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The Time-Rescaling Theorem and Its Application to Neural Spike Train Data Analysis

by Emery N. Brown, Riccardo Barbieri, Valerie Ventura, Robert E. Kass, Loren M. Frank - NEURAL COMPUTATION , 2001
"... Measuring agreement between a statistical model and a spike train data series, that is, evaluating goodness of fit, is crucial for establishing the model’s validity prior to using it to make inferences about a particular neural system. Assessing goodness-of-fit is a challenging problem for point pro ..."
Abstract - Cited by 131 (23 self) - Add to MetaCart
, inhomogeneous Poisson, and inhomogeneous Markov interval models of neural spike trains from the sup-

NOTE Communicated by Jonathan Victor The Time-Rescaling Theorem and Its Application to Neural Spike Train

by Data Analysis, Emery N. Brown, Riccardo Barbieri, Robert E. Kass, Loren M. Frank
"... Measuring agreement between a statistical model and a spike train data series, that is, evaluating goodness of �t, is crucial for establishing the model’s validity prior to using it to make inferences about a particular neural system. Assessing goodness-of-�t is a challenging problem for point proce ..."
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, inhomogeneous Poisson, and inhomogeneou s Markov interval models of neural spike trains from the sup-Neural Computation 14, 325–346 (2001)

Estimating statistics of neuronal dynamics via Markov chains

by Gary Froyland, Kazuyuki Aihara , 2000
"... We present an ecient computational method for estimating the mean and variance of interspike intervals dened by the timing of spikes in typical orbits of one-dimensional neuronal maps. This is equivalent to nding the mean and variance of return times of orbits to particular regions of phase spac ..."
Abstract - Cited by 2 (0 self) - Add to MetaCart
space. Rather than computing estimates directly from time series, the system is modelled as a nite state Markov chain to extract stationary behaviour in the form of invariant measures and average absorption times. Ergodic-theoretic formulae are then applied to produce the estimates without the need

Spike-frequency adapting neural ensembles: Beyond mean adaptation and renewal theories

by Eilif Muller, Lars Buesing, Johannes Schemmel, Karlheinz Meier - Neural Computation , 2007
"... We propose a Markov process model for spike-frequency adapting neural en-sembles which synthesizes existing mean-adaptation approaches, population density methods, and inhomogeneous renewal theory, resulting in a unied and tractable framework which goes beyond renewal and mean-adaptation theories by ..."
Abstract - Cited by 18 (1 self) - Add to MetaCart
We propose a Markov process model for spike-frequency adapting neural en-sembles which synthesizes existing mean-adaptation approaches, population density methods, and inhomogeneous renewal theory, resulting in a unied and tractable framework which goes beyond renewal and mean-adaptation theories

Efficient spike-sorting of multi-state neurons using inter-spike non-parametric method for automatic neural spikes clustering 23 hal-00639412, version 1 - 9 Nov 2011 intervals information. Journal of neuroscience methods

by Matthieu Delescluse, Christophe Pouzat , 2006
"... We demonstrate the efficacy of a new spike-sorting method based on a Markov Chain Monte Carlo (MCMC) algorithm by applying it to real data recorded from Purkinje cells (PCs) in young rat cerebellar slices. This algorithm is unique in its capability to estimate and make use of the firing statistics a ..."
Abstract - Cited by 15 (0 self) - Add to MetaCart
We demonstrate the efficacy of a new spike-sorting method based on a Markov Chain Monte Carlo (MCMC) algorithm by applying it to real data recorded from Purkinje cells (PCs) in young rat cerebellar slices. This algorithm is unique in its capability to estimate and make use of the firing statistics

LETTER Communicated by Adrienne Fairhall Spike Train Probability Models for Stimulus-Driven Leaky Integrate-and-Fire Neurons

by Shinsuke Koyama, Robert E. Kass
"... Mathematical models of neurons are widely used to improve understanding of neuronal spiking behavior. These models can produce artificial spike trains that resemble actual spike train data in important ways, but they are not very easy to apply to the analysis of spike train data. Instead, statistica ..."
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, statistical methods based on point process models of spike trains provide a wide range of data-analytical techniques. Two simplified point process models have been introduced in the literature: the time-rescaled renewal process (TRRP) and the multiplicative inhomogeneous Markov interval (m-IMI) model

Journal of Neuroscience Methods 105 (2001) 25–37 Construction and analysis of non-Poisson stimulus-response models of neural spiking activity

by Riccardo Barbieri A, Michael C. Quirk B, Loren M. Frank B, Matthew A. Wilson B, Emery N. Brown A
"... A paradigm for constructing and analyzing non-Poisson stimulus-response models of neural spike train activity is presented. Inhomogeneous gamma (IG) and inverse Gaussian (IIG) probability models are constructed by generalizing the derivation of the inhomogeneous Poisson (IP) model from the exponenti ..."
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A paradigm for constructing and analyzing non-Poisson stimulus-response models of neural spike train activity is presented. Inhomogeneous gamma (IG) and inverse Gaussian (IIG) probability models are constructed by generalizing the derivation of the inhomogeneous Poisson (IP) model from

A new look at state-space models for neural data

by Liam Paninski, Yashar Ahmadian, Daniel Gil Ferreira, Shinsuke Koyama, Kamiar Rahnama Rad, Michael Vidne, Joshua Vogelstein, Wei Wu - Journal of Computational Neuroscience , 2010
"... State space methods have proven indispensable in neural data analysis. However, common methods for performing inference in state-space models with non-Gaussian observations rely on certain approximations which are not always accurate. Here we review direct optimization methods that avoid these appro ..."
Abstract - Cited by 53 (25 self) - Add to MetaCart
these approximations, but that nonetheless retain the computational efficiency of the approximate methods. We discuss a variety of examples, applying these direct optimization techniques to problems in spike train smoothing, stimulus decoding, parameter estimation, and inference of synaptic properties. Along the way

Slice Normalized Dynamic Markov Logic Networks

by Tivadar Papai, Henry Kautz, Daniel Stefankovic
"... Markov logic is a widely used tool in statistical relational learning, which uses a weighted first-order logic knowledge base to specify a Markov random field (MRF) or a conditional random field (CRF). In many applications, a Markov logic network (MLN) is trained in one domain, but used in a differe ..."
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model, slice normalized dynamic Markov logic networks (SN-DMLN), that suffers from none of these issues. It supports efficient online inference, and can directly model influences between variables within a time slice that do not have a causal direction, in contrast with fully directed models (e.g., DBNs

Sampling Properties of the Spectrum and Coherency of Sequences of Action Potentials

by M. R. Jarvis, P. P. Mitra - Neural Computation
"... The spectrum and coherency are useful quantities for characterizing the temporal correlations and functional relations within and between point processes. This paper begins with a review of these quantities, their interpretation and how they may be estimated. A discussion of how to assess the statis ..."
Abstract - Cited by 54 (4 self) - Add to MetaCart
on a doubly stochastic inhomogeneous Poisson process model in which the rate functions are drawn from a low variance Gaussian process. It is found that, in contrast to continuous processes, the variance of the estimators cannot be reduced by smoothing beyond a scale which is set by the number of point
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