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Approximation algorithms for minimum PCR primer set selection with amplification length and uniqueness constraints
 ACM Computing Research Repository
"... A critical problem in the emerging highthroughput genotyping protocols is to minimize the number of polymerase chain reaction (PCR) primers required to amplify the single nucleotide polymorphism loci of interest. In this paper we study PCR primer set selection with amplification length and uniquene ..."
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Cited by 1 (1 self)
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and uniqueness constraints from both theoretical and practical perspectives. We give a greedy algorithm that achieves a logarithmic approximation factor for the problem of minimizing the number of primers subject to a given upperbound on the length of PCR amplification products. We also give, using randomized
Approximate Signal Processing
, 1997
"... It is increasingly important to structure signal processing algorithms and systems to allow for trading off between the accuracy of results and the utilization of resources in their implementation. In any particular context, there are typically a variety of heuristic approaches to managing these tra ..."
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Cited by 516 (2 self)
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number of ideas and approaches to approximate processing as currently being formulated in the computer science community. We then present four examples of signal processing algorithms/systems that are structured with these goals in mind. These examples may be viewed as partial inroads toward the ultimate
An iterative thresholding algorithm for linear inverse problems with a sparsity constraint
, 2008
"... ..."
The space complexity of approximating the frequency moments
 JOURNAL OF COMPUTER AND SYSTEM SCIENCES
, 1996
"... The frequency moments of a sequence containing mi elements of type i, for 1 ≤ i ≤ n, are the numbers Fk = �n i=1 mki. We consider the space complexity of randomized algorithms that approximate the numbers Fk, when the elements of the sequence are given one by one and cannot be stored. Surprisingly, ..."
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Cited by 855 (12 self)
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The frequency moments of a sequence containing mi elements of type i, for 1 ≤ i ≤ n, are the numbers Fk = �n i=1 mki. We consider the space complexity of randomized algorithms that approximate the numbers Fk, when the elements of the sequence are given one by one and cannot be stored. Surprisingly
Planning Algorithms
, 2004
"... This book presents a unified treatment of many different kinds of planning algorithms. The subject lies at the crossroads between robotics, control theory, artificial intelligence, algorithms, and computer graphics. The particular subjects covered include motion planning, discrete planning, planning ..."
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Cited by 1108 (51 self)
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This book presents a unified treatment of many different kinds of planning algorithms. The subject lies at the crossroads between robotics, control theory, artificial intelligence, algorithms, and computer graphics. The particular subjects covered include motion planning, discrete planning
The Viterbi algorithm
 Proceedings of the IEEE
, 1973
"... vol. 6, no. 8, pp. 211220, 1951. [7] J. L. Anderson and J. W..Ryon, “Electromagnetic radiation in accelerated systems, ” Phys. Rev., vol. 181, pp. 17651775, 1969. [8] C. V. Heer, “Resonant frequencies of an electromagnetic cavity in an accelerated system of reference, ” Phys. Reu., vol. 134, pp. A ..."
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Cited by 985 (3 self)
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vol. 6, no. 8, pp. 211220, 1951. [7] J. L. Anderson and J. W..Ryon, “Electromagnetic radiation in accelerated systems, ” Phys. Rev., vol. 181, pp. 17651775, 1969. [8] C. V. Heer, “Resonant frequencies of an electromagnetic cavity in an accelerated system of reference, ” Phys. Reu., vol. 134, pp. A799A804, 1964. [9] T. C. Mo, “Theory of electrodynamics in media in noninertial frames and applications, ” J. Math. Phys., vol. 11, pp. 25892610, 1970.
Wrappers for Feature Subset Selection
 AIJ SPECIAL ISSUE ON RELEVANCE
, 1997
"... In the feature subset selection problem, a learning algorithm is faced with the problem of selecting a relevant subset of features upon which to focus its attention, while ignoring the rest. To achieve the best possible performance with a particular learning algorithm on a particular training set, a ..."
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Cited by 1522 (3 self)
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In the feature subset selection problem, a learning algorithm is faced with the problem of selecting a relevant subset of features upon which to focus its attention, while ignoring the rest. To achieve the best possible performance with a particular learning algorithm on a particular training set
Improved algorithms for multiplex PCR primer set selection with amplification length constraints
 Proc. 3rd AsiaPacific Bioinformatics Conference (APBC
, 2005
"... Numerous highthroughput genomics assays require the amplification of a large number of genomic loci of interest. Amplification is costeffectively achieved using several short singlestranded DNA sequences called primers and polymerase enzyme in a reaction called multiplex polymerase chain reaction ..."
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Cited by 6 (3 self)
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is that the distance between the binding sites of the two primers should not exceed a certain threshold. In this paper we study MPPCR primer set selection with amplification length constraints from both theoretical and practical perspectives. Our contributions include an improved analysis of a simple yet effective
Irrelevant Features and the Subset Selection Problem
 MACHINE LEARNING: PROCEEDINGS OF THE ELEVENTH INTERNATIONAL
, 1994
"... We address the problem of finding a subset of features that allows a supervised induction algorithm to induce small highaccuracy concepts. We examine notions of relevance and irrelevance, and show that the definitions used in the machine learning literature do not adequately partition the features ..."
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Cited by 741 (26 self)
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into useful categories of relevance. We present definitions for irrelevance and for two degrees of relevance. These definitions improve our understanding of the behavior of previous subset selection algorithms, and help define the subset of features that should be sought. The features selected should depend
Verb Semantics And Lexical Selection
, 1994
"... ... structure. As Levin has addressed (Levin 1985), the decomposition of verbs is proposed for the purposes of accounting for systematic semanticsyntactic correspondences. This results in a series of problems for MT systems: inflexible verb sense definitions; difficulty in handling metaphor and new ..."
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Cited by 520 (4 self)
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and new usages; imprecise lexical selection and insufficient system coverage. It seems one approach is to apply probability methods and statistical models for some of these problems. However, the question reminds: has PSR exhausted the potential of the knowledgebased approach? If not, are there any
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