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23,954
Convex Analysis
, 1970
"... In this book we aim to present, in a unified framework, a broad spectrum of mathematical theory that has grown in connection with the study of problems of optimization, equilibrium, control, and stability of linear and nonlinear systems. The title Variational Analysis reflects this breadth. For a lo ..."
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Cited by 5350 (67 self)
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In this book we aim to present, in a unified framework, a broad spectrum of mathematical theory that has grown in connection with the study of problems of optimization, equilibrium, control, and stability of linear and nonlinear systems. The title Variational Analysis reflects this breadth. For a long time, ‘variational ’ problems have been identified mostly with the ‘calculus of variations’. In that venerable subject, built around the minimization of integral functionals, constraints were relatively simple and much of the focus was on infinitedimensional function spaces. A major theme was the exploration of variations around a point, within the bounds imposed by the constraints, in order to help characterize solutions and portray them in terms of ‘variational principles’. Notions of perturbation, approximation and even generalized differentiability were extensively investigated. Variational theory progressed also to the study of socalled stationary points, critical points, and other indications of singularity that a point might have relative to its neighbors, especially in association with existence theorems for differential equations.
A Compositional Approach to Performance Modelling
, 1996
"... Performance modelling is concerned with the capture and analysis of the dynamic behaviour of computer and communication systems. The size and complexity of many modern systems result in large, complex models. A compositional approach decomposes the system into subsystems that are smaller and more ea ..."
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Cited by 746 (102 self)
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Performance modelling is concerned with the capture and analysis of the dynamic behaviour of computer and communication systems. The size and complexity of many modern systems result in large, complex models. A compositional approach decomposes the system into subsystems that are smaller and more
Graphical models, exponential families, and variational inference
, 2008
"... The formalism of probabilistic graphical models provides a unifying framework for capturing complex dependencies among random variables, and building largescale multivariate statistical models. Graphical models have become a focus of research in many statistical, computational and mathematical fiel ..."
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Cited by 800 (26 self)
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The formalism of probabilistic graphical models provides a unifying framework for capturing complex dependencies among random variables, and building largescale multivariate statistical models. Graphical models have become a focus of research in many statistical, computational and mathematical fields, including bioinformatics, communication theory, statistical physics, combinatorial optimization, signal and image processing, information retrieval and statistical machine learning. Many problems that arise in specific instances — including the key problems of computing marginals and modes of probability distributions — are best studied in the general setting. Working with exponential family representations, and exploiting the conjugate duality between the cumulant function and the entropy for exponential families, we develop general variational representations of the problems of computing likelihoods, marginal probabilities and most probable configurations. We describe how a wide varietyof algorithms — among them sumproduct, cluster variational methods, expectationpropagation, mean field methods, maxproduct and linear programming relaxation, as well as conic programming relaxations — can all be understood in terms of exact or approximate forms of these variational representations. The variational approach provides a complementary alternative to Markov chain Monte Carlo as a general source of approximation methods for inference in largescale statistical models.
An introduction to variational methods for graphical models
 TO APPEAR: M. I. JORDAN, (ED.), LEARNING IN GRAPHICAL MODELS
"... ..."
Optimization Flow Control, I: Basic Algorithm and Convergence
 IEEE/ACM TRANSACTIONS ON NETWORKING
, 1999
"... We propose an optimization approach to flow control where the objective is to maximize the aggregate source utility over their transmission rates. We view network links and sources as processors of a distributed computation system to solve the dual problem using gradient projection algorithm. In thi ..."
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Cited by 690 (64 self)
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We propose an optimization approach to flow control where the objective is to maximize the aggregate source utility over their transmission rates. We view network links and sources as processors of a distributed computation system to solve the dual problem using gradient projection algorithm. In this system sources select transmission rates that maximize their own benefits, utility minus bandwidth cost, and network links adjust bandwidth prices to coordinate the sources' decisions. We allow feedback delays to be different, substantial and timevarying, and links and sources to update at different times and with different frequencies. We provide asynchronous distributed algorithms and prove their convergence in a static environment. We present measurements obtained from a preliminary prototype to illustrate the convergence of the algorithm in a slowly timevarying environment.
