Abstract not found

We present an automatic sub-pixel registration algorithm that minimizes the mean square intensity difference between a reference and a test data set, which can be either images (2-D) or volumes (3-D). It uses an explicit spline representation of the images in conjunction with spline processing, and is based on a coarse-to-fine iterative strategy (pyramid approach). The minimization is performed according to a new variation (ML*) of the Marquardt-Levenberg algorithm for non-linear least-square optimization. The geometric deformation model is a global 3-D affine transformation that can be optionally restricted to rigid-body motion (rotation and translation), combined with isometric scaling. It also includes an optional adjustment of image contrast differences. We obtain excellent results for the registration of intra-modality Positron Emission Tomography (PET) and functional Magnetic Resonance Imaging (fMRI) data. We conclude that the multi-resolution refinement strategy is more robust than a comparable single-stage method, being less likely to be trapped into a false local optimum. In addition, our improved version of the Marquardt-Levenberg algorithm is faster.

Abstract — Image interpolation techniques often are required in medical imaging for image generation (e.g., discrete back projection for inverse Radon transform) and processing such as compression or resampling. Since the ideal interpolation function spatially is unlimited, several interpolation kernels of finite size have been introduced. This paper compares 1) truncated and windowed sinc; 2) nearest neighbor; 3) linear; 4) quadratic; 5) cubic B-spline; 6) cubic; g) Lagrange; and 7) Gaussian interpolation and approximation techniques with kernel sizes from 1 2 1upto 8 2 8. The comparison is done by: 1) spatial and Fourier analyses; 2) computational complexity as well as runtime evaluations; and 3) qualitative and quantitative interpolation error determinations for particular interpolation tasks which were taken from common situations in medical image processing. For local and Fourier analyses, a standardized notation is introduced

A probabilistic framework is presented that enables image registration, tissue classification, and bias correction to be combined within the same generative model. A derivation of a log-likelihood objective function for the unified model is provided. The model is based on a mixture of Gaussians and is extended to incorporate a smooth intensity variation and nonlinear registration with tissue probability maps. A strategy for optimising the model parameters is described, along with the requisite partial derivatives of the objective function.

In a previous paper, we proposed a general Fourier method that provides an accurate prediction of the approximation error, irrespective of the scaling properties of the approximating functions. Here, we apply our results when these functions satisfy the usual two-scale relation encountered in dyadic multiresolution analysis. As a consequence of this additional constraint, the quantities introduced in our previous paper can be computed explicitly as a function of the refinement filter. This is, in particular, true for the asymptotic expansion of the approximation error for biorthonormal wavelets as the scale tends to zero. One of the contributions of this paper is the computation of sharp, asymptotically optimal upper bounds for the least-squares approximation error. Another contribution is the application of these results to B-splines and Daubechies scaling functions, which yields explicit asymptotic developments and upper bounds. Thanks to these explicit expressions, we can quantify ...

Abstract—This chapter presents a survey of interpolation and resampling techniques in the context of exact, separable interpolation of regularly sampled data. In this context, the traditional view of interpolation is to represent an arbitrary continuous function as a discrete sum of weighted and shifted synthesis functions—in other words, a mixed convolution equation. An important issue is the choice of adequate synthesis functions that satisfy interpolation properties. Examples of finite-support ones are the square pulse (nearest-neighbor interpolation), the hat function (linear interpolation), the cubic Keys' function, and various truncated or windowed versions of the sinc function. On the other hand, splines provide examples of infinite-support interpolation functions that can be realized exactly at a finite, surprisingly small computational cost. We discuss implementation issues and illustrate the performance of each synthesis function. We also highlight several artifacts that may arise when performing interpolation, such as ringing, aliasing, blocking and blurring. We explain why the approximation order inherent in the synthesis function is important to limit these interpolation artifacts, which motivates the use of splines as a tunable way to keep them in check without any significant cost penalty. I.

This paper presents a chronological overview of the developments in interpolation theory, from the earliest times to the present date. It brings out the connections between the results obtained in different ages, thereby putting the techniques currently used in signal and image processing into historical perspective. A summary of the insights and recommendations that follow from relatively recent theoretical as well as experimental studies concludes the presentation. Keywords—Approximation, convolution-based interpolation, history, image processing, polynomial interpolation, signal processing, splines. “It is an extremely useful thing to have knowledge of the true origins of memorable discoveries, especially those that have been found not by accident but by dint of meditation. It is not so much that thereby history may attribute to each man his own discoveries and others should be encouraged to earn like commendation, as that the art of making discoveries should be extended by considering noteworthy examples of it. ” 1 I.

Abstract—Interpolation is required in a variety of medical image processing applications. Although many interpolation techniques are known from the literature, evaluations of these techniques for the specific task of applying geometrical transformations to medical images are still lacking. In this paper we present such an evaluation. We consider convolution-based interpolation methods and rigid transformations (rotations and translations). A large number of sincapproximating kernels are evaluated, including piecewise polynomial kernels and a large number of windowed sinc kernels, with spatial supports ranging from two to ten grid intervals. In the evaluation we use images from a wide variety of medical image modalities. The results show that spline interpolation is to be preferred over all other methods, both for its accuracy and its relatively low computational cost. Keywords—Convolution-based interpolation, spline interpolation, piecewise polynomial kernels, windowed sinc kernels, geometrical transformation, medical images, quantitative evaluation. 1

Abstract. Two digital filters H(z) and F(z) are said to be biorthogonal partners of each other if their cascade H(z)F(z) satisfies the Nyquist or zero-crossing property. Biorthogonal partners arise in many different contexts such as filter bank theory, exact and least squares digital interpolation, and multiresolution theory. They also play a central role in the theory of equalization, especially, fractionally spaced equalizers in digital communications. In this paper we first develop several theoretical properties of biorthogonal partners. We also develop conditions for the existence of biorthogonal partners and FIR biorthogonal pairs, and establish the connections to the Riesz basis property. We then explain how these results play a role in many of the above mentioned applications. 1 1.

Efficient segmentation of globally optimal surfaces representing object boundaries in volumetric data sets is important and challenging in many medical image analysis applications. We have developed an optimal surface detection method capable of simultaneously detecting multiple interacting surfaces, in which the optimality is controlled by the cost functions designed for individual surfaces and by several geometric constraints defining the surface smoothness and interrelations. The method solves the surface segmentation problem by transforming it into computing a minimum s-t cut in a derived arc-weighted directed graph. The proposed algorithm has a low-order polynomial time complexity and is computationally efficient. It has been extensively validated on more than 300 computer-synthetic volumetric images, 72 CT-scanned data sets of different-sized plexiglas tubes, and tens of medical images spanning various imaging modalities. In all cases, the approach yielded highly accurate results. Our approach can be readily extended to higher-dimensional image segmentation.