THE EFFECTS OF DIETARY PHOSPHORUS AND PARATHYROID HORMONE (PTH) INFUSION RATES ON THE AVIAN PHOSPHATURIC RESPONSE TO PTH (1989)
BibTeX
@MISC{Stanton89theeffects,
author = {S. Stanton and Raymond P. Glahn and Robert and F. Wideman},
title = {THE EFFECTS OF DIETARY PHOSPHORUS AND PARATHYROID HORMONE (PTH) INFUSION RATES ON THE AVIAN PHOSPHATURIC RESPONSE TO PTH},
year = {1989}
}
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Abstract
Experiments were performed to evaluate the effects of dietary available phosphorus (aP) and PTH infusion rates on avian urinary inorganic phosphate (Pi) excretion. In experiment I, female domestic fowl were fed diets containing low (0-45%) or high (0-83%) aP for 2-4 weeks prior to renal function studies. Pi excretion was significantly higher for birds fed the high-aP diet than for birds fed the low-aP diet. PTH was infused (60-240 units kg body mass " 1 h " 1) unilaterally into the renal portal system. Para-aminohippuric acid (PAH), included in the unilateral infusate as a marker for effective renal portal perfusion, indicated that PTH.must have been delivered to the peritubular surfaces of the infused kidney. However, bilateral but not unilateral phosphaturia occurred, and there were no significant differences in the phosphaturic responses to PTH when low- and highaP diet treatment groups were compared. In experiment II, PTH was infused at rates of l-Sunitsh " 1. Infusing PTH at 5unitsh-1 caused a unilateral increase in urine flow but the phosphaturic response was still bilateral. It appears unlikely that unilateral renal portal PTH infusions can be used to trigger unilateral phosphaturia in domestic fowl.
Keyphrases
infusion rate avian phosphaturic response pth effect dietary phosphorus parathyroid hormone unilateral phosphaturia phosphaturic response significant difference urine flow body mass quot renal function study 60-240 unit infused kidney unilateral renal portal pth infusion pth infusion rate domestic fowl female domestic fowl avian urinary inorganic phosphate 2-4 week effective renal portal perfusion para-aminohippuric acid experiment ii highap diet treatment group low-ap diet pi excretion dietary available phosphorus peritubular surface unilateral infusate renal portal system unilateral increase high-ap diet l-sunitsh quot