Planning Algorithms
, 2004
"... This book presents a unified treatment of many different kinds of planning algorithms. The subject lies at the crossroads between robotics, control theory, artificial intelligence, algorithms, and computer graphics. The particular subjects covered include motion planning, discrete planning, planning ..."
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Cited by 1108 (51 self)
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This book presents a unified treatment of many different kinds of planning algorithms. The subject lies at the crossroads between robotics, control theory, artificial intelligence, algorithms, and computer graphics. The particular subjects covered include motion planning, discrete planning, planning under uncertainty, sensorbased planning, visibility, decisiontheoretic planning, game theory, information spaces, reinforcement learning, nonlinear systems, trajectory planning, nonholonomic planning, and kinodynamic planning.
Modeling and simulation of genetic regulatory systems: A literature review
 JOURNAL OF COMPUTATIONAL BIOLOGY
, 2002
"... In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between ..."
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Cited by 729 (15 self)
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In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The regulation of gene expression is achieved through genetic regulatory systems structured by networks of interactions between DNA, RNA, proteins, and small molecules. As most genetic regulatory networks of interest involve many components connected through interlocking positive and negative feedback loops, an intuitive understanding of their dynamics is hard to obtain. As a consequence, formal methods and computer tools for the modeling and simulation of genetic regulatory networks will be indispensable. This paper reviews formalisms that have been employed in mathematical biology and bioinformatics to describe genetic regulatory systems, in particular directed graphs, Bayesian networks, Boolean networks and their generalizations, ordinary and partial differential equations, qualitative differential equations, stochastic equations, and rulebased formalisms. In addition, the paper discusses how these formalisms have been used in the simulation of the behavior of actual regulatory systems.
A theory of timed automata
, 1999
"... Model checking is emerging as a practical tool for automated debugging of complex reactive systems such as embedded controllers and network protocols (see [23] for a survey). Traditional techniques for model checking do not admit an explicit modeling of time, and are thus, unsuitable for analysis of ..."
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Cited by 2651 (32 self)
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Model checking is emerging as a practical tool for automated debugging of complex reactive systems such as embedded controllers and network protocols (see [23] for a survey). Traditional techniques for model checking do not admit an explicit modeling of time, and are thus, unsuitable for analysis of realtime systems whose correctness depends on relative magnitudes of different delays. Consequently, timed automata [7] were introduced as a formal notation to model the behavior of realtime systems. Its definition provides a simple way to annotate statetransition graphs with timing constraints using finitely many realvalued clock variables. Automated analysis of timed automata relies on the construction of a finite quotient of the infinite space of clock valuations. Over the years, the formalism has been extensively studied leading to many results establishing connections to circuits and logic, and much progress has been made in developing verification algorithms, heuristics, and tools. This paper provides a survey of the theory of timed automata, and their role in specification and verification of realtime systems.
Statecharts: A Visual Formalism For Complex Systems
, 1987
"... We present a broad extension of the conventional formalism of state machines and state diagrams, that is relevant to the specification and design of complex discreteevent systems, such as multicomputer realtime systems, communication protocols and digital control units. Our diagrams, which we cal ..."
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Cited by 2683 (56 self)
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We present a broad extension of the conventional formalism of state machines and state diagrams, that is relevant to the specification and design of complex discreteevent systems, such as multicomputer realtime systems, communication protocols and digital control units. Our diagrams, which we call statecharts, extend conventional statetransition diagrams with essentially three olements, dealing, respectively, with the notions of hierarchy, concurrency and communication. These transform the language of state diagrams into a highly structured' and economical description language. Statecharts are thus compact and expressivesmall diagrams can express complex behavioras well as compositional and modular. When coupled with the capabilities of computerized graphics, statecharts enable viewing the description at different levels of detail, and make even very large specifications manageable and comprehensible. In fact, we intend to demonstrate here that statecharts counter many of the objections raised against conventional state diagrams, and thus appear to render specification by diagrams an attractive and plausible approach. Statecharts can be used either as a standalone behavioral description or as part of a more general design methodology that deals also with the system's other aspects, such as functional decomposition and dataflow specification. We also discuss some practical experience that was gained over the last three years in applying the statechart formalism to the specification of a particularly complex system.
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