Alterations in brain and immune function produced by mindfulness meditation

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Alterations in brain and immune function produced by mindfulness meditation (2003)

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by Richard J. Davidson , Jon Kabat-zinn , Jessica Schumacher , Melissa Rosenkranz , Katherine Bonus , John , F. Sheridan

Venue:	Psychosomatic Medicine
Citations:	229 - 5 self

Citations

2917	Development and validation of brief measures of positive and negative affect: The PANAS Scales - Watson, Clark, et al. - 1988 (Show Context) Citation Context ...tracting log-transformed left hemisphere �-power densities from the comparable measure derived from homologous right-sided electrodes. After each of the writing periods, subjects were given the PANAS =-=(23)-=- in state form. In addition, at each assessment, they were administered the PANAS in trait form, along with the Spielberger State-Trait Anxiety Inventory (24) in trait form. In addition, subjects in t...
477	Full catastrophe living: using the wisdom of your body and mind to face stress, pain and illness. Delacourt, - Kabat-Zinn - 1990 (Show Context) Citation Context ...ation group. The meditation training (known as MBSR) was delivered by J.K.-Z., and was directly modeled on the MBSR intervention originally developed at the University of Massachusetts Medical Center =-=(25, 26)-=-. The effects of MBSR have been reported in numerous clinical studies with diverse populations, as well as in medical students (27, 28). One study demonstrated significant effects of mindfulness on th...
332	Mindfulness training as a clinical intervention: a conceptual and empirical review. Clinical Psychology: Science and Practice, - Baer - 2003 (Show Context) Citation Context ...fects of mindfulness on the rate of skin clearing in patients with moderate to severe psoriasis (29) Two recent reviews of MBSR research called for studies to elucidate potential mechanisms of action =-=(30, 31)-=-. The training consisted of a class that met weekly for 2.5 to 3 hours per class, along with a silent seven-hour retreat that was held during week 6 of the course. In addition, subjects were assigned ...
135	Three-year follow-up and clinical implications of a mindfulness meditation-based stress reduction intervention in the treatment of anxiety disorders. - Miller, Fletcher, et al. - 1995
93	The functional neuroanatomy of emotion and affective style. Trends Cogn Sci 3:11–21. - RJ, Irwin - 1999 (Show Context) Citation Context ...tional neuroanatomical substrates of emotion and affective style, we have established that the frontal regions of the brain exhibit a specialization for certain forms of positive and negative emotion =-=(9, 10)-=-. Left-sided activation in several anterior regions is observed during certain forms of positive emotion and in subjects with more dispositional positive affect (10, 11). We therefore hypothesized tha...
83	Health Psychology: Psychological factors and physical disease from the perspective of human psychoneuroimmunology. - Cohen, Herbert - 1996
65	Psychosocial modifiers of immunocompetence in medical students. Psychosom Med - JK, Garner, et al. - 1984
53	Soulsby JM, Lau MA. Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy - JD, ZV, et al.
47	Chronic stress alters the immune response to influenza virus vaccine in older adults. - JK, Glaser, et al. - 1996 (Show Context) Citation Context ...uppressor (CD3�CD) lymphocytes in HIV-infected men (18). On the basis of recent research demonstrating the negative impact of stressful life events on antibody titers in response to influenza vaccine =-=(19)-=-, we vaccinated all subjects at the end of the 8-week meditation program (in mid November), along with the subjects in wait-list control group at the same time. We hypothesized that the meditators wou...
43	Effects of mindfulness-based stress reduction on medical and premedical students. - SL, GE, et al. - 1998 (Show Context) Citation Context ...ally developed at the University of Massachusetts Medical Center (25, 26). The effects of MBSR have been reported in numerous clinical studies with diverse populations, as well as in medical students =-=(27, 28)-=-. One study demonstrated significant effects of mindfulness on the rate of skin clearing in patients with moderate to severe psoriasis (29) Two recent reviews of MBSR research called for studies to el...
24	NH: Emotion, plasticity, context, and regulation: perspectives from affective neuroscience. Psychol Bull - RJ, DC, et al. - 2000 (Show Context) Citation Context ...bars reflect means � SE. Psychosomatic Medicine 65:564–570 (2003) 565R. J. DAVIDSON et al. trends. For the baseline period assessments, there was a marginally significant Group � Time linear trend (F=-=(1,33)-=- � 3.73, p � .06) and a significant main effect for Group (across time periods; F(1,33) � 4.57, p � .04). When the comparison of change from baseline for each time period was examined, there was a sig...
20	The influence of psychological stress on the immune response to vaccines. - Glaser, Kiecolt-Glaser, et al. - 1998
