Pfam is a comprehensive collection of protein domains and families, represented as multiple sequence alignments and as profile hidden Markov models. The current release of Pfam (22.0) contains 9318 protein families. Pfam is now based not only on the UniProtKB sequence database, but also on NCBI Gen

this article, we discuss the fundamentals of distributed DBMS technology. We address the data distribution and architectural design issues as well as the algorithms that need to be implemented to provide the basic DBMS functions such as query processing, concurrency control, reliability, and replication control.

We present a novel language for querying object-oriented databases. The language is built around the idea of extended path expressions that substantially generalize [ZAN83], and on an adaptation of the first-order formalization of object-oriented languages from [KW89, KLW90, KW92]. The language

Abstract: Parallel database machine architectures have evolved from the use of exotic hardware to a software parallel dataflow architecture based on conventional shared-nothing hardware. These new designs provide impressive speedup and scaleup when processing relational database queries. This paper

We propose an indexing method for time sequences for processing similarity queries. We use the Discrete Fourier Transform (DFT) to map time sequences to the frequency domain, the crucial observation being that, for most sequences of practical interest, only the first few frequencies are strong. Another important observation is Parseval's theorem, which specifies that the Fourier transform preserves the Euclidean distance in the time or frequency domain. Having thus mapped sequences to a lower-dimensionality space by using only the first few Fourier coe cients, we use R-trees to index the sequences and e ciently answer similarity queries. We provide experimental results which show that our method is superior to search based on sequential scanning. Our experiments show that a few coefficients (1-3) are adequate to provide good performance. The performance gain of our method increases with the number and length of sequences.

this article. 0738-4602/92/$4.00 1992 AAAI 58 AI MAGAZINE for the 1990s (Silberschatz, Stonebraker, and Ullman 1990)

Workflow management promises a new solution to an age-old problem: controlling, monitoring, optimizing and supporting business processes. What is new about workflow management is the explicit representation of the business process logic which allows for computerized support. This paper discusses

will play in knowledge management and in electronic commerce. In addition, I show how arising web standards such as RDF and XML can be used as

Interact hosting centers serve multiple service sites from a common hardware base. This paper presents the design and implementation of an architecture for resource management in a hosting center op-erating system, with an emphasis on energy as a driving resource management issue for large server

, and execution. We evaluate these issues in the context of TinyDB, a distributed query processor for smart sensor devices, and show how acquisitional techniques can provide significant reductions in power consumption on our sensor devices. Categories and Subject Descriptors: H.2.3 [Database Management