GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data

GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data (2004)

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by C. C. Wu , H. C. Huang , H. F. Juan , S. T. Chen

Venue:	BIOINFORMATICS
Citations:	6 - 0 self

BibTeX

@ARTICLE{Wu04genenetwork:an,
    author = {C. C. Wu and H. C. Huang and H. F. Juan and S. T. Chen},
    title = {GeneNetwork: an interactive tool for reconstruction of genetic networks using microarray data},
    journal = {BIOINFORMATICS},
    year = {2004},
    volume = {20},
    pages = {3691--3693}
}

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Abstract

Recently a variety of high-troughput experimental techniques, such as DNA microarray, are opening system-level perspectives of living organisms on the molecular level. Inferring genetic network architecture from time series data generated from these technologies is an important computational methods to help us to understand the system behavior of living organisms. We developed an interactive software, GeneNetwork, which supports four representative reverse engineering models and three data interpolation approaches. It enables users readily reconstruct genetic network based on microarray data without being intimately involved with mathematical computation. A simple graphical user interface enables rapid, intuitive mapping, and analysis of the reconstructed network. These high-level capabilities of GeneNetwork lead biologists to explore biological systems at the system-level.

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