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The Science and Ethics of Causal Modeling (2010)

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by Judea Pearl
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BibTeX

@MISC{Pearl10thescience,
    author = {Judea Pearl},
    title = {The Science and Ethics of Causal Modeling},
    year = {2010}
}

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Abstract

The intrinsic schism between causal and associational relations presents profound ethical and methodological problems to researchers in the social and behavioral sciences, ranging from the statement of a problem, to the implementation of a study, to the reporting of finding. This paper describes a causal modeling framework that mitigates these problems and offers a simple, yet formal and principled methodology for empirical research. The framework is based on the Structural Causal Model (SCM) described in [Pearl, 2000b] – a nonparametric extension of structural equation models that provides a mathematical foundation and a friendly calculus for the analysis of causes and counterfactuals. In particular, the paper establishes a methodology for inferring (from a combination of data and assumptions) answers to three types of causal queries: (1) queries about the effects of potential interventions, (also called “causal effects” or “policy evaluation”), (2) queries about probabilities of counterfactuals, (including assessment of “regret,” “attribution,” or “causes of effects”), and (3) queries about direct and indirect effects (also known as “mediation” or “effect decomposition”). Finally, the paper defines the formal and conceptual relationships between the structural and potential-outcome frameworks and demonstrates a symbiotic analysis that uses the strong features of both.

Citations

766 Causality: Models, reasoning, and inference - Pearl - 2001
544 The central role of the propensity score in observational studies for causal effects - Rosenbaum, Rubin - 1983
354 Graphical Models in Applied Multivariate Statistics - Whittaker - 2009
335 DA: The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations - RW, Kenny - 1986
207 Identification of Causal Effects Using Instrumental Variables (with Discussion - Angrist, Imbens, et al. - 1996
147 Conditional independence in statistical theory - Dawid - 1979
131 Causal diagrams for empirical research - Pearl - 1995
112 A new approach to causal inference in mortality studies with a sustained exposure period – applications to control of the healthy workers survivor effect - Robins - 1986
79 Comment: Graphical models, causality, and intervention - Pearl - 1993
78 Causal diagrams for epidemiologic research. Epidemiology - Greenland, Pearl, et al.
78 PR: Observational studies - Rosenbaum
75 Planning of Experiments - Cox - 1958
63 Causal inference without counterfactuals (with comments and rejoinder - Dawid - 2000
53 S: Identifiability and exchangeability for direct and indirect effects. Epidemiology - JM, Greenland - 1992
52 Probabilistic evaluation of sequential plans from causal models with hidden variables - Pearl, Robins - 1995
47 A general identification condition for causal effects - Tian, Pearl - 2002
43 Direct and indirect effects - Pearl - 2005
42 Causal inference, path analysis, and recursive structural equations models - Holland - 1988
41 Probabilistic evaluation of counterfactual queries - Balke, Pearl - 1994
38 Graphs, causality, and structural equation models - Pearl - 1998
38 Mediation in experimental and nonexperimental studies: New procedures and recommendations - Shrout, Bolger - 2002
37 Counterfactuals and policy analysis in structural models - Balke, Pearl - 1995
35 Linear dependencies represented by chain graphs - Cox, Wermuth - 1993
33 Identification of conditional interventional distributions - Shpitser, Pearl - 2006
26 Mediating instrumental variables - Pearl - 1993
25 Direct and indirect causal effects via potential outcomes - Rubin - 2004
24 Causal inference using potential outcomes: Design, modeling, decisions - Rubin - 2005
24 Cause and counterfactual - Simon, Rescher - 1966
24 Counterfactuals and Causal Inference: Methods and Principles for Social Research (Analytical Methods for Social Research - Morgan, Winship - 2007
21 Identifiability of path-specific effects - Avin, Shpitser, et al. - 2005
21 An extended class of instrumental variables for the estimation of causal effects - Chalak, White - 2006
18 Identification, inference, and sensitivity analysis for causal mediation effects - Imai, Keele, et al. - 2008
17 Finding minimal separating sets - Tian, Paz, et al. - 1998
15 background knowledge in etiologic inference - Data - 2001
15 Estimating mediated effects in prevention studies - MacKinnon, Dwyer - 1993
15 networksofplausible inference - Pearl - 1988
14 Four types of effect modification: A classification based on directed acyclic graphs - VanderWeele, Robins - 2007
13 Letter to the editor: Remarks on the method of propensity scores - Pearl - 2009
13 Testing and estimation of directed effects by reparameterizing directed acyclic with structural nested models - Robins - 1999
12 Mediation analysis - MacKinnon, Fairchild, et al. - 2007
12 Probabilities of causation: Bounds and identification - Tian, Pearl - 2000
12 Marginal structural models for the estimation of direct and indirect effects - VanderWeele - 2009
12 2008): “On identifying total effects in the presence of latent variables and selection - Cai, Kuroki
12 2009a): “Causal inference in statistics: An overview - Pearl
11 2009): “Opening the black box: A motivation for the assessment of mediation - Hafeman, Schwartz
11 The intermediate endpoint effect in logistic and probit regression. Clin Trials - MacKinnon, Lockwood, et al.
11 Comment on A.P. Dawid’s, Causal inference without counterfactuals - Pearl
11 Statistics and causal inference: A review - Pearl - 2003
11 The design versus the analysis of observational studies for causal effects: Parallels with the design of randomized trials - Rubin - 2007
10 Confounding equivalence in observational studies - Pearl, Paz - 2009
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