Results 1  10
of
16
Dynamic Bayesian Networks: Representation, Inference and Learning
, 2002
"... Modelling sequential data is important in many areas of science and engineering. Hidden Markov models (HMMs) and Kalman filter models (KFMs) are popular for this because they are simple and flexible. For example, HMMs have been used for speech recognition and biosequence analysis, and KFMs have bee ..."
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Cited by 564 (3 self)
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Modelling sequential data is important in many areas of science and engineering. Hidden Markov models (HMMs) and Kalman filter models (KFMs) are popular for this because they are simple and flexible. For example, HMMs have been used for speech recognition and biosequence analysis, and KFMs have been used for problems ranging from tracking planes and missiles to predicting the economy. However, HMMs
and KFMs are limited in their “expressive power”. Dynamic Bayesian Networks (DBNs) generalize HMMs by allowing the state space to be represented in factored form, instead of as a single discrete random variable. DBNs generalize KFMs by allowing arbitrary probability distributions, not just (unimodal) linearGaussian. In this thesis, I will discuss how to represent many different kinds of models as DBNs, how to perform exact and approximate inference in DBNs, and how to learn DBN models from sequential data.
In particular, the main novel technical contributions of this thesis are as follows: a way of representing
Hierarchical HMMs as DBNs, which enables inference to be done in O(T) time instead of O(T 3), where T is the length of the sequence; an exact smoothing algorithm that takes O(log T) space instead of O(T); a simple way of using the junction tree algorithm for online inference in DBNs; new complexity bounds on exact online inference in DBNs; a new deterministic approximate inference algorithm called factored frontier; an analysis of the relationship between the BK algorithm and loopy belief propagation; a way of
applying RaoBlackwellised particle filtering to DBNs in general, and the SLAM (simultaneous localization
and mapping) problem in particular; a way of extending the structural EM algorithm to DBNs; and a variety of different applications of DBNs. However, perhaps the main value of the thesis is its catholic presentation of the field of sequential data modelling.
Learning the structure of dynamic probabilistic networks
, 1998
"... Dynamic probabilistic networks are a compact representation of complex stochastic processes. In this paper we examine how to learn the structure of a DPN from data. We extend structure scoring rules for standard probabilistic networks to the dynamic case, and show how to search for structure when so ..."
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Cited by 217 (13 self)
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Dynamic probabilistic networks are a compact representation of complex stochastic processes. In this paper we examine how to learn the structure of a DPN from data. We extend structure scoring rules for standard probabilistic networks to the dynamic case, and show how to search for structure when some of the variables are hidden. Finally, we examine two applications where such a technology might be useful: predicting and classifying dynamic behaviors, and learning causal orderings in biological processes. We provide empirical results that demonstrate the applicability of our methods in both domains. 1
The Bayes Net Toolbox for MATLAB
 Computing Science and Statistics
, 2001
"... The Bayes Net Toolbox (BNT) is an opensource Matlab package for directed graphical models. BNT supports many kinds of nodes (probability distributions), exact and approximate inference, parameter and structure learning, and static and dynamic models. BNT is widely used in teaching and research: the ..."
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Cited by 176 (2 self)
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The Bayes Net Toolbox (BNT) is an opensource Matlab package for directed graphical models. BNT supports many kinds of nodes (probability distributions), exact and approximate inference, parameter and structure learning, and static and dynamic models. BNT is widely used in teaching and research: the web page has received over 28,000 hits since May 2000. In this paper, we discuss a broad spectrum of issues related to graphical models (directed and undirected), and describe, at a highlevel, how BNT was designed to cope with them all. We also compare BNT to other software packages for graphical models, and to the nascent OpenBayes effort.
Modelling gene expression data using dynamic bayesian networks
, 1999
"... Recently, there has been much interest in reverse engineering genetic networks from time series data. In this paper, we show that most of the proposed discrete time models — including the boolean network model [Kau93, SS96], the linear model of D’haeseleer et al. [DWFS99], and the nonlinear model of ..."
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Cited by 157 (1 self)
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Recently, there has been much interest in reverse engineering genetic networks from time series data. In this paper, we show that most of the proposed discrete time models — including the boolean network model [Kau93, SS96], the linear model of D’haeseleer et al. [DWFS99], and the nonlinear model of Weaver et al. [WWS99] — are all special cases of a general class of models called Dynamic Bayesian Networks (DBNs). The advantages of DBNs include the ability to model stochasticity, to incorporate prior knowledge, and to handle hidden variables and missing data in a principled way. This paper provides a review of techniques for learning DBNs. Keywords: Genetic networks, boolean networks, Bayesian networks, neural networks, reverse engineering, machine learning. 1
Stratified exponential families: Graphical models and model selection
 Annals of Statistics
, 2001
"... JSTOR is a notforprofit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JS ..."
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Cited by 54 (6 self)
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JSTOR is a notforprofit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org.
