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248,376
Using Bayesian networks to analyze expression data
 Journal of Computational Biology
, 2000
"... DNA hybridization arrays simultaneously measure the expression level for thousands of genes. These measurements provide a “snapshot ” of transcription levels within the cell. A major challenge in computational biology is to uncover, from such measurements, gene/protein interactions and key biologica ..."
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Cited by 1076 (18 self)
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biological features of cellular systems. In this paper, we propose a new framework for discovering interactions between genes based on multiple expression measurements. This framework builds on the use of Bayesian networks for representing statistical dependencies. A Bayesian network is a graphbased model
Bayesian Network Classifiers
, 1997
"... Recent work in supervised learning has shown that a surprisingly simple Bayesian classifier with strong assumptions of independence among features, called naive Bayes, is competitive with stateoftheart classifiers such as C4.5. This fact raises the question of whether a classifier with less restr ..."
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Cited by 788 (23 self)
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restrictive assumptions can perform even better. In this paper we evaluate approaches for inducing classifiers from data, based on the theory of learning Bayesian networks. These networks are factored representations of probability distributions that generalize the naive Bayesian classifier and explicitly
Learning Bayesian networks: The combination of knowledge and statistical data
 Machine Learning
, 1995
"... We describe scoring metrics for learning Bayesian networks from a combination of user knowledge and statistical data. We identify two important properties of metrics, which we call event equivalence and parameter modularity. These properties have been mostly ignored, but when combined, greatly simpl ..."
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Cited by 1142 (36 self)
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We describe scoring metrics for learning Bayesian networks from a combination of user knowledge and statistical data. We identify two important properties of metrics, which we call event equivalence and parameter modularity. These properties have been mostly ignored, but when combined, greatly
Dynamic Bayesian Networks: Representation, Inference and Learning
, 2002
"... Modelling sequential data is important in many areas of science and engineering. Hidden Markov models (HMMs) and Kalman filter models (KFMs) are popular for this because they are simple and flexible. For example, HMMs have been used for speech recognition and biosequence analysis, and KFMs have bee ..."
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Cited by 758 (3 self)
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been used for problems ranging from tracking planes and missiles to predicting the economy. However, HMMs
and KFMs are limited in their “expressive power”. Dynamic Bayesian Networks (DBNs) generalize HMMs by allowing the state space to be represented in factored form, instead of as a single discrete
Sparse Bayesian Learning and the Relevance Vector Machine
, 2001
"... This paper introduces a general Bayesian framework for obtaining sparse solutions to regression and classication tasks utilising models linear in the parameters. Although this framework is fully general, we illustrate our approach with a particular specialisation that we denote the `relevance vec ..."
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Cited by 958 (5 self)
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vector machine' (RVM), a model of identical functional form to the popular and stateoftheart `support vector machine' (SVM). We demonstrate that by exploiting a probabilistic Bayesian learning framework, we can derive accurate prediction models which typically utilise dramatically fewer
Bayesian Interpolation
 Neural Computation
, 1991
"... Although Bayesian analysis has been in use since Laplace, the Bayesian method of modelcomparison has only recently been developed in depth. In this paper, the Bayesian approach to regularisation and modelcomparison is demonstrated by studying the inference problem of interpolating noisy data. T ..."
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Cited by 721 (17 self)
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Although Bayesian analysis has been in use since Laplace, the Bayesian method of modelcomparison has only recently been developed in depth. In this paper, the Bayesian approach to regularisation and modelcomparison is demonstrated by studying the inference problem of interpolating noisy data
Learning probabilistic relational models
 In IJCAI
, 1999
"... A large portion of realworld data is stored in commercial relational database systems. In contrast, most statistical learning methods work only with "flat " data representations. Thus, to apply these methods, we are forced to convert our data into a flat form, thereby losing much ..."
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Cited by 619 (31 self)
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objects. Although PRMs are significantly more expressive than standard models, such as Bayesian networks, we show how to extend wellknown statistical methods for learning Bayesian networks to learn these models. We describe both parameter estimation and structure learning — the automatic induction
A Practical Bayesian Framework for Backprop Networks
 Neural Computation
, 1991
"... A quantitative and practical Bayesian framework is described for learning of mappings in feedforward networks. The framework makes possible: (1) objective comparisons between solutions using alternative network architectures ..."
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Cited by 496 (20 self)
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A quantitative and practical Bayesian framework is described for learning of mappings in feedforward networks. The framework makes possible: (1) objective comparisons between solutions using alternative network architectures
A Bayesian method for the induction of probabilistic networks from data
 MACHINE LEARNING
, 1992
"... This paper presents a Bayesian method for constructing probabilistic networks from databases. In particular, we focus on constructing Bayesian belief networks. Potential applications include computerassisted hypothesis testing, automated scientific discovery, and automated construction of probabili ..."
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Cited by 1381 (32 self)
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This paper presents a Bayesian method for constructing probabilistic networks from databases. In particular, we focus on constructing Bayesian belief networks. Potential applications include computerassisted hypothesis testing, automated scientific discovery, and automated construction
Estimating Continuous Distributions in Bayesian Classifiers
 In Proceedings of the Eleventh Conference on Uncertainty in Artificial Intelligence
, 1995
"... When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon the normality ..."
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Cited by 489 (2 self)
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When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated by a single Gaussian. In this paper we abandon
Results 1  10
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248,376