A Framework for Three-Dimensional Simulation of Morphogenesis (2004)
| Citations: | 14 - 9 self |
BibTeX
@MISC{Cickovski04aframework,
author = {Trevor Cickovski and Chengbang Huang and Rajiv Chaturvedi and Tilmann Glimm and H.G.E. Hentschel and Mark Alber and James A. Glazier and Stuart A. Newman and Jesus A. Izaguirre},
title = {A Framework for Three-Dimensional Simulation of Morphogenesis},
year = {2004}
}
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Abstract
We present COMPUCELL3D, a software framework for three-dimensional simulation of morphogenesis in different organisms. COMPUCELL3D employs biologically relevant models for cell clustering, growth, and interaction with chemical fields. COMPUCELL3D uses design patterns for speed, efficient memory management, extensibility, and flexibility, permitting the simulation of various organisms. We verify COMPUCELL3D by building a model of growth and skeletal pattern formation in the avian (chicken) limb bud. Binaries and source code are available, along with documentation and input files for sample simulations, at http://www.nd.edu/lcls/compucell.
