Abstract

The Unified Medical Language System (http://umlsks.nlm.nih.gov) is a repository of biomedical vocabularies developed by the US National Library of Medicine. The UMLS integrates over 2 million names for some 900 000 concepts from more than 60 families of biomedical vocabularies, as well as 12 million relations among these concepts. Vocabularies integrated in the UMLS Metathesaurus include the NCBI taxonomy, Gene Ontology, the Medical Subject Headings (MeSH), OMIM and the Digital Anatomist Symbolic Knowledge Base. UMLS concepts are not only inter-related, but may also be linked to external resources such as GenBank. In addition to data, the UMLS includes tools for customizing the Metathesaurus (MetamorphoSys), for generating lexical variants of concept names (lvg) and for extracting UMLS concepts from text (MetaMap). The UMLS knowledge sources are updated quarterly. All vocabularies are available at no fee for research purposes within an institution, but UMLS users are required to sign a license agreement. The UMLS knowledge sources are distributed on CD-ROM and by FTP.

Citations

187	RefSeq and LocusLink: NCBI gene-centered resources - Pruitt, Maglott - 2001
145	Effective mapping of biomedical text to the umls metathesaurus: the metamap program - Aronson
73	TAMBIS: Transparent access to multiple bioinformatics information sources - Stevens, Baker, et al. - 2000
27	The representation of meaning - McCray, Nelson - 1995
15	MGD: the Mouse Genome Database - Blake, Richardson, et al. - 2003
8	D: PubMed: bridging the information gap - McEntyre, Lipman
5	et al. The Gene Ontology Consortium (2000) Gene ontology: tool for the uni®cation of biology - Ashburner, Ball, et al.