This book is printed on acid-free paper.

This book is printed on acid-free paper.

This book is printed on acid-free paper.

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Objective: To create an evidence-based position statement regarding the treatment of vasomotor symptoms associated with menopause. Design: The North American Menopause Society (NAMS) enlisted clinicians and researchers acknowledged to be experts in the field of menopause-associated vasomotor symptoms to review the evidence obtained from the medical literature and develop a document for final approval by the NAMS Board of Trustees. Results: For mild hot flashes, lifestyle-related strategies such as keeping the core body temperature cool, participating in regular exercise, and using paced respiration have shown some efficacy without adverse effects. Among nonprescription remedies, clinical trial results are insufficient to either support or refute efficacy for soy foods and isoflavone supplements (from either soy or red clover), black cohosh, or vitamin E; however, no serious side effects have been associated with short-term use of these therapies. Single clinical trials have found no benefit for dong quai, evening primrose oil, ginseng, a Chinese herbal mixture, acupuncture, or magnet therapy. Few data support the efficacy of topical progesterone cream; safety concerns should be the same as for other progestogen

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In association with The Society for Assisted Reproductive Technology (SART) and RAND Objective: To determine the number of embryos stored at assisted reproductive technology (ART) clinics in the United States and their current disposition. Design: A targeted survey instrument sent by the SART–RAND team to all medical practices providing in vitro fertilization services in the United States. Result(s): The SART–RAND team surveyed all 430 ART practices in the United States. Of these practices, 340 returned surveys for analysis. The data from these surveys were merged with data taken from the 1999 SART dataset, which contains information about practice size and success rates. Responding clinics reported a total of 396,526 embryos in storage as of April 11, 2002. The vast majority of the embryos (88.2%) were targeted for patient use. Small numbers of embryos were available for research, donation, destruction, quality assurance, or other uses. Conclusion(s): Nearly 400,000 embryos are stored in the United States, the majority of which (88.2%) are targeted for patient use. Few are available for research (2.8%), limiting possible conversion into embryonic stem cell lines. (Fertil Steril � 2003;79:1063–9. ©2003 by American Society for Reproductive Medicine.) Key Words: IVF, ART, cryopreserved embryos, cryopreservation, stem cells Received January 16, 2003; revised and accepted January 16,

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