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...s et al., 2013). Segmentation is useful for various tasks: to accurately localize prostate boundaries for radiotherapy (Pasquier et al., 2007), perform volume estimation to track disease progression (=-=Toth et al., 2011a-=-), to initialize multimodal registration algorithms (Hu et al., 2012) or to obtain the region of interest for computer-aided detection of prostate cancer (Vos et al., 2012; Tiwari et al., 2013), among...