Abstract

The interplay between experiments and theoretical approaches can support the exploration of the function of neuronal circuits in the cortex. In this review we exemplify such a proceeding with a study on the functional role of spike timing and gamma-oscillations, and their relation to associative activity feedback through cortex-intrinsical synaptic connections. We first discern the theoretical approaches in general that have been most important in brain research, in particular, those approaches focusing on the biophysical, the functional, and the computational aspect. It is demonstrated how results from computational model studies on different levels of abstraction can constrain the functionality of associative memory expected in real cortical neuronal circuits. These constraints will be used to implement a computational model of associative memory on the base of biophysically elaborated compartmental neurons developed by Pinsky and Rinzel [43]. We run simulation experiments...

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