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Results 1 - 10
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15
Implantable Neural Probes for Chronic Electrical Recording and Optical Stimulation (Invited)
"... In order to advance the understanding of brain functions, it is critical to manipulate and monitor the neural circuitry in the cellular level. Supporting optogenetics, silicon probes with monolithically integrated waveguides and electrodes were designed and validated with in-vivo recording of photo- ..."
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In order to advance the understanding of brain functions, it is critical to manipulate and monitor the neural circuitry in the cellular level. Supporting optogenetics, silicon probes with monolithically integrated waveguides and electrodes were designed and validated with in-vivo recording of photo
microelectrode/microelectronic hybrid device for brain implantable neuroprosthesis applications
- IEEE Trans. Biomed. Eng
, 2004
"... Abstract—We have designed, fabricated, and characterized a microminiaturized “neuroport ” for brain implantable neuroprosthesis applications, using an analog CMOS integrated circuit and a silicon based microelectrode array. An ultra-low power, low-noise CMOS preamplifier array with integral multiple ..."
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Cited by 16 (0 self)
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multiplexing was designed to accommodate stringent thermal and electrophysiological requirements for implantation in the brain, and a hybrid integration approach was developed to fabricate a functional microminiaturized neuroprobe device. Measurements showed that our fully scalable 16-channel CMOS amplifier
Integrated parylene-cabled silicon probes for neural prosthetics
- in IEEE Conference on Micro Electro Mechanical Systems
, 2008
"... Recent advances in the field of neural prosthetics have demonstrated the thought control of a computer cursor. This capability relies primarily on electrode array surgically implanted into the brain as an acquisition source of neural activity. Various technologies have been developed for signal extr ..."
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Cited by 2 (2 self)
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Recent advances in the field of neural prosthetics have demonstrated the thought control of a computer cursor. This capability relies primarily on electrode array surgically implanted into the brain as an acquisition source of neural activity. Various technologies have been developed for signal
Probing the electrode-neuron interface with focused cochlear implant stimulation
- Trends in Amplification
, 2010
"... Cochlear implants are highly successful neural prostheses for persons with severe or profound hearing loss who gain little benefit from hearing aid amplification. Although implants are capable of providing important spectral and temporal cues for speech perception, performance on speech tests is var ..."
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Cited by 1 (1 self)
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is variable across listeners. Psychophysical measures obtained from indi-vidual implant subjects can also be highly variable across implant channels. This review discusses evidence that such variability reflects deviations in the electrode–neuron interface, which refers to an implant channel’s ability
The Open Ophthalmology Journal, 2008, 2, 77-90 77 High Resolution Implantable Microsystem and Probe Design for Retinal
"... Abstract: By a retinal prosthesis, the researchers have been able to stimulate a limited number of neurons (around 100) by biphasic current stimulus to reproduce an image spatially by multiplexing technique. For functional restoration of sight (visual acuity 20/80), we are to stimulate at least 2500 ..."
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. To address this problem, we have designed high resolution donut probes and used them in designing neural implant chip (NIC) applying parallel multiplexing technique, which helped us stimulate large number of neurons. This paper presents the design of a donut probe and an implantable CMOS-based 5x5 array NIC
Intracellular Recording with Low-power Low-noise CMOS Voltage and Current Clamp Circuits
, 2007
"... The measurement and processing of electrophysiological signals is a fun-damental task performed by neuroscientists, as a means to gaining an insight into how biological systems respond to external stimuli and communicate with each other. Recently, the advent of microelectrode arrays has created the ..."
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the need to design low-power implantable electronic systems that are capa-ble of recording neural activity while not causing permanent damage to the neural systems under observation. Such systems would prove invaluable in furthering our understanding of the electrical function of neurons in regard to drug
A Low Power Biochip for High Density Spatial Recording of Neural Signals
"... The development of a custom ASIC is presented that can provide unobtrusive imaging of neural activity in either an in vivo or in vitro environment. The device operates by amplification and analogue signal conditioning of the small neural signals (10s- 100s µV) detected at the electrode transducers a ..."
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The development of a custom ASIC is presented that can provide unobtrusive imaging of neural activity in either an in vivo or in vitro environment. The device operates by amplification and analogue signal conditioning of the small neural signals (10s- 100s µV) detected at the electrode transducers
Effects of electrode design and configuration on channel interactions
, 2006
"... A potential shortcoming of existing multichannel cochlear implants is electrical-field summation during simultaneous electrode stimulation. Electrical-field interactions can disrupt the stimulus waveform prior to neural activation. To test whether speech intelligibility can be degraded by electrical ..."
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Cited by 8 (1 self)
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A potential shortcoming of existing multichannel cochlear implants is electrical-field summation during simultaneous electrode stimulation. Electrical-field interactions can disrupt the stimulus waveform prior to neural activation. To test whether speech intelligibility can be degraded
Investigation of a New Electrode Array Technology for a Central Auditory Prosthesis
"... Ongoing clinical studies on patients recently implanted with the auditory midbrain implant (AMI) into the inferior colliculus (IC) for hearing restoration have shown that these patients do not achieve performance levels comparable to cochlear implant patients. The AMI consists of a single-shank arra ..."
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performed experiments in ketamine-anesthetized guinea pigs in which we inserted and stimulated a NeuroProbes array within the IC and recorded the corresponding neural activation within the auditory cortex. We used 2-D arrays for this initial feasibility study since they were already available and were
Brain Machine Interfaces combining Microelectrode Arrays with Nanostructured Optical Biochemical Sensors
"... Neural microelectrodes are an important component of neural prosthetic systems which assist paralyzed patients by allowing them to operate computers or robots using their neural activity. These microelectrodes are also used in clinical settings to localize the locus of seizure initiation in epilepsy ..."
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novel elongated multi-site neural electrodes that can record electrical signals and specific neural biomarkers and that can reach depths greater than 8mm in the sulcus of non-human primates (monkeys). We hypothesize that additional signals recorded by the multimodal probes will increase the information
Results 1 - 10
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15
