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2,383
MetaFluxNet, a Program Package for Metabolic Pathway Construction and Analysis, and Its Use in Large-Scale Metabolic Flux Analysis of Escherichia coli
, 2003
"... We have developed MetaFluxNet which is a stand-alone program package for the management of metabolic reaction information and quantitative metabolic flux analysis. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental modifications. ..."
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Cited by 2 (0 self)
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We have developed MetaFluxNet which is a stand-alone program package for the management of metabolic reaction information and quantitative metabolic flux analysis. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental modifications.
Regulation of Circadian Behavior and Metabolism by Synthetic
"... Synchronizing rhythms of behavior and metabolic processes is important for cardiovascular health and preventing metabolic diseases. The nuclear receptors REV-ERBα and REV-ERBβ play an integral role in regulating the expression of core clock proteins driving rhythms in activity and metabolism. Here w ..."
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Synchronizing rhythms of behavior and metabolic processes is important for cardiovascular health and preventing metabolic diseases. The nuclear receptors REV-ERBα and REV-ERBβ play an integral role in regulating the expression of core clock proteins driving rhythms in activity and metabolism. Here
MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis
- BIOINFORMATICS
, 2003
"... Summary: MetaFluxNet is a program package for managing information on the metabolic reaction network and for quantitatively analyzing metabolic fluxes in an interactive and customized way. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental modific ..."
Abstract
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Cited by 17 (6 self)
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Summary: MetaFluxNet is a program package for managing information on the metabolic reaction network and for quantitatively analyzing metabolic fluxes in an interactive and customized way. It allows users to interpret and examine metabolic behavior in response to genetic and/or environmental
1 Adaptivity: From Metabolism to Behavior
"... In this article, we propose some fundamental requirements for the appearance of adaptivity. We argue that a basic metabolic organization, taken in its minimal sense, may provide the conceptual framework for naturalizing the origin of teleology and normative functionality as it appears in living syst ..."
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In this article, we propose some fundamental requirements for the appearance of adaptivity. We argue that a basic metabolic organization, taken in its minimal sense, may provide the conceptual framework for naturalizing the origin of teleology and normative functionality as it appears in living
The metabolism of low density lipoprotein in familial type II
"... tein (LDL, beta lipoprotein) was studied in 10 normal individuals and 10 patients with familial type II hyper-lipoproteinemia using purified radioiodinated LDL. Over 97 % of the label was bound to the protein moiety of LDL and therefore the turnover data reflect the fate and distribution of LDL-apop ..."
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Cited by 38 (1 self)
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-apoprotein. Comparison of the metabolic behavior of biologically screened and utn-screened labeled LDL preparations in dogs as well as the analysis of the urinary excretion of radioiodide de-rived from labeled LDL degradation in humans indicated that no significant denaturation resulted from the iso-lation, purification
Computational genetics, physiology, metabolism, neural systems, learning, vision, and behavior or PolyWorld: Life in a new context
- Artificial Life III, Vol. XVII of SFI Studies in the Sciences of Complexity, Santa Fe Institute
, 1993
"... This paper discusses a computer model of living organisms and the ecology they exist in called PolyWorld. PolyWorld attempts to bring together all the principle components of real living systems into a single artificial (man-made) living system. PolyWorld brings together biologically motivated genet ..."
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Cited by 54 (3 self)
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genetics, simple simulated physiologies and metabolisms, Hebbian learning in arbitrary neural network architectures, a visual perceptive mechanism, and a suite of primitive behaviors in artificial organisms grounded in an ecology just complex enough to foster speciation and inter-species competition
Regulation of Gene Expression in Flux Balance Models of Metabolism
- J. Theor. Biol
, 2001
"... Genome-scale metabolic networks can now be reconstructed based on annotated genomic data augmented with biochemical and physiological information about the organism. Mathematical analysis can be performed to assess the capabilities of these reconstructed networks. The constraints-based framework, wi ..."
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Cited by 59 (7 self)
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#uence on the behavior of the organism. Thus, there is a need to include regulatory events within FBA to broaden its scope and predictive capabilities. Here we represent transcriptional regulatory events as time-dependent constraints on the capabilities of a reconstructed metabolic network to further constrain the space
Koreans: characteristics and health behaviors
"... Metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) phenotypes in ..."
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Metabolically obese but normal weight (MONW) and metabolically healthy but obese (MHO) phenotypes in
The polyvagal theory: Phylogenetic substrates of a social nervous system.
- International Journal of Psychophysiology,
, 2001
"... Abstract The evolution of the autonomic nervous system provides an organizing principle to interpret the adaptive significance of physiological responses in promoting social behavior. According to the polyvagal theory, the well-documented phylogenetic shift in neural regulation of the autonomic ner ..."
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Cited by 92 (5 self)
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nervous system passes through three global stages, each with an associated behavioral strategy. The first stage is characterized by a primitive unmyelinated visceral vagus that fosters digestion and responds to threat by depressing metabolic activity. Behaviorally, the first stage is associated
Chapter 6 A Guide to Integrating Transcriptional Regulatory and Metabolic Networks Using PROM (Probabilistic Regulation of Metabolism)
"... Abstract The integration of transcriptional regulatory and metabolic networks is a crucial step in the process of predicting metabolic behaviors that emerge from either genetic or environmental changes. Here, we present a guide to PROM (probabilistic regulation of metabolism), an automated method f ..."
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Abstract The integration of transcriptional regulatory and metabolic networks is a crucial step in the process of predicting metabolic behaviors that emerge from either genetic or environmental changes. Here, we present a guide to PROM (probabilistic regulation of metabolism), an automated method
Results 11 - 20
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2,383