The IBM Blue Gene project has endeavored to develop a cellular architecture computer with millions of concurrent threads of execution. One of the major challenges of this project is demonstrating that applications can successfully exploit this massive amount of parallelism. Starting from

Abstract: NAMD is a parallel molecular dynamics code designed for high-performance simulation of large biomolecular systems. NAMD scales to hundreds of processors on high-end parallel platforms, as well as tens of processors on low-cost commodity clusters, and also runs on individual desktop

Abstract "Grid" computing has emerged as an important new field, distinguished from conventional distributed computing by its focus on large-scale resource sharing, innovative applications, and, in some cases, high-performance orientation. In this article, we define this new field. First

demonstrate a few applications of having high dynamic range radiance maps, such as synthesizing realistic motion blur and simulating the response of the human visual system.

We present algorithms for coupling and training hidden Markov models (HMMs) to model interacting processes, and demonstrate their superiority to conventional HMMs in a vision task classifying two-handed actions. HMMs are perhaps the most successful framework in perceptual computing for modeling

This paper presents the design and implementation of the Intentional Naming System (INS), a resource discovery and service location system for dynamic and mobile networks of devices and computers. Such environments require a naming system that is (i) expressive, to describe and make requests based

are challenging problems due to the considerable diversity, large numbers, dynamic behavior, and geographical distribution of the entities in which a user might be interested. Consequently, information services are a vital part of any Grid software infrastructure, providing fundamental mechanisms for discovery

of computational experience for a variety of applications. Part I1 of this study (to appear in a subsequent issue) examines more advanced considerations, applying the basic ideas to special settings and outlining a dynamic move structure to insure finiteness. Part I1 also describes tabu search methods for solving

Molecular dynamics programs simulate the behavior of biomolecular systems, leading to insights and understanding of their functions. However, the computational complexity of such simulations is enormous. Parallel machines provide the potential to meet this computational challenge. To harness

and decompositions and facilitates the prototyping of a million node Processing-In-Memory array to achieve petaflop performance during a molecular dynamics simulation typical of protein folding. In addition, simulations are used to validate the model and parallel implementations are demonstrated. Although parallel