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An Acenocoumarol Dosing Algorithm Using Clinical and Pharmacogenetic Data in Spanish Patients with Thromboembolic Disease

by Alberto M. Borobia, Rubin Lubomirov, Alicia Lorenzo, O Campos, Antonio J. Carcas
"... Appropriate dosing of coumarins is difficult to establish, due to significant inter-individual variability in the dose required to obtain stable anticoagulation. Several genetic and other clinical factors have been associated with the coumarins dose, and some pharmacogenetic-guided dosing algorithms ..."
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algorithms for warfarin and acenocoumarol have been developed for mixed populations. We recruited 147 patients with thromboembolic disease who were on stable doses and with an international normalized ratio (INR) between 2 and 3. We ascertained the influence of clinical and genetic variables on the stable

synthase and

by Laura Strittmatter, Yang Li, Nathan J. Nakatsuka, Sarah E. Calvo, Zenon Grabarek, Vamsi K. Mootha , 2013
"... is a polymorphic human enzyme with malate ..."
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is a polymorphic human enzyme with malate

unknown title

by Helena Susana, Afonso Alves, Helena Susana, Afonso Alves , 2011
"... Corporate Governance determinants of voluntary disclosure and its effects on information asymmetry: an analysis for Iberian Peninsula listed companies. ..."
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Corporate Governance determinants of voluntary disclosure and its effects on information asymmetry: an analysis for Iberian Peninsula listed companies.

AND MATHEMATICAL ENGINEERING

by Madeleine Udell, Professor Lester Mackey , 2015
"... ii ..."
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Abstract not found

unknown title

by Laura Strittmatter, Yang Li, Nathan Nakatsuka, Sarah Calvo
"... CLYBL is a polymorphic human enzyme with malate synthase and -methylmalate synthase activity ..."
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CLYBL is a polymorphic human enzyme with malate synthase and -methylmalate synthase activity

Perspective An Online Bioinformatics Curriculum

by David B. Searls
"... Abstract: Online learning initia-tives over the past decade have become increasingly comprehen-sive in their selection of courses and sophisticated in their presen-tation, culminating in the recent announcement of a number of consortium and startup activities that promise to make a university educat ..."
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Abstract: Online learning initia-tives over the past decade have become increasingly comprehen-sive in their selection of courses and sophisticated in their presen-tation, culminating in the recent announcement of a number of consortium and startup activities that promise to make a university

von

by Mathematisch-naturwissenschaftlichen Fakultät, Stefan Lange, Prof Dr, Jan-hendrik Olbertz, Prof Dr, Elmar Kulke
"... eingereicht an der ..."
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eingereicht an der

Tol2 transposon-mediated enhancer trap to identify developmentally regulated zebrafish genes in vivo.

by Serguei Parinov , Igor Kondrichin , Vladimir Korzh , Alexander Emelyanov - Dev. Dyn. , 2004
"... We have used the Tol2 transposable element to design and perform effective enhancer trapping in zebrafish. Modified transposon DNA and transposase RNA were delivered into zebrafish embryos by microinjection to produce heritable insertions in the zebrafish genome. The enhancer trap construct carries ..."
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Out-cross of the ET7-1 line produced 50% GFP-positive offspring with identical expression, suggesting that it carried a single insertion. It was confirmed by Southern blot hybridization with GFP-specific probe ( Genetic Analysis of F2 Generation F 2 fish were raised and out-crossed to wild-type fish

among Italian horse breeds

by Mitochondrial D-loop Sequence Variation, Maria Cristina Cozzi A, Paolo Valiati A, Barbarabighignoli A, Mariocancedda B, Marta Zanotti A , 2003
"... Abstract – The genetic variability of the mitochondrial D-loop DNA sequence in seven horse breeds bred in Italy (Giara, Haflinger, Italian trotter, Lipizzan, Maremmano, Thoroughbred and Sarcidano) was analysed. Five unrelated horses were chosen in each breed and twenty-two haplotypes were identified ..."
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identified. The sequences obtained were aligned and compared with a reference sequence and with 27 mtDNA D-loop sequences selected in the GenBank database, representing Spanish, Portuguese, North African, wild horses and an Equus asinus sequence as the outgroup. Kimura two-parameter distances were calculated

ields

by unknown authors
"... nite ..."
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