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A Survey of Evolution Strategies

by Thomas Bäck, Frank Hoffmeister, Hans-Paul Schwefel - Proceedings of the Fourth International Conference on Genetic Algorithms , 1991
"... Similar to Genetic Algorithms, Evolution Strategies (ESs) are algorithms which imitate the principles of natural evolution as a method to solve parameter optimization problems. The development of Evolution Strategies from the first mutation--selection scheme to the refined (¯,)--ES including the gen ..."
Abstract - Cited by 263 (3 self) - Add to MetaCart
Similar to Genetic Algorithms, Evolution Strategies (ESs) are algorithms which imitate the principles of natural evolution as a method to solve parameter optimization problems. The development of Evolution Strategies from the first mutation--selection scheme to the refined (¯,)--ES including

Tackling real-coded genetic algorithms: operators and tools for the behavioural analysis

by F. Herrera, M. Lozano, J. L. Verdegay - Arti Intelligence Reviews , 1998
"... Abstract. Genetic algorithms play a significant role, as search techniques for handling com-plex spaces, in many fields such as artificial intelligence, engineering, robotic, etc. Genetic algorithms are based on the underlying genetic process in biological organisms and on the natural evolution prin ..."
Abstract - Cited by 198 (27 self) - Add to MetaCart
principles of populations. These algorithms process a population of chromo-somes, which represent search space solutions, with three operations: selection, crossover and mutation. Under its initial formulation, the search space solutions are coded using the binary alphabet. However, the good properties

Competition for consciousness among visual events: the Psychophysics of reentrant visual processes

by Vincent Di Lollo, James T. Enns, Ronald A. Rensink - Journal of Experimental Psychology: General , 2000
"... Advances in neuroscience implicate reentrant signaling as the predominant form of communication between brain areas. This principle was used in a series of masking experiments that defy explanation by feed-forward theories. The masking occurs when a brief display of target plus mask is continued wit ..."
Abstract - Cited by 184 (18 self) - Add to MetaCart
-forward views based on inhibitory contour interactions. From the time a stimulus first enters the eye to the time a percept emerges into consciousness, the initial stimulus has been coded at several levels in the visual system. One of the main goals in studying visual information processing is to specify

From Boolean to Probabilistic Boolean Networks as Models of Genetic Regulatory Networks

by Ilya Shmulevich, Edward R. Dougherty, Wei Zhang - Proc. IEEE , 2002
"... Mathematical and computational modeling of genetic regulatory networks promises to uncover the fundamental principles governing biological systems in an integrarive and holistic manner. It also paves the way toward the development of systematic approaches for effective therapeutic intervention in di ..."
Abstract - Cited by 124 (23 self) - Add to MetaCart
in disease. The central theme in this paper is the Boolean formalism as a building block for modeling complex, large-scale, and dynamical networks of genetic interactions. We discuss the goals of modeling genetic networks as well as the data requirements. The Boolean formalism is justified from several

A comparison of genetic network models

by E P Van Someren , Lfa Wessels , E Backer , Mjt Reinders - In Pac. Symp. Biocomputing , 2001
"... The inference of genetic interactions from measured expression data is one of the most challenging tasks of modern functional genomics. When successful, the learned network of regulatory interactions yields a wealth of useful information. An inferred genetic network contains information about the p ..."
Abstract - Cited by 97 (5 self) - Add to MetaCart
enzyme in such a pathway did not lead to the desired effect We know that the structure of complex genetic and biochemical networks lies hidden in the sequence information of our DNA but it is far from trivial to predict gene expression from the sequence code alone. The current availability of microarray

TO CODE OR NOT TO CODE

by Présentée À La, Faculté Informatique, Et Communications, Section Des, Systèmes De Communication, Du Grade, De Docteur, Ès Sciences, Prof M. Vetterli, Prof B. Rimoldi, Prof R. Gallager, Prof A. Lapidoth, Prof J. Massey, Prof E. Telatar, Prof S. Verdú, Michael Gastpar, Amos Lapidoth, Jim Ma , 2002
"... de nationalité suisse et originaire de Zurich (ZH) et Lucerne (LU) acceptée sur proposition du jury: ..."
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de nationalité suisse et originaire de Zurich (ZH) et Lucerne (LU) acceptée sur proposition du jury:

Synonymous but not the same: The causes and consequences of codon bias.

by Joshua B Plotkin , Grzegorz Kudla - Nat Rev Genet , 2010
"... When the inherent redundancy of the genetic code was discovered, scientists were rightly puzzled by the role of synonymous mutations 1 . The central dogma of molecular biology suggests that synonymous mutations -those that do not alter the encoded amino acid -will have no effect on the resulting pr ..."
Abstract - Cited by 133 (0 self) - Add to MetaCart
When the inherent redundancy of the genetic code was discovered, scientists were rightly puzzled by the role of synonymous mutations 1 . The central dogma of molecular biology suggests that synonymous mutations -those that do not alter the encoded amino acid -will have no effect on the resulting

Understanding hierarchical protein evolution from first principles

by Nikolay V. Dokholyan, Eugene I. Shakhnovich - J. Mol. Biol , 2001
"... We propose a model that explains the hierarchical organization of proteins in fold families. The model, which is based on the evolutionary selection of proteins by their native state stability, reproduces patterns of amino acids conserved across protein families. Due to its dynamic nature, the model ..."
Abstract - Cited by 22 (6 self) - Add to MetaCart
, the model sheds light on the evolutionary time-scales. By studying the relaxation of the correlation function between consecutive mutations at a given position in proteins, we observe separation of the evolutionary time-scales: at short time intervals families of proteins with similar sequences

Synonymous and Nonsynonymous Rate Variation in Nuclear Genes of Mammals

by Ziheng Yang, Rasmus Nielsen - Journal of Molecular Evolution , 1998
"... A maximum likelihood approach was used to estimate the synonymous and nonsynonymous substitution rates in 48 nuclear genes from primates, artiodactyls, and rodents. A codon-substitution model was assumed, which accounts for the genetic code structure, transition/transversion bias, and base frequency ..."
Abstract - Cited by 120 (10 self) - Add to MetaCart
A maximum likelihood approach was used to estimate the synonymous and nonsynonymous substitution rates in 48 nuclear genes from primates, artiodactyls, and rodents. A codon-substitution model was assumed, which accounts for the genetic code structure, transition/transversion bias, and base

From quantum groups to genetic mutations

by A. Sciarrino, Complesso Universitario, Monte S. Angelo , 2003
"... In the framework of the crystal basis model of the genetic code, where each codon is assigned to an irreducible representation of Uq→0(sl(2) ⊕sl(2)), single base mutation matrices are introduced. The strength of the mutation is assumed to depend on the “distance ” between the codons. Preliminary gen ..."
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In the framework of the crystal basis model of the genetic code, where each codon is assigned to an irreducible representation of Uq→0(sl(2) ⊕sl(2)), single base mutation matrices are introduced. The strength of the mutation is assumed to depend on the “distance ” between the codons. Preliminary
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