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Clustering techniques for protein surfaces

by L. Baldacci, M. Golfarelli, A. Lumini, S. Rizzi , 2006
"... www.elsevier.com/locate/patcog Though most approaches to protein comparison are based on their structure, several studies produced evidence of a strict correlation between the surface characteristics of proteins and the way they interact. Surface-based techniques for protein comparison typically req ..."
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www.elsevier.com/locate/patcog Though most approaches to protein comparison are based on their structure, several studies produced evidence of a strict correlation between the surface characteristics of proteins and the way they interact. Surface-based techniques for protein comparison typically

Crystal structure of rhodopsin: a G protein-coupled receptor

by Krzysztof Palczewski, Takashi Kumasaka, Tetsuya Hori, Craig A. Behnke, Hiroyuki Motoshima, Brian A. Fox, Isolde Le Trong, David C. Teller, Tetsuji Okada, Ronald E. Stenkamp, Masaki Yamamoto, Masashi Miyano - LeTrong I, Teller DC, Okada T, Stenkamp RE et , 2000
"... Heterotrimeric guanine nucleotideÐbinding protein (G protein)Ðcoupled recep-tors (GPCRs) respond to a variety of different external stimuli and activate G proteins. GPCRs share many structural features, including a bundle of seven transmembrane a helices connected by six loops of varying lengths. We ..."
Abstract - Cited by 376 (4 self) - Add to MetaCart
-state chromophore, 11-cis-ret-inal, holds the transmembrane region of the protein in the inactive confor-mation. Interactions of the chromophore with a cluster of key residues deter-mine the wavelength of the maximum absorption. Changes in these interactions among rhodopsins facilitate color discrimination

Clustered intrinsic connections in cat visual cortex

by Charles D. Gilbert, Torsten, N. Wiesel - J. Neurosci , 1983
"... The intrinsic connections of the cortex have long been known to run vertically, across the cortical layers. In the present study we have found that individual neurons in the cat primary visual cortex can communicate over suprisingly long distances horizontally (up to 4 mm), in directions parallel to ..."
Abstract - Cited by 131 (5 self) - Add to MetaCart
to the cortical surface. For all of the cells having widespread projections, the collaterals within their axonal fields were distributed in repeating clusters, with an average periodicity of 1 mm. This pattern of extensive clustered projections has been revealed by combining the techniques of intracellular

Reverse engineering of regulatory networks in human B cells.

by Katia Basso , Adam A Margolin , Gustavo Stolovitzky , Ulf Klein , Riccardo Dalla-Favera , Andrea Califano - Nat. Genet. , 2005
"... Cellular phenotypes are determined by the differential activity of networks linking coregulated genes. Available methods for the reverse engineering of such networks from genome-wide expression profiles have been successful only in the analysis of lower eukaryotes with simple genomes. Using a new m ..."
Abstract - Cited by 178 (2 self) - Add to MetaCart
of both protein-protein interaction and metabolic networks is of a hierarchical scale-free nature 1,2 , characterized by an inverse relationship between the number of nodes and their connectivity (scale-free) and by a preferential interaction among highly connected genes, called hubs (hierarchical

A Template-Matching Approach for Protein Surface Clustering

by unknown authors
"... Surface-based techniques for protein comparison and classification typically require a compact surface representation, capable of effectively condensing its description. In this paper we propose an original template-matching algorithm for multi-feature surface clustering in the biochemical context. ..."
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Surface-based techniques for protein comparison and classification typically require a compact surface representation, capable of effectively condensing its description. In this paper we propose an original template-matching algorithm for multi-feature surface clustering in the biochemical context

A Template-Matching Approach for Protein Surface Clustering

by L. Baldacci, M. Golfarelli, A. Lumini, S. Rizzi
"... Surface-based techniques for protein comparison and classification typically require a compact surface representation, capable of effectively condensing its description. In this paper we propose an original template-matching algorithm for multi-feature surface clustering in the biochemical context. ..."
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Surface-based techniques for protein comparison and classification typically require a compact surface representation, capable of effectively condensing its description. In this paper we propose an original template-matching algorithm for multi-feature surface clustering in the biochemical context

Cluster-Preserving Embedding of Proteins

by By Gabriela Hristescu, Martin Farach-colton , 1999
"... Similarity searching in protein sequence databases is a standard technique for biologists dealing with a newly sequenced protein. Exhaustive search in such databases is prohibitive because of the large sizes of these database and because pairwise comparisons are slow. Heuristic techniques, such as F ..."
Abstract - Cited by 58 (0 self) - Add to MetaCart
Similarity searching in protein sequence databases is a standard technique for biologists dealing with a newly sequenced protein. Exhaustive search in such databases is prohibitive because of the large sizes of these database and because pairwise comparisons are slow. Heuristic techniques

A unified hierarchical algorithm for global illumination with scattering volumes and object clusters

by François X. Sillion - IEEE Trans. Vis. Comput. Graph , 1995
"... Abstract — This paper presents a new radiosity algorithm that allows the simultaneous computation of energy exchanges between surface elements, scattering volume distributions, and groups of surfaces, or object clusters. The new technique is based on a hierarchical formulation of the zonal method, a ..."
Abstract - Cited by 114 (26 self) - Add to MetaCart
Abstract — This paper presents a new radiosity algorithm that allows the simultaneous computation of energy exchanges between surface elements, scattering volume distributions, and groups of surfaces, or object clusters. The new technique is based on a hierarchical formulation of the zonal method

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellulax matrix: a role in cytoskeletal assembly

by Keith Burridge, Christopher E. Turner, Lewis H. Romerw - J. Cell , 1992
"... Abstract. Cells in culture reveal high levels of protein tyrosine phosphorylation in their focal adhesions, the regions where cells adhere to the underlying substratum. We have examined the tyrosine phosphorylation of proteins in response to plating cells on extracellular matrix substrata. Rat embry ..."
Abstract - Cited by 152 (11 self) - Add to MetaCart
embryo fibroblasts, mouse Balb/c 3T3, and NIH 3T3 cells plated on fibronectin-coated surfaces revealed elevated phosphotyrosine levels in a cluster of proteins between 115 and 130 kD. This increase in tyrosine phosphorylation was also seen when rat embryo fibroblasts were plated on laminin or vitronectin

iLamps: Geometrically aware and self-configuring projectors

by Ramesh Raskar, Jeroen van Baar, Paul Beardsley, Thomas Willwacher, Srinivas Rao, Clifton Forlines - ACM TOG , 2003
"... Projectors are currently undergoing a transformation as they evolve from static output devices to portable, environment-aware, communicating systems. An enhanced projector can determine and respond to the geometry of the display surface, and can be used in an ad-hoc cluster to create a self-configur ..."
Abstract - Cited by 137 (14 self) - Add to MetaCart
Projectors are currently undergoing a transformation as they evolve from static output devices to portable, environment-aware, communicating systems. An enhanced projector can determine and respond to the geometry of the display surface, and can be used in an ad-hoc cluster to create a self
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