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Actin assembly in electropermeabilized neutrophils: role of intracellular calcium

by Gregory P. Downey, Chi Kin Chan, Suzanne Trudel, Sergio Grinstein - Z Cell , 1990
"... Abstract. Assembly of microfilaments involves the conversion of actin from the monomeric (G) to the filamentous (F) form. The exact sequence of events responsible for this conversion is yet to be defined and, in particular, the role of calcium remains unclear. Intact and electropermeabilized human n ..."
Abstract - Cited by 16 (0 self) - Add to MetaCart
Abstract. Assembly of microfilaments involves the conversion of actin from the monomeric (G) to the filamentous (F) form. The exact sequence of events responsible for this conversion is yet to be defined and, in particular, the role of calcium remains unclear. Intact and electropermeabilized human

Calcium: a fundamental regulator of intracellular membrane fusion

by Jesse C Hay - EMBO Rep , 2007
"... For many years, it has been known that an increase in cytosolic calcium triggers the fusion of secretory granules and synaptic vesicles with the plasma membrane. However, the role of calcium in the intracellular membrane-fusion reactions that coordinate the secretory and endocytic pathways has been ..."
Abstract - Cited by 10 (2 self) - Add to MetaCart
For many years, it has been known that an increase in cytosolic calcium triggers the fusion of secretory granules and synaptic vesicles with the plasma membrane. However, the role of calcium in the intracellular membrane-fusion reactions that coordinate the secretory and endocytic pathways has

Chloral hydrate disrupts mitosis by increasing intracellular free calcium

by Greta M. Lee, Jim Diguiseppi, Govind M. Gawdi, Brian Herman - J. Cell Sci. 88(Pt , 1987
"... In examining how chloral hydrate affects mitosis, we found that extracellular application of 0*1 % chloral hydrate produced an abrupt rise in cytosolic free Ca2+. Digitized fluorescence microscopy of Fura-2-loaded, mitotic and inter-phase PtK cells revealed that Ca2+ rose 15 s after chloral hydrate ..."
Abstract - Cited by 4 (0 self) - Add to MetaCart
-phase, as determined by phase-contrast obser-vation of living cells. Spindle elongation and chromosome movement were unaffected by intra-cellular injection of 7-5 % chloral hydrate. Exten-sive mitotic microtubule breakdown occurred after cells were bathed for 7 min in 0-1 % chloral hydrate, while interphase

Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of

by Amyloid Neurotoxicity, Andrey Y. Abramov, Laura Canevari, Michael R. Duchen
"... Although the accumulation of the neurotoxic peptide � amyloid (�A) in the CNS is a hallmark of Alzheimer’s disease, the mechanism of �A neurotoxicity remains controversial. In cultures of mixed neurons and astrocytes, we found that both the full-length peptide �A (1 – 42) and the neurotoxic fragment ..."
Abstract - Cited by 12 (3 self) - Add to MetaCart
fragment (25–35) caused sporadic cytoplasmic calcium [intracellular calcium ([Ca 2 � ] c)] signals in astrocytes that continued for hours, whereas adjacent neurons were completely unaffected. Nevertheless, after 24 hr, although astrocyte cell death was marginally increased, �50 % of the neurons had died

Increased intracellular calcium is required for spreading of rat islet �-cells on extracellular matrix

by Domenico Bosco, Carmen Gonelle-gispert, Claes B. Wollheim, Dominique G. Rouiller - Diabetes , 2001
"... Rat islet b-cells spread in response to glucose when attached on the matrix produced by a rat bladder carci-noma cell line (804G). Furthermore, in a mixed popula-tion of cells, it has been observed previously that spread cells secrete more insulin acutely in response to glu-cose, compared with cells ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
with cells that remain rounded. These results suggest bi-directional signaling between the is-let b-cell and the extracellular matrix. In the present study, the role of increased intracellular free Ca21 concentration [Ca21]i as an intracellular step linking glucose stimulation and b-cell spreading (inside

Mechanisms Involved in the Increase in Intracellular Calcium Following Hypotonic Shock

by In Bovine Articular Chondrocytes, J. C. Sænchez, T. A. Danks, R. J. Wilkins
"... Abstract. The extracellular osmotic environment of chondrocytes fluctuates dur-ing joint loading as fluid is expressed from and reimbibed by the extracellular matrix. Matrix synthesis by chondrocytes is modulated by joint loading, possibly mediated by variations in intracellular composition. The pre ..."
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2+]i rapidly increased by approxi-mately 250%, a sustained plateau being achieved within 300 s. The eect was inhibited by thapsigargin or by removal of extracellular Ca2+, indicating that the rise in [Ca2+]i reflects both influx from the extracellular medium and release from intracellular stores

Mechanisms of lysophosphatidylcholine-induced increase in intracellular calcium in rat cardiomyocytes

by Liping Yu , Thomas Netticadan , Yan-Jun Xu , Vincenzo Panagia , Naranjan S Dhalla - Journal of Pharmacology and Experimental Therapeutics , 1998
"... ABSTRACT ..."
Abstract - Cited by 1 (0 self) - Add to MetaCart
Abstract not found

Alien intracellular calcium chelators attenuate neurotransmitter release at the squid giant synapse

by E. M. Adler, S George J. Augustine, Steven N. Duffy, Milton P. Charltons - J. Neurosci , 1991
"... A number of calcium buffers were examined for their ability to reduce evoked transmitter release when injected into the presynaptic terminal of the squid giant synapse. Injection of EGTA was virtually ineffective at reducing transmitter re-lease, even at estimated intracellular concentrations up to ..."
Abstract - Cited by 25 (0 self) - Add to MetaCart
A number of calcium buffers were examined for their ability to reduce evoked transmitter release when injected into the presynaptic terminal of the squid giant synapse. Injection of EGTA was virtually ineffective at reducing transmitter re-lease, even at estimated intracellular concentrations up

Intercellular communication via intracellular calcium oscillations

by M. E. Gracheva, J. D. Gunton - J. Theor. Biol , 2003
"... In this letter we present the results of a simple model for intercellular communication via calcium oscillations, motivated in part by a recent experimental study. The model describes two cells (a ”donor ” and ”sensor”) whose intracellular dynamics involve a calcium-induced, calcium release process. ..."
Abstract - Cited by 4 (1 self) - Add to MetaCart
In this letter we present the results of a simple model for intercellular communication via calcium oscillations, motivated in part by a recent experimental study. The model describes two cells (a ”donor ” and ”sensor”) whose intracellular dynamics involve a calcium-induced, calcium release process

Btk/Tec kinases regulate sustained increases in intracellular Ca21 following B-cell receptor activation

by Anne-catherine Fluckiger, Zuomei Li, Roberta M. Kato, Matthew I. Wahl, Hans D. Ochs, Richard Longnecker, Jean-pierre Kinet, Owen N. Witte, Andrew M. Scharenberg, David J. Rawlings , 1998
"... A.-C.Fluckiger and Z.Li contributed equally to this work Bruton’s tyrosine kinase (Btk) is essential for B-lineage development and represents an emerging family of non-receptor tyrosine kinases implicated in signal transduction events initiated by a range of cell surface receptors. Increased dosage ..."
Abstract - Cited by 45 (5 self) - Add to MetaCart
A.-C.Fluckiger and Z.Li contributed equally to this work Bruton’s tyrosine kinase (Btk) is essential for B-lineage development and represents an emerging family of non-receptor tyrosine kinases implicated in signal transduction events initiated by a range of cell surface receptors. Increased dosage
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