methods during runtime that respect users ’ current privacy preferences as well as the prevailing privacy laws and regulations. One major concern about our approach is its performance since dynamic architectural reconfiguration during runtime is usually resource-intensive. In this paper, we describe four

as operational expenditures for hardware and software. Various distinct architectures are introduced and discussed according to their security and privacy capabilities and prospects. It provides four distinct models in form of abstracted multicloud architectures. These developed multi cloud architectures allow

to meaningful events in a timely manner. Smart supply chains fusing dynamic sensor data with information provided by backend-systems are one such example of event-based enterprise systems. Monitoring their global state in an effective way for runtime governance remains an open research challenge: providing

In presenting this thesis in partial fulfilment of the requirements for a Postgraduate degree

I herewith certify that all material in this dissertation which is not my own work has been properly acknowledged.

in partial ful2llment of the requirements for the degree of

First, I would like to thank to Dimka Karastoyanova and Mariano Cilia for all the fruitful discussions, their guidance and support through the course of this project. Thanks also to Prof. Alejandro Buchmann who sponsored my stay at Technische Universität Darmstadt during the spring of 2004. The special thanks go to my advisor, Mariano Cilia, who has made all this possible. Finally, I’d like to thank to my family for all these years of support.

This Open Access Dissertation is brought to you for free and open access by the Dissertations and Theses at ScholarWorks@UMass Amherst. It has

transmissions (EFT) and MAC3, for runtime estimation of bursty wireless links.We introduce a bursty link estimator (BLE) that based on these twometrics, accurately estimates bursty links in the network rendering them available for data transmissions. Finally, we present bursty routing extensions (BRE

Abstract: Online learning initia-tives over the past decade have become increasingly comprehen-sive in their selection of courses and sophisticated in their presen-tation, culminating in the recent announcement of a number of consortium and startup activities that promise to make a university education on the internet, free of charge, a real possibility. At this pivotal moment it is appropriate to explore the potential for obtaining comprehensive bioinformatics training with currently existing free video resources. This article pre-sents such a bioinformatics curric-ulum in the form of a virtual course catalog, together with editorial commentary, and an assessment of strengths, weaknesses, and likely future directions for open online learning in this field. Online Learning Comes of Age Online academic ‘‘courseware’ ’ at the university level has now been available to the public for a decade, the earliest concerted effort having originated in 2002 with the Massachusetts Institute of Technology (MIT) and their OpenCour-seWare initiative