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9,417
The complete genome sequence of Escherichia coli K-12
- Science
, 1997
"... The 4,639,221–base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five other sequenced microbes reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes withi ..."
Abstract
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Cited by 1129 (39 self)
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within E. coli are also evident. The largest family of paralogous proteins contains 80 ABC transporters. The genome as a whole is strikingly organized with respect to the local direction of replication; guanines, oligo-nucleotides possibly related to replication and recombination, and most genes are so
Predicting Transmembrane Protein Topology with a Hidden Markov Model: Application to Complete Genomes
- J. MOL. BIOL
, 2001
"... ..."
complete genomes
, 2007
"... Motivation: Inference of the evolutionary relation between proteins, in particular the identification of orthologs, is a central problem in comparative genomics. Several large-scale efforts with various methodologies and scope tackle this problem, including OMA (the Orthologous MAtrix project). Resu ..."
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). Results: Based on the results of the OMA project, we introduce here the OMA Browser, a web-based tool allowing the exploration of orthologous relations over 352 complete genomes. Orthologs can be viewed as groups across species, but also at the level of sequence pairs, allowing the distinction among one
Multifractal characterisation of complete genomes
- Journal of Physics A
, 2001
"... This paper develops a theory for characterisation of DNA sequences based on their measure representation. The measures are shown to be random cascades generated by an infinitely divisible distribution. This probability distribution is uniquely determined by the exponent function in the multifractal ..."
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Cited by 9 (4 self)
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theory of random cascades. Curve fitting to a large number of complete genomes of bacteria indicates that the Gamma density function provides an excellent fit to the exponent function, and hence to the probability distribution of the complete genomes. 1
Prediction of complete gene structures in human genomic DNA
- J. Mol. Biol
, 1997
"... The problem of identifying genes in genomic DNA sequences by computational methods has attracted considerable research attention in recent years. From one point of view, the problem is closely ..."
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Cited by 1177 (9 self)
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The problem of identifying genes in genomic DNA sequences by computational methods has attracted considerable research attention in recent years. From one point of view, the problem is closely
Shannon information in complete genomes
"... Shannon information in the genomes of all completely sequenced prokaryotes and eukaryotes are measured in word lengths of two to ten letters. It is found that in a scale-dependent way, the Shannon information in complete genomes are much greater than that in matching random sequences- thousands of t ..."
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Cited by 4 (0 self)
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Shannon information in the genomes of all completely sequenced prokaryotes and eukaryotes are measured in word lengths of two to ten letters. It is found that in a scale-dependent way, the Shannon information in complete genomes are much greater than that in matching random sequences- thousands
The KEGG resource for deciphering the genome
- Nucleic Acids Res
, 2004
"... A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a knowledg ..."
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Cited by 513 (24 self)
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A grand challenge in the post-genomic era is a complete computer representation of the cell and the organism, which will enable computational prediction of higher-level complexity of cellular processes and organism behavior from genomic information. Toward this end we have been developing a
The Complete Genome Sequence and Analysis of the
"... Background. Arcobacter butzleri is a member of the epsilon subdivision of the Proteobacteria and a close taxonomic relative of established pathogens, such as Campylobacter jejuni and Helicobacter pylori. Here we present the complete genome sequence of the human clinical isolate, A. butzleri strain R ..."
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Background. Arcobacter butzleri is a member of the epsilon subdivision of the Proteobacteria and a close taxonomic relative of established pathogens, such as Campylobacter jejuni and Helicobacter pylori. Here we present the complete genome sequence of the human clinical isolate, A. butzleri strain
Based on Complete Genome Analyses
, 2004
"... Human papillomavirus type 16 (HPV16) is the primary etiological agent of cervical cancer, the second most common cancer in women worldwide. Complete genomes of 12 isolates representing the major lineages of HPV16 were cloned and sequenced from cervicovaginal cells. The sequence variations within the ..."
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Human papillomavirus type 16 (HPV16) is the primary etiological agent of cervical cancer, the second most common cancer in women worldwide. Complete genomes of 12 isolates representing the major lineages of HPV16 were cloned and sequenced from cervicovaginal cells. The sequence variations within
Complete Genome Sequence of the Extreme Thermophile
"... Here, we present the complete genome of the extreme thermophile,Dictyoglomus thermophilumH-6-12 (phylumDictyoglomi), which consists of 1,959,987 bp. ..."
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Here, we present the complete genome of the extreme thermophile,Dictyoglomus thermophilumH-6-12 (phylumDictyoglomi), which consists of 1,959,987 bp.
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