Abstract. We are part of a multi-disciplinary team investigating new understandings of stem cell behaviour, and specifically looking novel ideas about how adult stem cells behave and organise themselves in the human body. We have used different methods and mechanisms for investigating and interpreting these new ideas from medical science. These have included mathematical modelling, simulation and visualisation as well as a series of art pieces that have resulted from looking at the overall nature of our combined multi-disciplinary attempt to investigate new theories of biological organisation. In this paper we look at several issues relating to our project. First, we provide reasons for why formal models and simulations are needed to explore this growing area of research. Is there an argument to suggest that we need simulations as a way in to understanding various properties of stem cells that are observed in wet lab experiments? Next, an introduction on current theoretical models of stem cells is presented along with an outline of some of the problems and limitations of these approaches. We then provide an overview of our agent-based model of stem cells, and discuss strategies for implementing

A framework for the mind-matter problem in a holistic universe which has no parts is outlined. The conceptual structure of modern quantum theory suggests to use complementary Boolean descriptions as elements for a more comprehensive non-Boolean description of a world without an apriorigiven mind-matter distinction. Such a description in terms of a locally Boolean but globally non-Boolean structure makes allowance for the fact that Boolean descriptions play a privileged role in science. If we accept the insight that there are no ultimate building blocks, the existence of holistic correlations between contextually chosen parts is a natural consequence. The main problem of a genuinely non-Boolean description is to find an appropriate partition of the universe of discourse. If we adopt the idea that all fundamental laws of physics are invariant under time translations, then we can consider a partition of the world into a tenseless and a tensed domain. In the sense of a regulative principle, the material domain is defined as the tenseless domain with its homogeneous time. The tensed domain contains the mental domain with a tensed time characterized by a privileged position, the Now. Since this partition refers to two complementary descriptions which are not given apriori,wehavetoexpectcorrelations between these two domains. In physics it corresponds to Newton’s separation of universal laws of nature and contingent initial conditions. Both descriptions have a non-Boolean structure and can be encompassed into a single non-Boolean description. Tensed and tenseless time can be synchronized by holistic correlations. 1.

The status of the uncertainty relations varies between the different interpretations of quantum mechanics. At one end of the scale, for Heisenberg they showed the fundamental limits of applicability of the wave and particle pictures separately. At the other end, in hidden variable theories they are merely statistical mechanical relations of no foundational