19	What do we really know about mindfulness-based stress reduction? Psychosom Med; - SR - 2002 (Show Context) Citation Context ...fects of mindfulness on the rate of skin clearing in patients with moderate to severe psoriasis (29) Two recent reviews of MBSR research called for studies to elucidate potential mechanisms of action =-=(30, 31)-=-. The training consisted of a class that met weekly for 2.5 to 3 hours per class, along with a silent seven-hour retreat that was held during week 6 of the course. In addition, subjects were assigned ...
19	Affective style, psychopathology, and resilience: brain mechanisms and plasticity. - RJ - 2000 (Show Context) Citation Context ...ons, but not significant [F(1,31) � 3.16, p � .08]. In response to the negative emotion induction for the central leads, an omnibus MANOVA revealed a marginally significant Group � Time interaction [F=-=(2,32)-=- � 2.78, p � .08], along with a marginally significant linear trend for this interaction [F(1,33) � 3.45, p � .07]. In addition, there was a significant main effect for Group [F(1,33) � 6.78, p � .01]...
17	Changed pattern of regional glucose metabolism during yoga meditative relaxation. - Herzog, Lele, et al. - 1990
16	Emotion and affective style: Hemispheric substrates. Psychol Sci. - RJ - 1992 (Show Context) Citation Context ...tional neuroanatomical substrates of emotion and affective style, we have established that the frontal regions of the brain exhibit a specialization for certain forms of positive and negative emotion =-=(9, 10)-=-. Left-sided activation in several anterior regions is observed during certain forms of positive emotion and in subjects with more dispositional positive affect (10, 11). We therefore hypothesized tha...
12	Lenderking WR, Santorelli SF: Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. - Kabat-Zinn, AO, et al. - 1992
11	Psychometric properties of resting anterior EEG asymmetry: temporal stability and internal consistency. Psychophys - AJ, RJ, et al. - 1992 (Show Context) Citation Context ...ss the scalp and referenced to linked ears during 8 1-minute baseline trials, four with eyes open and four with eyes closed, presented in counterbalanced order according to our established procedures =-=(22)-=-. EEG was also recorded during a 1-minute period before and a 3-minute period after subjects wrote about one of three of the most positive and negative experiences in their life. These events were lis...
10	A 15O-H2O PET study of meditation and the resting state of normal consciousness. - HC, TW, et al. - 1999 (Show Context) Citation Context ...ed. RESULTS Affect and Anxiety Measures We evaluated self-report measures of positive and negative affect and anxiety before and after the training. There was a significant Group � Time interaction [F=-=(1,31)-=- � 5.45, p � .05] on a measure of trait anxiety, the Spielberger State-Trait Anxiety Inventory (24), accounted for by a reduction in anxiety for subjects in the meditation group from Time 1 to Time 2 ...
9	Influence of a mindfulness-based stress reduction intervention on rates of skin clearing in patients with moderate to severe psoriasis undergoing phototherapy (UVB) and photochemotherapy (PUVA). Psychosom Med. - Kabat-Zinn, Wheeler, et al. - 1998 (Show Context) Citation Context ...with diverse populations, as well as in medical students (27, 28). One study demonstrated significant effects of mindfulness on the rate of skin clearing in patients with moderate to severe psoriasis =-=(29)-=- Two recent reviews of MBSR research called for studies to elucidate potential mechanisms of action (30, 31). The training consisted of a class that met weekly for 2.5 to 3 hours per class, along with...
7	Effects on regional cerebral blood flow of transcendental meditation. - Jevning, Anand, et al. - 1996 (Show Context) Citation Context ...wait-list control group (p � .05 for each; see Figure 2). The omnibus MANOVA performed on the positive emotion induction condition revealed a marginally significant overall Group � Time interaction [F=-=(2,26)-=- � 2.52, p � .10] for the anterior temporal (T3/4) electrode leads. When the comparison of change from baseline for each time period was examined, there was a significant Group � Time interaction [F(1...
6	Guidelines for quantitative electroencephalography in research contexts - Pivik, Broughton, et al. - 1993 (Show Context) Citation Context ...EG for eye movements) was recorded during both baseline conditions and in response to a positive and negative emotion induction using methods that have been extensively described in previous research =-=(20, 21)-=-. EEG was recorded from 27 sites distributed across the scalp and referenced to linked ears during 8 1-minute baseline trials, four with eyes open and four with eyes closed, presented in counterbalanc...
4	Meditation: A modulator of the immune response to physical stress? A brief report. - Solberg, Halvorsen, et al. - 1995 (Show Context) Citation Context ...ciated with enhanced immune function using measures of NK activity (12, 13). There has been a paucity of serious research attention to possible immune alterations that might be produced by meditation =-=(14)-=-. This is somewhat surprising in light of the fact that negative psychosocial influences on immunity have now been well established (15–17). Recent research indicates that relaxation and stress manage...
