video tools as supports for complex collaborative design processes.
- Journal of the Learning Sciences.
, 2010
"... Full terms and conditions of use: http://www.informaworld.com/terms-and-conditions-of-access.pdf This article may be used for research, teaching and private study purposes. Any substantial or systematic reproduction, re-distribution, re-selling, loan or sub-licensing, systematic supply or distribut ..."
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Cited by 5 (0 self)
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playback tool with a word processor to perform the same design task. Results indicated that the advanced video editing tool was more effective in relation to (a) fostering student understanding of the topic and acquisition of cognitive skills, (b) the quality of student design products, and (c
Absorption, disposition, and metabolism of trans-methyl styryl ketone in female B6C3F1 mice. Drug Metab Dispos 25:1184–1190.
, 1997
"... ABSTRACT: trans-Methyl styryl ketone (MSK; trans-4-phenyl-3-buten-2-one) is a -unsaturated ketone that has a wide range of uses in industry, as well as consumer products. MSK does not appear to be overtly toxic in animal models, however, it has been shown to be mutagenic in several in vitro assays ..."
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Cited by 5 (0 self)
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iv, oral, and dermal exposure in the female B6C3F 1 mouse. Materials and Methods Chemicals. Universally ring labeled [ 14 C]MSK (trans-4-phenyl-3-buten-2-one) was obtained from Chemsyn Science Laboratories (Lenexa, KS) and was greater than 98% pure as determined by both normal and reversed phase HPLC
AGR 05
"... Responses of soil biological processes to elevated atmospheric [CO2] and nitrogen addition in a poplar plantation ..."
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Responses of soil biological processes to elevated atmospheric [CO2] and nitrogen addition in a poplar plantation
Contents lists availab
, 2013
"... Controls on the decomposition rate of soil organic carbon (SOC), especially the more stable fraction of Schmidt et al., 2011). While the age of most soil organic C (SOC), including that found in the top 20 cm of the mineral soil, extends into centuries (Trumbore et al., 1996; Fissore et al., 2009), ..."
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), the very large size of this reservoir means that even small increases in the a large influence on atmospheric [CO2]. Global temperatures are n is strongly tem-transfer of C from se in atmospheric ng (Holland et al., temperature re-e, the realized e as of SOC decompo-ted future rates of SOC decomposition
Results 1 - 10
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122
