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83
Direct and Indirect Effects
, 2005
"... The direct effect of one event on another can be defined and measured by holding constant all intermediate variables between the two. Indirect effects present conceptual and practical difficulties (in nonlinear models), because they cannot be isolated by holding certain variables constant. This pape ..."
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Cited by 76 (22 self)
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The direct effect of one event on another can be defined and measured by holding constant all intermediate variables between the two. Indirect effects present conceptual and practical difficulties (in nonlinear models), because they cannot be isolated by holding certain variables constant. This paper presents a new way of defining the effect transmitted through a restricted set of paths, without controlling variables on the remaining paths. This permits the assessment of a more natural type of direct and indirect effects, one that is applicable in both linear and nonlinear models and that has broader policyrelated interpretations. The paper establishes conditions under which such assessments can be estimated consistently from experimental and nonexperimental data, and thus extends pathanalytic techniques to nonlinear and nonparametric models.
Graphs, Causality, And Structural Equation Models
, 1998
"... Structural equation modeling (SEM) has dominated causal analysis in the social and behavioral sciences since the 1960s. Currently, many SEM practitioners are having difficulty articulating the causal content of SEM and are seeking foundational answers. ..."
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Cited by 44 (14 self)
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Structural equation modeling (SEM) has dominated causal analysis in the social and behavioral sciences since the 1960s. Currently, many SEM practitioners are having difficulty articulating the causal content of SEM and are seeking foundational answers.
Identification, inference, and sensitivity analysis for causal mediation effects
, 2008
"... Abstract. Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in the causal paths between the treatment and outcome ..."
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Cited by 30 (3 self)
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Abstract. Causal mediation analysis is routinely conducted by applied researchers in a variety of disciplines. The goal of such an analysis is to investigate alternative causal mechanisms by examining the roles of intermediate variables that lie in the causal paths between the treatment and outcome variables. In this paper we first prove that under a particular version of sequential ignorability assumption, the average causal mediation effect (ACME) is nonparametrically identified. We compare our identification assumption with those proposed in the literature. Some practical implications of our identification result are also discussed. In particular, the popular estimator based on the linear structural equation model (LSEM) can be interpreted as an ACME estimator once additional parametric assumptions are made. We show that these assumptions can easily be relaxed within and outside of the LSEM framework and propose simple nonparametric estimation strategies. Second, and perhaps most importantly, we propose a new sensitivity analysis that can be easily implemented by applied researchers within the LSEM framework. Like the existing identifying assumptions, the proposed sequential ignorability assumption may be too strong in many applied settings. Thus, sensitivity analysis is essential in order to examine the robustness of empirical findings to the possible existence of an unmeasured confounder. Finally, we apply the proposed methods to a randomized experiment from political psychology. We also make easytouse software available to implement the proposed methods. Key words and phrases: Causal inference, causal mediation analysis, direct and indirect effects, linear structural equation models, sequential ignorability, unmeasured confounders. 1.
Identifiability of pathspecific effects
 In Proceedings of the Nineteenth International Joint Conference on Artificial Intelligence IJCAI05
, 2005
"... Counterfactual quantities representing pathspecific effects arise in cases where we are interested in computing the effect of one variable on another only along certain causal paths in the graph (in other words by excluding a set of edges from consideration). A recent paper [7] details a method by ..."
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Cited by 27 (14 self)
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Counterfactual quantities representing pathspecific effects arise in cases where we are interested in computing the effect of one variable on another only along certain causal paths in the graph (in other words by excluding a set of edges from consideration). A recent paper [7] details a method by which such an exclusion can be specified formally by fixing the value of the parent node of each excluded edge. In this paper we derive simple, graphical conditions for experimental identifiability of pathspecific effects, namely, conditions under which pathspecific effects can be estimated consistently from data obtained from controlled experiments. 1
Equivalence of the mediation, confounding, and suppression effect
 Prevention Science
, 2000
"... This paper describes the statistical similarities among mediation, confounding, and suppression. Each is quantified by measuring the change in the relationship between an independent and a dependent variable after adding a third variable to the analysis. Mediation and confounding are identical stati ..."
