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Behavioral theories and the neurophysiology of reward,
- Annu. Rev. Psychol.
, 2006
"... ■ Abstract The functions of rewards are based primarily on their effects on behavior and are less directly governed by the physics and chemistry of input events as in sensory systems. Therefore, the investigation of neural mechanisms underlying reward functions requires behavioral theories that can ..."
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Cited by 187 (0 self)
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to subjective feelings of liking and pleasure. You do something again because it produced a pleasant outcome before. We refer to this as the hedonic function of rewards. The following descriptions will show that both of these perceptions of reward fall well short of providing a complete and coherent description
Gender and Age Influences on Human Brain Mu-Opioid Receptor Binding Measured by PET
"... Objective: Both age and gender are being increasingly recognized as important factors influencing CNS structure and function. However, there are relatively few data on actual neurochemical differences between the sexes in human subjects or on their interaction with age. One of the central neurotrans ..."
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neurotransmitter systems for which sex differences have been sug-gested by animal models and clinical human data is the opioid. In this study the authors ex-amined age- and gender-associated variations in mu-opioid receptor binding with positron emission tomography (PET). Method: Healthy human subjects were
Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia.
- Neuroscience & Biobehavioral Reviews
, 1991
"... _____ KRISTAL, M.B. Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia. NEUROSCI BIOBEHAV REV 15(3) 425-435, 1991. --Two major consequences of placentophagia, the ingestion of afterbirth materials that occurs usually during mammalian parturition, have been uncovere ..."
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Cited by 8 (1 self)
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_____ KRISTAL, M.B. Enhancement of opioid-mediated analgesia: A solution to the enigma of placentophagia. NEUROSCI BIOBEHAV REV 15(3) 425-435, 1991. --Two major consequences of placentophagia, the ingestion of afterbirth materials that occurs usually during mammalian parturition, have been
 -blocker Binding to Human 5-HT 1A Receptors in vivo and in vitro : Implications for Antidepressant Therapy
, 2000
"... A novel strategy for improving the treatment of depressive illness is augmentation of antidepressants with a 5-HT1 SSRIs are increasingly used in the pharmacological treatment of depression. SSRIs specifically block 5-HT reuptake sites leading to an eventual increase of 5-HT in terminal synapses; a ..."
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Displays Differential Affinity for the 5-HT 1A Autoreceptor Compared to the Post-synaptic Receptor in vitro Pindolol, penbutolol and tertatolol displayed high affinity for 5-HT 1A binding sites in postmortem human brain sections DISCUSSION Pindolol administered acutely to healthy subjects occupies the 5
BDRS PRICE DESCRIPTOR,
"... This report focuses on the evidence about the health.consequences of smoking for women, and is intended to serve.the public health and medical communities as 'a unified source of existing scientific research. The major issues about tobacco use and women's health are examined, including tre ..."
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This report focuses on the evidence about the health.consequences of smoking for women, and is intended to serve.the public health and medical communities as 'a unified source of existing scientific research. The major issues about tobacco use and women's health are examined, including
l Article
"... Can the blind see? Blindsight is residual visual capacity in a field defect secondary to damaged striate cortex without conscious awareness. This phenomenon was discovered when patients with this form of field loss were given forced-choice testing. Although the subjects denied seeing anything, their ..."
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Can the blind see? Blindsight is residual visual capacity in a field defect secondary to damaged striate cortex without conscious awareness. This phenomenon was discovered when patients with this form of field loss were given forced-choice testing. Although the subjects denied seeing anything
Novel Therapeutic Approaches to the Treatment of Chronic Abdominal Visceral Pain
"... Chronic abdominal visceral pain (CAVP) has a significant clinical impact and represents one of the most frequent and debilitating disorders in the general population. It also leads to a significant economic burden due to workdays lost, reduced productivity, and long-term use of medications with the ..."
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with neurons, mast cells, and smooth muscle cells located in the gastrointestinal tract. Past research has identified several potential therapeutic receptors such as 5-HT3, 5-HT1A, 5-HT2B, and 5-HT4 that are associated with abdominal pain/discomfort [52]. Some serotonergic agents that are recently available
The interplay of early-life stress, nutrition, and immune activation programs adult hippocampal structure and function
"... The interplay of early-life stress, nutrition, and immune activation programs adult hippocampal structure and function Hoeijmakers, L.; Lucassen, P.J.; Korosi, A. Published in: Frontiers in Molecular Neuroscience DOI: 10.3389/fnmol.2014.00103 Link to publication Citation for published version (APA) ..."
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interact and affect one another and suggest that it is a synergistic action of these elements that shapes cognition throughout life. Finally, we consider different intervention studies aiming to prevent these early-life adversity induced consequences. The emerging evidence for the intriguing interplay
