mitochondrial Oxa1p, is a component of the Sec translocase Koch et al., 1999), although the exact subset of innerPier A.Scotti, Malene L.Urbanus, membrane proteins that depends on the SRP has yet toJosef Brunner1, Jan-Willem L.de Gier2, be defined.Gunnar von Heijne2, Chris van der Does3, In eukaryotic cells, a related but more complex SRPArnold J.M.Driessen3, Bauke Oudega and mediates co-translational targeting of both secreted andJoen Luirink4 membrane proteins to the membrane of the endoplasmic