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Cited by 24 (1 self)
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This paper describes the statistical similarities among mediation, confounding, and suppression. Each is quantified by measuring the change in the relationship between an independent and a dependent variable after adding a third variable to the analysis. Mediation and confounding are identical statistically and can be distinguished only on conceptual grounds. Methods to determine the confidence intervals for confounding and suppression effects are proposed based on methods developed for mediated effects. Although the statistical estimation of effects and standard errors is the same, there are important conceptual differences among the three types of effects. KEY WORDS: mediation; confounding; suppression; confidence intervals. Once a relationship between two variables has been established, it is common for researchers to consider the role of a third variable in this relationship (Lazarsfeld, 1955). This paper will examine three types of third variable effects—mediation, confounding, and suppression—in which an additional variable may clarify the nature of the relationship between an independent and a dependent variable. These three concepts have largely been developed within different areas of inquiry, and although the three types of effects are conceptually distinct, they share considerable statistical similarities. Some aspects of the similarity of these concepts have been mentioned in several different articles (Olkin & Finn, 1995; Robins, 1989; Spirtes, Glymour, & Scheines, 1993; Tzelgov & Henik, 1991). In this paper, we demonstrate that mediation, confounding, and suppression effects can each be considered in terms of a general third variable model, and that point and interval estimates of mediation effects can be adapted for use in confounding and suppression frameworks. The paper focuses
Causal inference in statistics: An Overview
, 2009
"... This review presents empirical researcherswith recent advances in causal inference, and stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assumptions that underly all ca ..."
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Cited by 23 (8 self)
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This review presents empirical researcherswith recent advances in causal inference, and stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assumptions that underly all causal inferences, the languages used in formulating those assumptions, the conditional nature of all causal and counterfactual claims, and the methods that have been developed for the assessment of such claims. These advances are illustrated using a general theory of causation based on the Structural Causal Model (SCM) described in Pearl (2000a), which subsumes and unifies other approaches to causation, and provides a coherent mathematical foundation for the analysis of causes and counterfactuals. In particular, the paper surveys the development of mathematical tools for inferring (from a combination of data and assumptions) answers to three types of causal queries: (1) queries about the effects of potential interventions, (also called “causal effects ” or “policy evaluation”) (2) queries about probabilities of counterfactuals, (including assessment of “regret, ” “attribution” or “causes of effects”) and (3) queries about direct and indirect effects (also known as “mediation”). Finally, the paper defines the formal and conceptual relationships between the structural and potentialoutcome frameworks and presents tools for a symbiotic analysis that uses the strong features of both.
The Mediation Formula: A guide to the assessment of causal pathways in nonlinear models
 STATISTICAL CAUSALITY. FORTHCOMING.
, 2011
"... ..."
Statistics and Causal Inference: A Review
, 2003
"... This paper aims at assisting empirical researchers benefit from recent advances in causal inference. The paper stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assump ..."
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Cited by 12 (6 self)
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This paper aims at assisting empirical researchers benefit from recent advances in causal inference. The paper stresses the paradigmatic shifts that must be undertaken in moving from traditional statistical analysis to causal analysis of multivariate data. Special emphasis is placed on the assumptions that underly all causal inferences, the languages used in formulating those assumptions, and the conditional nature of causal claims inferred from nonexperimental studies. These emphases are illustrated through a brief survey of recent results, including the control of confounding, the assessment of causal effects, the interpretation of counterfactuals, and a symbiosis between counterfactual and graphical methods of analysis.
Alternative graphical causal models and the identification of direct effects
, 2009
"... We consider four classes of graphical causal models: the Finest Fully Randomized Causally ..."
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Cited by 11 (2 self)
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We consider four classes of graphical causal models: the Finest Fully Randomized Causally