Inference and Learning in Hybrid Bayesian Networks
, 1998
"... We survey the literature on methods for inference and learning in Bayesian Networks composed of discrete and continuous nodes, in which the continuous nodes have a multivariate Gaussian distribution, whose mean and variance depends on the values of the discrete nodes. We also briefly consider hybrid ..."
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Cited by 25 (2 self)
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We survey the literature on methods for inference and learning in Bayesian Networks composed of discrete and continuous nodes, in which the continuous nodes have a multivariate Gaussian distribution, whose mean and variance depends on the values of the discrete nodes. We also briefly consider hybrid Dynamic Bayesian Networks, an extension of switching Kalman filters. This report is meant to summarize what is known at a sufficient level of detail to enable someone to implement the algorithms, but without dwelling on formalities.
Models and Selection Criteria for Regression and Classification
 Uncertainty in Arificial Intelligence 13
, 1997
"... When performing regression or classification, we are interested in the conditional probability distribution for an outcome or class variable Y given a set of explanatory or input variables X. We consider Bayesian models for this task. In particular, we examine a special class of models, which we ca ..."
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Cited by 23 (2 self)
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When performing regression or classification, we are interested in the conditional probability distribution for an outcome or class variable Y given a set of explanatory or input variables X. We consider Bayesian models for this task. In particular, we examine a special class of models, which we call Bayesian regression/classification (BRC) models, that can be factored into independent conditional (yjx) and input (x) models. These models are convenient, because the conditional model (the portion of the full model that we care about) can be analyzed by itself. We examine the practice of transforming arbitrary Bayesian models to BRC models, and argue that this practice is often inappropriate because it ignores prior knowledge that may be important for learning. In addition, we examine Bayesian methods for learning models from data. We discuss two criteria for Bayesian model selection that are appropriate for repression/classification: one described by Spiegelhalter et al. (1993), and an...
Learning Bayes net structure from sparse data sets
, 2001
"... There are essentially two kinds of approaches for learning the structure of Bayesian Networks (BNs) from data. The first approach tries to find a graph which satis es all the constraints implied by the empirical conditional independencies measured in the data [PV91, SGS00a, Shi00]. The second approa ..."
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Cited by 12 (2 self)
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There are essentially two kinds of approaches for learning the structure of Bayesian Networks (BNs) from data. The first approach tries to find a graph which satis es all the constraints implied by the empirical conditional independencies measured in the data [PV91, SGS00a, Shi00]. The second approach searches through the space of models (either DAGs or PDAGs), and uses some scoring metric (typically Bayesian or some approximation, such as BIC/MDL) to evaluate the models [CH92, Hec95, Hec98, Kra98], typically returning the highest scoring model found. Our main interest is in learning BN structure from gene expression data [FLNP00, HGJY01, MM99, SGS00b]. In domains such as this, where the ratio of the number of observations to the number of variables is low (i.e., when we have sparse data), selecting a threshold for the conditional independence (CI) tests can be tricky, and repeated use of such tests can lead to inconsistencies [DD99]. Bayesian s...
Embedded Bayesian Network Classifiers
, 1997
"... Lowdimensional probability models for local distribution functions in a Bayesian network include decision trees, decision graphs, and causal independence models. We describe a new probability model for discrete Bayesian networks, which we call an embedded Bayesian network classifier or EBNC. The mo ..."
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Cited by 9 (2 self)
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Lowdimensional probability models for local distribution functions in a Bayesian network include decision trees, decision graphs, and causal independence models. We describe a new probability model for discrete Bayesian networks, which we call an embedded Bayesian network classifier or EBNC. The model for a node Y given parents X is obtained from a (usually different) Bayesian network for Y and X in which X need not be the parents of Y . We show that an EBNC is a special case of a softmax polynomial regression model. Also, we show how to identify a nonredundant set of parameters for an EBNC, and describe an asymptotic approximation for learning the structure of Bayesian networks that contain EBNCs. Unlike the decision tree, decision graph, and causal independence models, we are unaware of a semantic justification for the use of these models. Experiments are needed to determine whether the models presented in this paper are useful in practice. Keywords: Bayesian networks, model dimen...
Eils R: Inferring Genetic Regulatory Logic from Expression Data
 Bioinformatics
"... Motivation: High throughput molecular genetics methods allow to collect data about expression of genes at different time points and under different conditions. The challenge is to infer gene regulatory interactions from this data and to get insight into the mechanisms of genetic regulation. Results: ..."
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Cited by 8 (0 self)
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Motivation: High throughput molecular genetics methods allow to collect data about expression of genes at different time points and under different conditions. The challenge is to infer gene regulatory interactions from this data and to get insight into the mechanisms of genetic regulation. Results: We propose a model for genetic regulatory interactions, which has a biologically motivated Boolean logic semantics, but is of probabilistic nature, hence being able to confront noisy biological process and data. We propose a method for learning the model from data based on Bayesian approach and utilizing Gibbs sampling. We tested our method with previously published data of the S.cerevisiae cell cycle and found relations between genes consistent with biological knowledge.