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Change Management and Synchronization of Local and Shared Versions of Controlled Vocabulary
, 2000
"... To share clinical data and to build interoperating computer systems that permit data entry, data retrieval, and data analysis, users and systems at multiple sites must share a common controlled clinical vocabulary (or ontology). However, local sites that adopt a shared vocabulary have local needs, a ..."
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Cited by 7 (0 self)
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and local versions of a browser and an editor and in a synchronization-support tool. I evaluated my model and methods by performing the synchronization process on a small test set of medical concepts in the subdomain of rickettsial diseases. I obtained content from medical textbooks published at different
30 Extended Abstract: Analysis of Medical Treatments Using Data Mining Techniques Analysis of Medical Treatments Using Data Mining Techniques
"... Abstract—Since in health care systems the amount of data is continuously growing, data mining techniques can be applied to analyse these large collections and gain interesting insights. However, some critical issues should be properly addressed. For example, data collections on patient treatments ar ..."
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classification algorithm. The clustering approach is named multiple-level because we apply the clustering algorithm in a multiple-level fashion, by focusing on different dataset portions and locally identifying groups of patients with similar profile and examination history. The classification algorithm is used
RESEARCH Open Access VarRanker: rapid prioritization of sequence variations associated with human disease
"... Background: Identification of the genetic alterations responsible for human disease is a central challenge facing medical genetics. While many algorithms have been developed to predict the degree of damage caused by a given sequence alteration, few tools are able to incorporate information about a g ..."
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Background: Identification of the genetic alterations responsible for human disease is a central challenge facing medical genetics. While many algorithms have been developed to predict the degree of damage caused by a given sequence alteration, few tools are able to incorporate information about a
Automatic screening of polycystic kidney disease in x-ray CT images of laboratory mice
"... This paper describes the application of a statistical-based deformable model algorithm to the segmentation of kidneys in x-ray computed tomography (CT) images of laboratory mice. This segmentation algorithm has been developed as the crucial first step in a process to automatically screen mice for ge ..."
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This paper describes the application of a statistical-based deformable model algorithm to the segmentation of kidneys in x-ray computed tomography (CT) images of laboratory mice. This segmentation algorithm has been developed as the crucial first step in a process to automatically screen mice
The bi-elliptical deformable contour and its application to automated tongue segmentation in chinese medicine
- IEEE Transactions on Medical Imaging
, 2005
"... Abstract—Automated tongue image segmentation, in Chinese medicine, is difficult due to two special factors: 1) there are many pathological details on the surface of the tongue, which have a large influence on edge extraction; 2) the shapes of the tongue bodies captured from various persons (with dif ..."
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Cited by 7 (2 self)
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different diseases) are quite different, so they are impossible to describe properly using a predefined deformable template. To address these problems, in this paper, we propose an original technique that is based on a combination of a bi-elliptical deformable template (BEDT) and an active contour model
Capturing phenotypes for precision medicine | COMMENTARY Molecular Case Studies
"... Abstract Deep phenotyping followed by integrated computational analysis of genotype and phenotype is becoming ever more important for many areas of genomic diagnostics and translational research. The overwhelming majority of clinical descriptions in the medical literature are available only as natu ..."
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are observed and described, generally in such a way as to be computationally accessible. Precision medicine has the goal of providing the best available care for each patient based on stratification into disease subclasses for which there is a common biological basis. The comprehensive discovery
EVALUATION OF NOVEL BIOMARKERS FOR CORONARY ARTERY DISEASE AMONG SYMPTOMATIC PATIENTS: STATISTICAL METHODOLOGY AND APPLICATION EVALUATION OF NOVEL BIOMARKERS FOR CORONARY ARTERY DISEASE AMONG SYMPTOMATIC PATIENTS: STATISTICAL METHODOLOGY AND APPLICATION
, 2011
"... ABSTRACT Proteomics has led to the discovery of several biomarkers within an individual's bloodstream that can be used in the diagnostic process for disease. Identification of novel biomarkers have a significant impact in the area of public health, with the potential to replace existing diagno ..."
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AND APPLICATION Daniel Lans, M.S. University of Pittsburgh, 2013 v patients that did not have clinically relevant coronary disease based on currently used clinical risk factors increased greatly, from zero to approximately thirty percent of the patients, with the inclusion of the biomarker panel. The use of a
MiTAP for Bio-Security: A Case Study Global Tracking of Infectious Disease Outbreaks and Emerging Biological Threats
"... Abstract * MiTAP (MITRE Text and Audio Processing) is a prototype system available for monitoring infectious disease outbreaks and other global events. MiTAP focuses on providing timely, multi-lingual, global information access to medical experts and individuals involved in humanitarian assistance ..."
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Abstract * MiTAP (MITRE Text and Audio Processing) is a prototype system available for monitoring infectious disease outbreaks and other global events. MiTAP focuses on providing timely, multi-lingual, global information access to medical experts and individuals involved in humanitarian assistance
Reviewer
"... Abstract. Under the umbrella of the Semantic Web, Linking Open Data projects have made available a large number of seman-tically intra- and inter-connected links. As an example, in the biomedical domain, data about disorders, disease related genes and proteins, clinical trials, and drugs or interven ..."
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or interventions are accessible on the Linked Open Data cloud. In addition, domain ontologies have been used to annotate scientific data. For instance, publications in PubMed have been annotated using controlled vocabulary (CV) terms from ontologies such as the Medical Subject Header (MeSH) or the Unified Medical
Automated Heart Wall Motion Abnormality Detection From Ultrasound Images using Bayesian Networks
"... Coronary Heart Disease can be diagnosed by measuring and scoring regional motion of the heart wall in ultrasound images of the left ventricle (LV) of the heart. We describe a completely automated and robust technique that detects diseased hearts based on detection and automatic tracking of the endoc ..."
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Coronary Heart Disease can be diagnosed by measuring and scoring regional motion of the heart wall in ultrasound images of the left ventricle (LV) of the heart. We describe a completely automated and robust technique that detects diseased hearts based on detection and automatic tracking
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