this paper, we first address fundamental issues in building useful performance-tuning tools and then describe our experience with the AIMS toolkit for tuning parallel and distributed programs on a variety of platforms. AIMS supports source-code instrumentation, run-time monitoring, graphical execution profiles, performance indices and automated modeling techniques as ways to expose performance problems of programs. Using several examples representing a broad range of scientific applications, we illustrate AIMS' effectiveness in exposing performance problems in parallel and distributed programs