Binary Analysis and Optimization-Based Normalization of Gene Expression Data

Binary Analysis and Optimization-Based Normalization of Gene Expression Data (2002)

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by Ilya Shmulevich , Wei Zhang

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@MISC{Shmulevich02binaryanalysis,
    author = {Ilya Shmulevich and Wei Zhang},
    title = {Binary Analysis and Optimization-Based Normalization of Gene Expression Data},
    year = {2002}
}

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Abstract

Motivation: Most approaches to gene expression analysis use real-valued expression data, produced by highthroughput screening technologies, such as microarrays. Often, some measure of similarity must be computed in order to extract meaningful information from the observed data. The choice of this similarity measure frequently has a profound effect on the results of the analysis, yet no standards exist to guide the researcher.

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