3	Coe CC, Dolski I, Donzella B. Individual differences in prefrontal activation asymmetry predict natural killer cell activity at rest and in response to challenge. Brain Behav Immun - RJ - 1999 (Show Context) Citation Context ...in a wait-list control group. Recent studies have established that greater relative leftsided anterior activation at baseline is associated with enhanced immune function using measures of NK activity =-=(12, 13)-=-. There has been a paucity of serious research attention to possible immune alterations that might be produced by meditation (14). This is somewhat surprising in light of the fact that negative psycho...
3	RL, Lushene RE, Vagg PR, Jacobs GA. Manual for the state-trait anxiety inventory. Palo Alto CA: Consulting Psychologists - CD, Gorsuch - 1983 (Show Context) Citation Context ...ng periods, subjects were given the PANAS (23) in state form. In addition, at each assessment, they were administered the PANAS in trait form, along with the Spielberger State-Trait Anxiety Inventory =-=(24)-=- in trait form. In addition, subjects in the meditation group were asked to provide daily reports of the frequency and number of minutes and techniques of formal meditation practice. Blood draws were ...
3	thy self: lessons on mindfulness in medicine - Heal - 1999 (Show Context) Citation Context ...ation group. The meditation training (known as MBSR) was delivered by J.K.-Z., and was directly modeled on the MBSR intervention originally developed at the University of Massachusetts Medical Center =-=(25, 26)-=-. The effects of MBSR have been reported in numerous clinical studies with diverse populations, as well as in medical students (27, 28). One study demonstrated significant effects of mindfulness on th...
2	Saron C, Senulis J, Friesen WV. Approach/ withdrawal and cerebral asymmetry: Emotional expression and brain physiology - RJ, Ekman - 1990 (Show Context) Citation Context ...f positive and negative emotion (9, 10). Left-sided activation in several anterior regions is observed during certain forms of positive emotion and in subjects with more dispositional positive affect =-=(10, 11)-=-. We therefore hypothesized that because meditation decreases anxiety and increases positive affect, subjects who were practicing meditation should show increased left-sided activation in these territ...
1	How does cognitive therapy prevent Psychosomatic Medicine 65:564–570 - JD, Segal, et al. - 2003
1	Levinson DM. Effects of meditation on stress, health, and affect. Medical-Psychother: Int J - DL - 1992
1	RJ, Coe CL, Wheeler RW, Tomarken AJ, Ershler WB. Frontal brain asymmetry and immune function. Behav Neurosci - DH, Davidson - 1991 (Show Context) Citation Context ...in a wait-list control group. Recent studies have established that greater relative leftsided anterior activation at baseline is associated with enhanced immune function using measures of NK activity =-=(12, 13)-=-. There has been a paucity of serious research attention to possible immune alterations that might be produced by meditation (14). This is somewhat surprising in light of the fact that negative psycho...
1	Cognitive-based stress management intervention effects on anxiety, 24-hr urinary norepinephrine output, and T-cytotoxic/suppressor cells over time among symptomatic HIV infected gay men. J Consult Clin Psychol 2000;68:31–45 - MH (Show Context) Citation Context ...on immunity have now been well established (15–17). Recent research indicates that relaxation and stress management procedures increase T-cytotoxic/suppressor (CD3�CD) lymphocytes in HIV-infected men =-=(18)-=-. On the basis of recent research demonstrating the negative impact of stressful life events on antibody titers in response to influenza vaccine (19), we vaccinated all subjects at the end of the 8-we...
1	Mindfulness-based stress reduction: Past, present, and future - Kabat-Zinn - 2003 (Show Context) Citation Context ...ally developed at the University of Massachusetts Medical Center (25, 26). The effects of MBSR have been reported in numerous clinical studies with diverse populations, as well as in medical students =-=(27, 28)-=-. One study demonstrated significant effects of mindfulness on the rate of skin clearing in patients with moderate to severe psoriasis (29) Two recent reviews of MBSR research called for studies to el...
1	The functional neuroanatomy of the appetitive and aversive motivation systems: Results from an FDG-PET study. Neuroimage - SK, CL, et al. - 1996 (Show Context) Citation Context ...we have found robust asymmetric increases in left premotor activation in response to positive emotional pictures in a study that measured regional glucose metabolism with positron emission tomography =-=(34)-=-. The fact that there was no significant increase in dispositional positive affect in the meditation group may be related to the failure to detect increases in left prefrontal activation. It may well ...
1	does cognitive therapy prevent TABLE 1. Self-Reported Daily Practice in the Meditation Group Time 2 Time 3 Means SD Range Means SD Range How regularly do you practice (0–6 scale) 2.48 2.14 0–6 1.70 1.66 0–6 How long do you practice (0–30 minutes/session - How - 2003